Isoxazoline-substituted benzamide compound and pesticide

• US 7,662,972 B2
• Filed: 09/05/2006
• Issued: 02/16/2010
• Est. Priority Date: 03/05/2004
• Status: Active Grant

• Current Assignee: Nissan Chemical Corporation
• Original Assignee: Nissan Chemical Industries Limited (Nissan Chemical Corporation)
• Inventors: Yaosaka, Manabu, Mizukoshi, Takashi, Mita, Takeshi, Komoda, Mitsuaki, Kikuchi, Takamasa
• Primary Examiner(s): Anderson; Rebecca L
• Assistant Examiner(s): JACKSON, SHAWQUIA
• Application Number:
  US11/514,921
• Publication Number:
  US 20070066617A1
• Time in Patent Office: 1,260 Days
• Field of Search: 548/240
• US Class Current: 548/240
• CPC Class Codes: A01N 43/80 five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
• CPC Class Codes: A61K 31/421 1,3-Oxazoles, e.g. pemoline, trimethadione
• CPC Class Codes: A61K 9/0053 Mouth and digestive tract, i.e. intraoral and peroral administration rectal administration A61K9/0031
• CPC Class Codes: A61P 33/04 Amoebicides
• CPC Class Codes: A61P 33/06 Antimalarials
• CPC Class Codes: A61P 33/10 Anthelmintics
• CPC Class Codes: A61P 33/12 Schistosomicides
• CPC Class Codes: A61P 33/14 Ectoparasiticides, e.g. scabicides
• CPC Class Codes: C07C 205/11 having nitro groups bound to carbon atoms of six-membered aromatic rings
• CPC Class Codes: C07C 205/12 the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
• CPC Class Codes: C07C 211/52 the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
• CPC Class Codes: C07C 25/02 Monocyclic aromatic halogenated hydrocarbons
• CPC Class Codes: C07C 25/06 Monochloro-benzene
• CPC Class Codes: C07C 25/08 Dichloro-benzenes
• CPC Class Codes: C07C 25/13 containing fluorine
• CPC Class Codes: C07C 25/24 Halogenated aromatic hydrocarbons with unsaturated side chains
• CPC Class Codes: C07C 251/48 with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
• CPC Class Codes: C07C 255/29 containing cyano groups and acylated amino groups bound to the carbon skeleton
• CPC Class Codes: C07C 255/50 to carbon atoms of non-condensed six-membered aromatic rings
• CPC Class Codes: C07C 255/60 at least one of the singly-bound nitrogen atoms being acylated
• CPC Class Codes: C07C 281/02 : Compounds containing any of the groups , e.g. carbazates
• CPC Class Codes: C07C 323/09 : having sulfur atoms of thio groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
• CPC Class Codes: C07C 43/1742 : with halogen atoms bound to the aromatic rings
• CPC Class Codes: C07C 43/1745 : having more than one ether bound
• CPC Class Codes: C07D 261/04 : having one double bond between ring members or between a ring member and a non-ring member
• CPC Class Codes: C07D 261/16 : Benzene-sulfonamido isoxazoles
• CPC Class Codes: C07D 413/04 : directly linked by a ring-member-to-ring-member bond
• CPC Class Codes: C07D 413/06 : linked by a carbon chain containing only aliphatic carbon atoms
• CPC Class Codes: C07D 413/12 : linked by a chain containing hetero atoms as chain links
• CPC Class Codes: C07D 413/14 : containing three or more hetero rings
• CPC Class Codes: C07D 417/06 : linked by a carbon chain containing only aliphatic carbon atoms
• CPC Class Codes: C07D 417/12 : linked by a chain containing hetero atoms as chain links
• CPC Class Codes: C07F 7/0812 : comprising a heterocyclic ring

Abstract

An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof:

wherein A¹, A² and A³ independently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., X is halogen atom, C₁-C₆haloalkyl, etc., Y is halogen atom, C₁-C₆alkyl, etc., R¹ is C₁-C₁₂alkyl arbitrarily substituted with R¹⁶, C₃-C₂alkenyl, arbitrarily substituted with R¹⁶ is oxygen atom or sulfur atom, —N(R²⁰)R¹⁹, etc., R² is hydrogen atom, C₁-C₄alkoxy C₁-C₆alkyl, etc., R³ is C₁-C₆haloalkyl, etc., R¹⁶ is halogen atom, cyano, phenyl substituted with (Z)_p1, D-1 to D-60, E-1 to E-49, etc., R¹⁹ is phenyl, phenyl substituted with (Z)_p1, etc., R²⁰ is hydrogen atom, C₁-C₆alkyl, etc., Z is halogen atom, nitro, C₁-C₄alkoxy, etc., D-1 to D-60 are 5- or 6-membered aromatic heterocyclic rings, E-1 to E-49 are 5- or 6-membered saturated heterocyclic rings, m is an integer of 0 to 5, n is an integer of 0 to 4, p1 is an integer of 1 to 5. The pesticide containing these compounds.

