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Monomeric self-associating fusion polypeptides and therapeutic uses thereof

  • US 7,666,622 B2
  • Filed: 10/18/2006
  • Issued: 02/23/2010
  • Est. Priority Date: 10/19/2005
  • Status: Active Grant
First Claim
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1. A nucleic acid encoding monomeric fusion polypeptide R1-M-L-M, wherein R1 is a ligand-binding domain of an interleukin receptor capable of binding an interleukin target ligand, M is a self-associating component, and L is a linker, wherein the nucleic acid encodes a fusion polypeptide comprising the amino acid sequence of SEQ ID NO:

  • 16.

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