Cardiac rhythm management system with arrhythmia classification and electrode selection

• US 7,664,549 B2
• Filed: 05/10/2005
• Issued: 02/16/2010
• Est. Priority Date: 12/20/2001
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Spinelli, Julio C., Stahmann, Jeffrey E., Zhu, Qingsheng, Kramer, Andrew P.
• Primary Examiner(s): Schaetzle; Kennedy J
• Application Number:
  US11/125,501
• Publication Number:
  US 20050203581A1
• Time in Patent Office: 1,743 Days
• Field of Search: 607/14
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/36843 Bi-ventricular stimulation

Abstract

A system, method, or device classifies an arrhythmia according to the temporal order in which a depolarization wave associated with a particular heart contraction is received at a plurality of electrodes. One or more antiarrhythmia therapies is mapped to each arrhythmia classification. When a particularly classified arrhythmia is detected, the correspondingly mapped therapy list is selected and an appropriate antiarrhythmia therapy delivered. In one example, the particular therapy delivered in response to an arrhythmia depends at least in part on its historical success in treating arrhythmias of that classification.

Claims

1. An implantable cardiac rhythm management device for coupling to a plurality of electrodes for association with a heart, the device including:

a cardiac signal detector circuit, for coupling to the electrodes;

an energy output circuit, coupled to at least one of the electrodes; and

a controller, coupled to the cardiac signal detector and the energy output circuit, the controller including;

an arrhythmia detector module, to detect an arrhythmia;

an arrhythmia classifier module, to classify the detected arrhythmia into an arrhythmia classification that specifies;

(a) a sequence in which a same heart contraction depolarization is received by at least three of the electrodes, wherein at least two electrodes are associated with different heart chambers, and (b) values of relative interelectrode time that the same heart contraction depolarization is received by the three electrodes;

a therapy map, providing an antiarrhythmia therapy corresponding to the arrhythmia classification, wherein an antiarrhythmia therapy is delivered according to an electrode sequence that is mapped to the relative interelectrode time; and

a control signal to be issued to the energy output circuit for delivering a selected antiarrhythmia therapy corresponding to an arrhythmia classification.

2. The device of claim 1, in which the arrhythmia classifier module classifies the detected arrhythmia into an arrhythmia classification that specifies:

(a) a sequence in which the heart contraction depolarization is received by a plurality of electrodes that are associated with different heart chambers and with the same heart chamber, and (b) values of relative interelectrode time at which the heart contraction depolarization is received by the electrodes that are associated with different heart chambers and with the same heart chamber.

3. The device of claim 1, in which the controller permits selecting the antiarrhythmia therapy corresponding to the arrhythmia classification, including selecting the antiarrhythmia therapy from a list of antiarrhythmia therapies that are mapped to the arrhythmia classification.

4. The device of claim 3, in which the controller permits selecting the antiarrhythmia therapy from the list based on a corresponding success estimate obtained from historical data about how successful a particular antiarrhythmia therapy has previously been in treating similarly classified arrhythmias.

5. The device of claim 4, in which the controller permits updating the success estimate after issuing the control signal and determining whether the delivered therapy was successful at treating the arrhythmia.

6. The device of claim 5, in which the controller permits escalating to a different antiarrhythmia therapy if the delivered therapy was unsuccessful at treating the arrhythmia.

7. The device of claim 4, in which the controller permits selecting the antiarrhythmia therapy from the list at least in part by factoring in an undesirability of a side effect of applying the antiarrhythmia therapy.

8. The device of claim 3, in which the controller permits selecting the antiarrhythmia therapy from the list at least in part by factoring in an undesirability of a side effect of applying the antiarrhythmia therapy.

9. The device of claim 1, in which the arrhythmia detector permits determining whether the delivered antiarrhythmia therapy is successful at treating the arrhythmia.

10. The device of claim 9, in which the controller permits updating the success estimate based on whether the delivered antiarrhythmia therapy was successful at treating the arrhythmia.

11. The device of claim 1, in which the arrhythmia detector permits determining whether the delivered antiarrhythmia therapy is successful at treating the arrhythmia, and the controller escalates to a higher-confidence antiarrhythmia therapy after a specified number of failures in treating the detected arrhythmia.