Claims

1. An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof:

2. The isoxazoline-substituted benzamide compound or the salt thereof according to claim 1, wherein

G is a benzene ring;

X is halogen atom, cyano, nitro, —

SF₅, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, C₃-C₈cycloalkyl, C₃-C₈cycloalkyl arbitrarily substituted with R⁴, C₂-C₆alkenyl, C₂-C₆alkenyl arbitrarily substituted with R⁴, C₂-C₆alkynyl, C₂-C₆alkynyl arbitrarily substituted with R⁴, —

OH, —

OR⁵, —

OSO₂R⁵, —

S(O)_rR⁵, —

C(O)OR⁹, —

C(O)SR⁹, —

C(O)NHR¹⁰, —

C(O)N(R¹⁰)R⁹, —

C(S)OR⁹, —

C(S)SR⁹, —

C(S)NHR¹⁰, —

C(S)N(R¹⁰)R⁹, —

CH═

NOR¹¹, —

C(R⁹)═

NOR¹¹, —

S(O)₂NHR¹⁰, —

S(O)₂N(R¹⁰)R⁹, —

Si(R¹³)(R¹⁴)R¹², phenyl, phenyl substituted with (Z)_p1, D-1 to D-46, E-1 to E-28, E-32 to E-38 or E-43 to E-45, when m is an integer of 2 or more, each X may be identical with or different from each other, further, when two Xs are adjacent, the adjacent two Xs may form 5-membered or 6-membered ring together with carbon atoms to which the two Xs are bonded by forming —

CH₂CH₂CH₂—

, —

CH₂CH₂O—

, —

CH₂OCH₂—

, —

OCH₂O—

, —

CH₂CH₂S—

, —

CH₂SCH₂—

, —

CH₂CH₂CH₂CH₂—

, —

CH₂CH₂CH₂O—

, —

CH₂CH₂OCH₂—

, —

CH₂OCH₂O—

, —

OCH₂CH₂O—

, —

OCH₂CH₂S—

or —

CH═

CHCH═

CH—

, in this case, hydrogen atoms bonded to each carbon atom forming the ring may be arbitrarily substituted with halogen atom, C₁-C₄alkyl or C₁-C₄haloalkyl,

Y is halogen atom, cyano, nitro, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, —

OR⁵, —

OSO₂R⁵, —

S(O)_rR⁵, —

NHR⁷, —

N(R⁷)R⁶, —

N═

CHOR⁸, —

N═

C(R⁹)OR⁸, —

C(O)NHR¹⁰, —

C(O)N(R¹⁰)R⁹, —

C(S)NHR¹⁰, —

C(S)N(R¹⁰)R⁹, phenyl, phenyl substituted with (Z)_p1, D-1 to D-24, D-30 to D-38 or D-43 to D-46, when n is an integer of 2 or more, each Y may be identical with or different from each other,

further, when two Ys are adjacent, the adjacent two Ys may form 5-membered or 6-membered ring together with carbon atoms to which the two Ys are bonded by forming —

CH₂CH₂CH₂—

, —

CH₂CH₂O—

, —

CH₂OCH₂—

, —

OCH₂O—

, —

CH₂CH₂CH₂CH₂—

, —

CH₂CH₂CH₂O—

, —

CH₂CH₂OCH₂—

, —

CH₂OCH₂O—

, —

OCH₂CH₂O—

, —

OCH═

N—

or —

SCH═

N—

, in this case, hydrogen atoms bonded to each carbon atom forming the ring may be arbitrarily substituted with halogen atom, C₁-C₄alkyl or C₁-C₄haloalkyl,

R¹ is C₁-C₈alkyl, C₁-C₈alkyl arbitrarily substituted with R¹⁶, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₃-C₈alkenyl, C₃-C₈haloalkenyl, phenyl C₃-C₆alkenyl, phenyl C₃-C₆alkenyl substituted with (Z)_p1, C₃-C₈alkynyl, C₃-C₈haloalkynyl, phenyl C₃-C₆alkynyl, phenyl C₃-C₆alkynyl substituted with (Z)_p1, C₁-C₈alkoxy, —

N(R²⁰)R¹⁹, —

N═

CHR^19b, —

N═

C(R^19b)R^19a, —

C(O)N(R¹⁰)R⁹, —

C(S)N(R¹⁰)R⁹, —

C(═

NR¹¹)OR⁹, —

C(═

NR¹¹)SR⁹, —

C(═

NR¹¹)N(R¹⁰)R⁹, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-6 to D-18, D-21 to D-23, D-26 to D-40, D-42, D-45 to D-46, E-4 to E-9, E-23 to E-28, E-34 or E-45,

R² is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄haloalkoxy C₁-C₄alkyl, benzyloxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₁-C₄haloalkylthio C₁-C₄alkyl, C₁-C₄alkylsulfonyl C₁-C₄alkyl, C₁-C₄haloalkylsulfonyl C₁-C₄alkyl, phenylthio C_1-C4alkyl, phenylthio C₁-C₄alkyl substituted with (Z)_p1, cyano C₁-C₆alkyl, nitro C₁-C₆alkyl, C₁-C₄alkylcarbonyl C₁-C₄alkyl, C₁-C₄alkoxycarbonyl C₁-C₄alkyl, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, —

