Determination of explosives including RDX
First Claim
1. A method for determination of an analyte, comprising:
- exposing a compound having a luminescence emission to a sample suspected of containing an analyte, wherein the analyte, if present, interacts with the compound to accept a hydride equivalent from the compound, causing a change in the luminescence emission of the compound;
wherein the compound has the structure,
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Abstract
The present invention provides sensors and methods for determination of an analyte. The analytes may be determined by monitoring, for example, a change in an optical signal of an emissive material upon exposure to an analyte. In some embodiments, the analyte and the emissive material may interact via a chemical reaction, or other chemical, biochemical or biological interaction (e.g., recognition), to form a new emissive species. In some cases, the present invention may be used for the detection of analytes such as explosives (e.g., RDX, PETN). Methods of the present invention may be advantageous in that the high sensitivity of luminescence (e.g., fluorescence) spectroscopy can allow for the reliable detection of small changes in luminescence intensity.
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Citations
26 Claims
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1. A method for determination of an analyte, comprising:
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exposing a compound having a luminescence emission to a sample suspected of containing an analyte, wherein the analyte, if present, interacts with the compound to accept a hydride equivalent from the compound, causing a change in the luminescence emission of the compound; wherein the compound has the structure, - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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Specification