12. The device of claim 1, in which the arrhythmia classifier module is configured to again classify the detected arrhythmia after an antiarrhythmia therapy is delivered without successfully treating the arrhythmia.

13. A machine-assisted method including:

detecting an arrhythmia at a plurality of electrodes;

classifying a detected arrhythmia into an arrhythmia classification that specifies (a) a sequence in which a same heart contraction depolarization is received by at least three of the electrodes, wherein at least two electrodes are associated with different heart chambers, and (b) values of relative interelectrode time that the same heart contraction depolarization is received by the three electrodes;

selecting an antiarrhythmia therapy corresponding to an arrhythmia classification of the detected arrhythmia, wherein an antiarrhythmia therapy is delivered according to an electrode sequence determined using the relative electrode time; and

delivering a selected antiarrhythmia therapy by issuing a control signal to the energy output circuit.

14. The method of claim 13, in which the classifying comprises obtaining a classification specifying (a) a sequence in which the heart contraction depolarization is received by a plurality of electrodes that are associated with different heart chambers and with the same heart chamber, and (b) values of interelectrode time at which the heart contraction depolarization is received by the electrodes that are associated with different heart chambers and with the same heart chamber.

15. The method of claim 13, in which the selecting the antiarrhythmia therapy includes selecting the antiarrhythmia therapy using a corresponding success estimate obtained from historical data about how successful a particular antiarrhythmia therapy has previously been in treating similarly classified arrhythmias.

16. The method of claim 15, including updating the success estimate after issuing the control signal and determining whether the delivered therapy was successful at treating the arrhythmia.

17. The method of claim 16, including escalating to a different antiarrhythmia therapy if the delivered therapy was unsuccessful at treating the arrhythmia.

18. The method of claim 15, including updating the success estimate according to whether the delivered antiarrhythmia therapy successfully treated the arrhythmia.

19. The method of claim 13, in which the selecting the antiarrhythmia therapy includes factoring in an undesirability of a side effect of applying the antiarrhythmia therapy.

20. The method of claim 13, including determining whether the delivered antiarrhythmia therapy is successful at treating the arrhythmia.

21. The method of claim 13, including:

determining whether the delivered antiarrhythmia therapy was successful at treating the arrhythmia; and

escalating to a higher-confidence antiarrhythmia therapy after a specified number of failures in treating the detected arrhythmia.

22. The method of claim 13, including:

determining whether the delivered antiarrhythmia therapy was successful at treating the arrhythmia; and

again classifying the detected arrhythmia if the antiarrhythmia therapy was delivered without successfully treating the arrhythmia.

23. A machine-assisted method including:

detecting an arrhythmia at a plurality of electrodes;

classifying a detected arrhythmia into an arrhythmia classification that specifies first information that is indicative of a sequence in which a same heart contraction is received by at least three of the electrodes and second information that includes values of relative interelectrode time that a same heart contraction depolarization is received by the three electrodes;

selecting an antiarrhythmia therapy corresponding to an arrhythmia classification of the detected arrhythmia, the selecting including using a map listing a plurality of the arrhythmia classifications and respectively corresponding antiarrhythmia therapies, wherein an antiarrhythmia therapy is delivered according to an electrode sequence that is mapped to the values of relative interelectrode time; and

delivering a selected antiarrhythmia therapy by issuing a control signal to the energy output circuit.

24. The method of claim 23, wherein classifying a detected arrhythmia includes a classification that specifies third information, in which the third information includes information about a sequence in which the heart contraction depolarization is received by at least two of the electrodes.

25. The method of claim 24, in which the third information includes information about the sequence in which the heart contraction depolarization is received by at least two of the electrodes that are associated with the same heart chamber.

26. The method of claim 24, in which the second information includes a value of a difference between the times at which the heart contraction depolarization is received by the at least two electrodes.

27. The method of claim 23, in which the selecting the antiarrhythmia therapy includes selecting the antiarrhythmia therapy using a corresponding success estimate obtained from historical data about how successful a particular antiarrhythmia therapy has previously been in treating similarly classified arrhythmias.

28. The method of claim 23, including:

determining whether the delivered antiarrhythmia therapy was successful at treating the arrhythmia; and

again classifying the detected arrhythmia if the antiarrhythmia therapy was delivered without successfully treating the arrhythmia.