SR⁹, —

S(O)₂R⁹, —

SN(R¹⁸)R¹⁷, —

OH, —

OR¹⁹, —

NHR²⁰, —

N(R²⁰)R¹⁹, —

N═

CHR^19b, —

N═

C(R^19b)R^19a, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹ or —

C(S)SR⁹;

or R¹ and R² together form ═

C(R^2a)R^1a, and further R¹ and R² together may form 3- to 5-membered ring together with the nitrogen atom bonding them by forming C₂ to C₄ alkylene chain, in this case, the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and may be arbitrarily substituted with C₁-C₆alkyl, formyl, C₁-C₆alkylcarbonyl or C₁-C₆alkoxycarbonyl,

R^1a and R^2a together may form 5- or 6-membered ring together with the carbon atom bonding them by forming C₄ or C₅ alkylene chain or C₄ or C₅ alkenylene chain, in this case, the alkylene chain and the alkenylene chain may contain one to three oxygen atoms or sulfur atoms, or R^1a and R^2a together may form a 5-membered ring together with the carbon atom bonding them by forming C₄ alkylene chain or C₄ alkenylene chain, in this case, the alkylene chain and the alkenylene chain may contain one to three nitrogen atoms, and either ring may be arbitrarily substituted with halogen atom or C₁-C₆alkyl,

R³ is cyano, C₁-C₆alkyl arbitrarily substituted with R⁴, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, —

OR⁵, —

S(O)_rR⁵, —

N(R¹⁰)R⁹, —

C(O)OR⁹, C(O)SR⁹, —

C(O)NHR¹⁰, —

C(O)N(R¹⁰)R⁹, —

C(S)OR⁹, —

C(S)SR⁹, —

C(S)NHR¹⁰, —

C(S)N(R¹⁰)R⁹, —

CH═

NOR¹¹, —

C(R⁹)═

NOR¹¹, —

Si(R¹³)(R¹⁴)R¹², phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-13, D-15 to D-23, D-25 to D-37, D-39, D-40, D-42, D-45 to D-46 or E-4 to E-7, E-23 to E-27 or E-28;

R⁴ is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, —

OH, —

OR⁵, —

S(O)_rR⁵, —

N(R¹⁰)R⁹, —

N(R¹⁰)C(O)R⁹, —

N(R¹⁰)C(O)OR⁹, —

N(R¹⁰)C(O)SR⁹, —

N(R¹⁰)C(S)OR⁹, —

N(R¹⁰)C(S)SR⁹, —

N(R¹⁰)S(O)₂R⁹, —

Si(R¹³)(R¹⁴ )R¹², phenyl, phenyl substituted with (Z)_p1, D-1 to D-5, D-8 to D-38, D-41, D-43 or D-44;

R⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₃haloalkoxy C₁-C₃haloalkyl, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₂-C₆alkenyl, C₂-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-7, D-9, D-15 to D-23, D-30 to D-35, E-3 to E-9, E-23 to E-27 or E-28

R⁶ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, —

S(O)₂R⁹, —

CHO, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹ or —

C(S)SR⁹;

R⁷ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl;

R⁸ is C₁-C₆alkyl;

R⁹ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₆alkoxy C₁-C₄alkyl, C₁-C₆alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-6 to D-35 or D-38;

R¹⁰ is hydrogen atom or C₁-C₆alkyl, or R¹⁰ together with R⁹ may form a 5-membered ring with the nitrogen atom bonding them by forming C₄alkylene chain, in this case, the alkylene chain may contain oxygen atom or sulfur atom;

R¹¹ is C₁-C₆alkyl, C₁-C₆haloalkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, phenyl or phenyl substituted with (Z)_p1, or R¹¹ together with R⁹ may form 5- or 6-membered ring with the atom bonding them by forming C₂-C₃alkylene chain, in this case, the alkylene chain may be arbitrarily substituted with C₁-C₆alkyl;

R¹² is C₁-C₆alkyl, phenyl or phenyl substituted with (Z)_p1;

R¹³ and R¹⁴ independently of each other are C₁-C₆alkyl;

R¹⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, phenyl or phenyl substituted with (Z)_p1;

R¹⁶ is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, —

OR²⁵, —

N(R²⁶)R²⁵, —

SH, —

S(O)_rR²⁷, —

SO₂NHR²⁹, —

SO₂N(R²⁹)R²⁸, —

CHO, —

C(O)R²⁸, —

C(C)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(O)N(R²⁹)OR²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²⁸, —

C(R³¹)═

NOH, —

C(R³¹)═

NOR³⁰, —

C(═

NR³¹)OR³⁰, —

C(═

NR³¹)SR³⁰, —

C(═

NR³¹)N(R²⁹)R³⁰, —

C(═

NOR³¹)NHR²⁹, —

C(═

NOR³¹)N(R²⁹)R³⁰, —

Si(R¹³)(R¹⁴)R¹² phenyl, phenyl substituted with (Z)_p1, D-1 to D-46, E-1 to E-28, E-32 to E-38, E-43 to E-45 or M-1 to M-11;

R¹⁷ is C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₆alkoxycarbonyl C₁-C₄alkyl, phenyl

C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1 or C₁-C₆alkoxycarbonyl;

R¹⁸ is C₁-C₆alkyl, phenyl C₁-C₄alkyl or phenyl C₁-C₄alkyl substituted with (Z)_p1, or

R¹⁸ together with R¹⁷ may form a 5-membered ring with the nitrogen atom bonding them by forming C₄alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom, and may be arbitrarily substituted with methyl or methoxy;

R¹⁹ is C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R¹⁶, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, —

CHO, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²⁸, —

S(O)₂R²⁸, —

S(O)₂NHR²⁹, —

S(O)₂N(R²⁹)R²⁸, phenyl, phenyl substituted with (Z)_p1, D-1 to D-13, D-15 to D-25, D-30 to D-37, D-39, D-40, D-42, D-45 to D-46, E-5, E-7, E-9, E-24, E-25, E-27 or E-28;

R^19a is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-10, D-15 to D-23, E-4 to E-7, E-23 to E-27 or E-28;

R^19b is hydrogen atom or C₁-C₆alkyl, or R^19a together with R^19b may form 5- or 6-membered ring with the carbon atom bonding them by forming C₄ or C₅alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom;

R²⁰ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₁-C₄alkoxycarbonyl C₁-C₄alkyl, C₂-C₆alkenyl, C₃-C₆alkynyl, —

CHO, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹, —

C(S)SR⁹ or C₁-C₆alkylsulfonyl;

R²² is halogen atom, cyano, C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₆alkoxy, C₁-C₆alkoxycarbonyl, —

C(O)NH₂ or —

C(S)N₂, when q1, q2, q3 or q4 is an integer of 2 or more, each R²² may be identical with or different from each other, further in case where two R²²s are present on the same carbon atom, the two R²²s together may form oxo, thioxo, imino, C₁-C₆alkylimino, C₁-C₆alkoxyimino or C₁-C₆alkylidene;

R²³ is hydrogen atom, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R³², C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, —

OH, benzyloxy, —

CHO, —

C(O)R³³, —

C(O)OR³³, —

C(O)SR³³, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, —

S(O)₂R³³, phenyl, phenyl substituted with (Z)_p1 or D-5;

R²⁵ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₆alkenyl, C₃-C₆alkynyl, —

CHO, —

C(O)R³³, —

C(O)OR³³, —

C(O)SR³³, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, —

C(S)R³³, —

C(S)OR³³, —

C(S)SR³³, —

C(S)NHR³⁴, —

C(S)N(R³⁴)R³³, —

S(O)₂R³³, —

S(O)₂N(R³⁴)R³³, di(C₁-C₆alkyl)phosphoryl, di(C₁-C₆alkyl)thiophosphoryl, tri(C₁-C₄alkyl)silyl, phenyl or phenyl substituted with (Z)_p1;

R²⁶ is hydrogen atom, C₁-C₆alkyl, C₃-C₆alkenyl, C₃-C₆alkynyl or C₁-C₆alkoxy, or R²⁶ together with R²⁵ may form 4- to 5-membered ring with the nitrogen atom bonding them by forming C₃-C₄ alkylene chain, in this case, the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and may substituted with C₁-C₆alkyl, oxo or thioxo;

R²⁷ is C₁-C₆alklyl, C₁-C₆haloalkyl, hydroxy C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₁-C₄alkylcarbonyl C₁-C₄alkyl, C₁-C₄alkoxycarbonyl C₁-C₄alkyl, di(C₁-C₄alkyl)aminocarbonyl C₁-C₄alkyl, tri(C₁-C₄alkyl)silyl C₁-C₄alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₆alkenyl, C₃-C₆alkynyl, C₁-C₆alkylcarbonyl, C₁-C₆alkylthio, phenylthio, phenylthio substituted with (Z)_p1, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, —

C(S)NHR³⁴, —

C(S)N(R³⁴)R³³, phenyl, phenyl substituted with (Z)_p1, D-21 or D-35;

R²⁸ is C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R³², C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, phenyl, phenyl substituted with (Z)_p1, D-1 to D-46 or E-1 to E-28, E-32 to E-38, or E-43 to E-545;

R²⁹ is hydrogen atom, C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆alkenyl or C₃-C₆alkynyl, or R²⁹ together with R²⁸ may form 3- to 5-membered ring with the nitrogen atom bonding them by forming C₂-C₄ alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom;

R³⁰ is C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, tri(C₁-C₆alkyl)silyl C₁-C₄alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₈alkenyl, C₃-C₈haloalkenyl, C₃-C₈alkynyl or C₃-C₈haloalkynyl;

R³¹ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl or C₃-C₆cycloalkyl, or R³¹ together with R³⁰ may form 5- or 6-membered ring with the atom bonding them by forming C₂-C₃alkylene chain, in this case, the alkylene chain may be arbitrarily substituted with C₁-C₆alkyl;

R³² is halogen atom, cyano, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, —

OR³³, —

OC(O)R³³, —

OC(O)NHR³³, —

OC(O)N(R³⁴)R³³, —

S(O)_rR³³, —

SC(O)R³³, —

SC(O)NHR³³, —

SC(O)N(R³⁴)R³³, —

N(R³⁴)CHO, —

N(R³⁴)C(O)R³³, —

N(R³⁴)C(O)OR³³, —

C(O)OR³³, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, phenyl, phenyl substituted with (Z)_p1, D-1 to D-46 or E-1 to E-28, E-32 to E-38, or E-43 to E-45;

R³³ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄haloalkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₁-C₄haloalkylthio C₁-C₄alkyl, C₁-C₄alkylsulfonyl C₁-C₄alkyl, C₁-C₄haloalkylsulfonyl C₁-C₄alkyl, cyano C₁-C₆alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-13, D-15 to D-18, D-21, D-29 to D-37, E-5, E-7, E-9, E-24, E-25, E-27, E-28 or E-34;

R³⁴ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl, or R³⁴ together with R³³ may form 3- to 5-membered ring with the nitrogen atom bonding them by forming C₂-C₅alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom.

3. The isoxazoline-substituted benzamide compound or the salt thereof according to claim 2, wherein

G is a benzene ring

X is halogen atom, cyano, nitro, —

SF₅, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₂-C₆alkenyl, C₂-C₆haloalkenyl, C₂-C₆alkynyl, C₂-C₆haloalkynyl, —

OR⁵, —

OSO₂R⁵, —

S(O)_rR⁵, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹, —

C(S)SR⁹, —

C(S)NHR¹⁰, —

C(S)N(R¹⁰)R⁹, —

CH═

NOR¹¹, —

C(R⁹)═

NOR¹¹, —

Si(R¹³)(R¹⁴)R¹², E-10, E-12, E-18, E-32, E-35 or E-43, when m is 2 or 3, each X may be identical with or different from each other,

further, when two Xs are adjacent, the adjacent two Xs may form 5-membered or 6- membered ring together with carbon atoms to which the two Xs are bonded by forming —

CF₂OCF₂—

, —

OCF₂O—

, —

CF₂OCF₂O—

or —

OCF₂CF₂O—

;

Y is halogen atom, cyano, nitro, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, —

OR⁵, —

OSO₂R⁵, —

S(O)_rR⁵, —

NHR⁷, —

N(R⁷)R⁶, —

N═

C(R⁹)OR⁸, —

C(O)NH₂ or —

C(S)NH₂, when n is 2 or 3, each Y may be identical with or different from each other;

R¹ is C₁-C₈alkyl, C₁-C₈alkyl arbitrarily substituted with R¹⁶, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₃-C₈alkenyl, C₃-C₈haloalkenyl, C₃-C₈alkynyl, C₃-C₈haloalkynyl, —

N(R²⁰)R¹⁹, —

C(O)N(R¹⁰)R⁹, —

C(S)N(R¹⁰)R⁹, phenyl substituted with (Z)_p1, D-8 to D-18, D-21 to D-24, D-26 to D-40, D-42, D-45 to D-46, E-4, E-5, E-7, E-8, E-9, E-23 to E-25, E-27, E- 28 or E-34;

R² is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, —

OH, C₁-C₆alkoxy, C₁-C₆alkylcarbonyloxy, C₁-C₆alkoxycarbonyloxy, C₁-C₆alkylsulfonyloxy, C₁-C₆haloalkylthio, phenylthio, phenylthio substituted with (Z)_p1, C₁-C₆alkylsulfonyl, —

SN(R¹⁸)R¹⁷, —

NHR²⁰, —

N═

CHR^19b, —

N═

C(R^19b)R^19a, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹ or —

C(S)SR⁹, or R² together with R¹ may form 3- to 5-membered ring with the nitrogen atom bonding them by forming C₂-C₄ alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom;

R³ is C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₃-C₆halocycloalkyl C₁-C₄alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄haloalkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₁-C₄alkylsulfinyl C₁-C₄alkyl, C₁-C₄alkylsulfonyl C₁-C₄alkyl, C₁-C₄haloalkylthio C₁-C₄alkyl, C₁-C₄haloalkylsulfinyl C₁-C₄alkyl, C₁-C₄haloalkylsulfonyl C₁-C₄alkyl, cyano C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄haloalkyl, C₁-C₄haloalkoxy C₁-C₄haloalkyl, C₁-C₄alkylthio C₁-C₄haloalkyl, C₁-C₄alkylsulfinyl C₁-C₄haloalkyl, C₁-C₄alkylsulfonyl C₁-C₄haloalkyl, C₁-C₄haloalkylthio C₁-C₄haloalkyl, C₁-C₄haloalkylsulfinyl C₁-C₄haloalkyl, C₁-C₄haloalkylsulfonyl C₁-C₄haloalkyl, cyano C₁-C₆haloalkyl, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, E-4 to E-7, E-23 to E-27 or E-28;

R⁴ is halogen atom, cyano, —

OH, C₁-C₆alkoxy, C₁-C₆haloalkoxy, C₁-C₆alkylthio, C₁-C₆haloalkylthio, C₁-C₆alkylsulfinyl, C₁-C₆haloalkylsulfinyl, C₁-C₆alkylsulfonyl, C₁-C₆haloalkylsulfonyl or tri(C₁-C₆alkyl)silyl;

R⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₃haloalkoxy C₁-C₃haloalkyl, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₂-C₆alkenyl, C₂-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, E-4 to E-9, E-23 to E-27 or E-28;

R⁶ is C₁-C₆alkyl, C₁-C₆haloalkyl, —

S(O)₂R⁹, —

CHO, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹ or —

C(S)SR⁹;

R⁷ is hydrogen atom, C₁-C₆alkyl or C₁-C₆haloalkyl;

R⁹ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₆alkoxy C₁-C₄alkyl, C₁-C₆alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, phenyl C₁-C₄alkyl, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl;

R¹⁰ is hydrogen atom or C₁-C₆alkyl, or R¹⁰ together with R⁹ may form a 5-membered ring with the nitrogen atom bonding them by forming C₄ alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom;

R¹¹ is C₁-C₆alkyl or C₁-C₆haloalkyl, or R¹¹ together with R⁹ may form 5- or 6-membered ring with the atom bonding them by forming C₂ or C₃alkylene chain, in this case, the alkylene chain may be arbitrarily substituted with C₁-C₆alkyl;

R¹⁵ is C₁-C₆alkyl or C₁-C₆haloalkyl;

R¹⁶ is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, —

OR²⁵, —

N(R²⁶)R²⁵, —

S(O)_rR²⁷, —

SO₂NHR²⁹, —

SO₂N(R²⁹)R²⁸, —

CHO, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(O)N(R²⁹)OR²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²⁸, —

C(R³¹)═

NOH, —

C(R³¹)═

NOR³⁰, —

C(═

NR³¹)OR³⁰, —

C(═

NR³¹)SR³⁰, —

C(═

NR³¹)N(R²⁹)R³⁰, —

C(═

NOR³¹)NHR<sup>29, —

C(═

NOR31</sup>)N(R²⁹)R³⁰, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-42, E-4 to E-12, E-14, E-16 to E-19, E-21 to E-23, E-26 to E-28, E-43 to E-45, M-2, M-3, M-5 or M-8 to M-10;

R¹⁷ is C₁-C₆alkyl, C₁-C₆alkoxycarbonyl C₁-C₄alkyl or C₁-C₆alkoxycarbonyl;

R¹⁸ is C₁-C₆alkyl or benzyl;

R¹⁹ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₆alkyl, phenyl C₁-C₆alkyl, phenyl C₁-C₆alkyl substituted with (Z)_p1, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²⁸, C₁-C₆alkylsulfonyl, C₁-C₆haloalkylsulfonyl, phenylsulfonyl, phenylsulfonyl substituted with (Z)_p1, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-18, D-21, D-25 or D-30 to D-35;

R^19a is C₁-C₆alkyl;

R^19b is hydrogen atom or C₁-C₆alkyl;

R²⁰ is hydrogen atom, C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, —

CHO, C₁-C₆alkylcarbonyl, C₁-C₆haloalkylcarbonyl, C₁-C₆alkoxycarbonyl, C₁-C₆haloalkoxycarbonyl or C₁-C₆alkylsulfonyl;

R²² is C₁-C₄alkyl or C₁-C₄haloalkyl, or two R²²s present on the same carbon atom may together form oxo, or thioxo;

R²³ is hydrogen atom, C₁-C₆alkyl, —

CHO, C₁-C₆alkylcarbonyl, C₁-C₆haloalkylcarbonyl, C₁-C₆alkoxycarbonyl, C₁-C₆alkylsulfonyl or C₁-C₆haloalkylsulfonyl,

R²⁵ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, —

C(O)R³³, —

C(O)OR³³, —

C(O)SR³³, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, —

C(S)R³³, —

C(S)OR³³, —

C(S)SR³³, —

C(S)NHR³⁴, —

C(S)N(R³⁴)R³³, —

S(O)₂R³³, —

S(O)₂N(R³⁴)R³³, di(C₁-C₆alkyl)thiophosphoryl, phenyl or phenyl substituted with (Z)_p1;

R²⁶ is hydrogen atom or C₁-C₆alkyl, or R²⁶ together with R²⁵ may form 4- to 5-membered ring with the nitrogen atom bonding them by forming C₃-C₄ alkylene chain, in this case, the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and may be substituted with C₁-C₆alkyl, oxo or thioxo;

R²⁷ is C₁-C₆alkyl, C₁-C₆haloalkyl, tri(C₁-C₄alkyl)silyl C₁-₄alkyl, C₁-C₆alkylthio, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, —

C(S)NHR³⁴, —

C(S)N(R³⁴)R³³, phenyl or phenyl substituted with (Z)_p1;

R²⁸ is C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R³², C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, phenyl or phenyl substituted with (Z)_p1;

R²⁹ is hydrogen atom, C₁-C₆alkyl, C₃-C₆alkenyl or C₃-C₆alkynyl, or R²⁹ together with R²⁸ may form 3- to 5-membered ring with the nitrogen atom bonding them by forming C₂-C₄ alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom;

R³⁰ is C₁-C₆alkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₈alkenyl or C₃-C₈alkynyl;

R³¹ is hydrogen atom or C₁-C₆alkyl, or R³¹ together with R³⁰ may form 5- or 6-membered ring with the atom bonding them by forming C₂ or C₃alkylene chain, in this case, the alkylene chain may be arbitrarily substituted with C₁-C₆alkyl;

R³² is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₁-C₄alkoxy, C₁-C₄haloalkoxy, C₁-C₄alkylthio, C₁-C₄haloalkylthio, C₁-C₄alkoxycarbonyl, —

C(O)NH₂, C₁-C₄alkylaminocarbonyl, di(C₁-C₄alkyl)aminocarbonyl, phenyl or phenyl substituted with (Z)_p1, R³³ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₁-C₄alkylsulfonyl C₁-C₄alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, phenyl or phenyl substituted with (Z)_p1;

R³⁴ is hydrogen atom or C₁-C₆alkyl;

m is an integer of 1 to 3;

n is an integer of 0 to 2;

q1 is 0;

q2 is an integer of 0 to 3;

q3 is an integer of 0 to 2; and

q4 is an integer of 0 to 2.

4. The isoxazoline-substituted benzamide compound or the salt thereof according to claim 3, wherein

A¹ is carbon;

A² and A³ are carbon atom;

G is a benzene ring;

X is halogen atom, cyano, nitro, —

SF₅, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₂-C₆alkenyl, C₂-C₆haloalkenyl, C₂-C₆alkynyl, C₂-C₆haloalkynyl, —

OR⁵, —

OSO₂R⁵, —

S(O)^rR⁵ or tri(C₁-C₆alkyl)silyl, when m is 2 or 3, each X may be identical with or different from each other,

further, when two Xs are adjacent, the adjacent two Xs may form 5-membered or 6-membered ring together with carbon atoms to which the two Xs are bonded by forming —

CF₂OCF₂—

, —

OCF₂O—

, —

CF₂OCF₂O—

or —

OCF₂CF₂O—

;

Y is halogen atom, cyano, nitro, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, —

OR⁵, —

OSO₂R⁵, —

S(O)_rR⁵, —

NHR⁷, —

N(R⁷)R⁶, —

C(O)NH₂ or —

C(S)NH₂, when n is 2 or 3, each Y may be identical with or different from each other;

R¹ is C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R¹⁶, C₃-C₈cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, —

N(R²⁰)R¹⁹, —

C(O)N(R¹⁰)R⁹, —

C(S)N(R¹⁰)R⁹, phenyl substituted with (Z)_p1, D-8, D-10, D-11, D-13 to D-15, D-17, D-18, D-21 to D-23, D-26 to D-37, D-39, D-40, D-42, D-45, E-4, E-5, E-7 or E-9;

R² is hydrogen atom, C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, —

OH, C₁-C₆alkylcarbonyloxy, C₁-C₆alkylsulfonyloxy, —

NH₂, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹ or —

C(S)SR⁹;

R³ is C₁-C₆haloalkyl, C₁-C₄alkoxy C₁-C₄haloalkyl, C₁-C₄haloalkoxy C₁-C₄haloalkyl, C₁-C₄alkylthio C₁-C₄haloalkyl, C₁-C₄haloalkylthio C₁-C₄haloalkyl, cyano C₁-C₆haloalkyl or C₃-C₈halocycloalkyl;

R⁴ is halogen atom, cyano, —

OH, C₁-C₆alkoxy, C₁-C₆haloalkoxy, C₁-C₆alkylthio, C₁-C₆haloalkylthio, C₁-C₆alkylsulfinyl, C₁-C₆haloalkylsulfinyl, C₁-C₆alkylsulfonyl, C₁-C₆haloalkylsulfonyl or tri(C₁-C₆alkyl)silyl;

R⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₃haloalkoxy C₁-C₃haloalkyl, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₂-C₆alkenyl, C₂-C₆haloalkenyl, C₃-C₆alkynyl or C₃-C₆haloalkynyl;

R⁶ is C₁-C₆alkyl, C₁-C₆haloalkyl, —

CHO, C₁-C₆alkylcarbonyl, C₁-C₆haloalkylcarbonyl, C₃-C₆cycloalkylcarbonyl, C₃-C₆halocycloalkylcarbonyl, C₁-C₆alkoxycarbonyl, C₁-C₆haloalkoxycarbonyl, C₁-C₆alkylthiocarbonyl, C₁-C₆alkoxythiocarbonyl, C₁-C₆alkyldithiocarbonyl, C₁-C₆alkylsulfonyl or C₁-C₆haloalkylsulfonyl;

R⁷ is hydrogen atom or C₁-C₆alkyl;

R⁹ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₆alkoxy C₁-C₄alkyl, C₁-C₆alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₈cycloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl;

R¹⁶ is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, —

OR²⁵, —

N(R²⁶)R²⁵, —

S(O)_rR²⁷, —

SO₂NHR²⁹, —

SO₂N(R²⁹)R²⁸, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(O)N(R²⁹)OR²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²⁸, —

C(R³¹)═

NOH, —

C(R³¹)═

NOR³⁰, —

C(═

NR³¹)OR³⁰, —

C(═

NR³¹)SR³⁰, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-38, E-4 to E-12, E-18, E-19, E-32, E-35, E-43, M-2, M-3, M-5, M-8, M-9 or M-10;

R¹⁹ is C₁-C₆haloalkyl, C₃-C₆cycloalkyl, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²⁸, phenyl, phenyl substituted with (Z)_p1, D-3, D-4, D-21;

R²⁰ is hydrogen atom, C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, —

CHO, C₁-C₆alkylcarbonyl, C₁-C₆alkoxycarbonyl or C₁-C₆alkylsulfonyl;

R²⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₆alkylcarbonyl, C₁-C₆alkoxycarbonyl, C₁-C₆alkylaminocarbonyl, di(C₁-C₆alkyl)aminocarbonyl or C₁-C₆alkylsulfonyl;

R²⁶ is hydrogen atom or C₁-C₆alkyl;

R²⁷ is C₁-C₆alkyl, C₁-C₆haloalkyl or tri(C₁-C₄alkyl)silyl C₁-C₄alkyl;

R²⁸ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alky, cyano C₁-C₆alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, phenyl or phenyl substituted with (Z)_p1;

R²⁹ is hydrogen atom, C₁-C₆alkyl, C₃-C₆alkenyl or C₃-C₆alkynyl;

R³⁰ is C₁-C₆alkyl or C₃-C₆cycloalkyl C₁-C₄alkyl;

R³¹ is hydrogen atom or C₁-C₆alkyl, or R³¹ together with R³⁰ may form 5- or 6-membered ring with the atom bonding them by forming C₂ or C₃alkylene chain.

5. The isoxazoline-substituted benzamide compound or the salt thereof according to claim 4, wherein

X is halogen atom, cyano, nitro, —

SF₅, C₁-C₆alkyl, C₁-C₆haloalkyl, hydroxy C₁-C₆haloalkyl, C₁-C₆alkoxy C₁-C₆haloalkyl, C₁-C₆haloalkoxy C₁-C₆haloalkyl, C₃-C₈halocycloalkyl, —

OR⁵, —

OSO₂R⁵ or —

S(O)_rR⁵, when m is 2 or 3, each X may be identical with or different from each other;

Y is halogen atom, cyano, nitro, C₁-C₄alkyl, C₁-C₄haloalkyl, C₁-C₄alkoxy, C₁-C₄haloalkoxy, C₁-C₆alkylthio, C₁-C₆haloalkylthio, C₁-C₆alkylsulfonyl, C₁-C₆-C₆haloalkylsulfonyl, —

NHR⁷ or —

N(R⁷)R⁶;

R¹ is C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R¹⁶, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₈haloalkenyl, C₃-C₆alkynyl, —

N(R²⁰)R¹⁹, D-8, D-10, D-13 to D-15, D-18, D-21, D-34, D-35;

R² is hydrogen atom, C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆alkynyl, —

C(O)R⁹ or —

C(O)OR⁹;

R³ is C₁-C₆haloalkyl or C₃-C₈halocycloalkyl;

R⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl or C₁-C₃haloalkoxy C₁-C₃haloalkyl;

R⁶ is C₁-C₆alkyl, —

CHO, C₁-C₆alkylcarbonyl, C₁-C₆haloalkylcarbonyl, C₁-C₆alkoxycarbonyl, C₁-C₆alkylthiocarbonyl, C₁-C₆alkoxythiocarbonyl, C₁-C₆alkyldithiocarbonyl, C₁-C₆alkylsulfonyl or C₁-C₆haloalkylsulfonyl;

R⁹ is C₁-C₆alkyl, C₁-C₆alkoxy C₁-C₄alkyl, C₁-C₆alkylthio C₁-C₄alkyl, C₃-C₈cycloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl;

R¹⁶ is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₁-C₆alkoxy, C₁-C₆haloalkoxy, C₁-C₆alkylthio, C₁-C₆haloalkylthio, C₁-C₆alkylsulfinyl, C₁-C₆haloalkylsulfinyl, C₁-C₆alkylsulfonyl, C₁-C₆haloalkylsulfonyl, C₁-C₆alkylcarbonyl, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(S)NH₂, —

C(R³¹)═

NOH, —

C(R³¹)═

NOR³⁰, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-38, E-4 to E-7, E-10, E-11 or E-32;

R¹⁹ is C₁-C₆haloalkyl, —

C(O)R²⁹, —

C(O)OR²⁸, phenyl, phenyl substituted with (Z)_p1, D-3, D-4, D-21;

R²⁰ is hydrogen atom or C₁-C₆alkyl;

R²⁸ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₃-C₆cycloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl;

R²⁹ is hydrogen atom or C₁-C₆alkyl;

R³⁰ is C₁-C₆alkyl;

R³¹ is hydrogen atom or C₁-C₆alkyl; and

n is an integer of 0 or 1.

6. A pesticide containing as an active ingredient one or more selected from isoxazoline-substituted benzamide compound and the salt thereof according to claim 1.

7. An agrochemical containing as an active ingredient one or more selected from isoxazoline-substituted benzamide compound and the salt thereof according to claim 1.

8. An endo- or ecto-parasiticide for mammals or birds containing as an active ingredient one or more selected from isoxazoline-substituted benzamide compound and the salt thereof according to claim 1.

9. An insecticide or acaricide containing as an active ingredient one or more selected from isoxazoline-substituted benzamide compound and the salt thereof according to claim 1.