Reinforced absorbable multilayered fabric for use in medical devices

• US 7,666,803 B2
• Filed: 10/17/2005
• Issued: 02/23/2010
• Est. Priority Date: 10/20/2004
• Status: Active Grant

• Current Assignee: Ethicon Incorporated (Johnson & Johnson)
• Original Assignee: Ethicon Incorporated (Johnson & Johnson)
• Inventors: Shetty, Dhanuraj S., Gorman, Anne Jessica, Kalirai, Simmi, Pendharkar, Sanyog Manohar
• Primary Examiner(s): TORRES VELAZQUEZ, NORCA LIZ
• Application Number:
  US11/252,120
• Publication Number:
  US 20060084338A1
• Time in Patent Office: 1,590 Days
• Field of Search: 442/268, 442/319, 442/123, 424/455, 424/445
• US Class Current: 442/268
• CPC Class Codes: A61F 13/00 Bandages or dressings radioactive dressings A61N5/1029; Absorbent pads
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2013/00604 Multilayer
• CPC Class Codes: A61F 2013/00927 with biological activity, e.g. enzymes for debriding wounds or others, collagen or growth factors
• CPC Class Codes: A61L 15/26 Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof A61L15/225 takes precedence
• CPC Class Codes: A61L 15/28 Polysaccharides or their derivatives A61L15/225 takes precedence
• CPC Class Codes: A61L 2430/06 for cartilage reconstruction, e.g. meniscus
• CPC Class Codes: A61L 2430/10 for reconstruction of tendons or ligaments
• CPC Class Codes: A61L 2430/24 for joint reconstruction
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/20 Polysaccharides
• CPC Class Codes: A61L 27/48 with macromolecular fillers
• CPC Class Codes: A61L 27/58 Materials at least partially resorbable by the body
• CPC Class Codes: A61L 31/042 Polysaccharides
• CPC Class Codes: A61L 31/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61P 17/02 for treating wounds, ulcers, burns, scars, keloids, or the like
• CPC Class Codes: B32B 2250/02 2 layers
• CPC Class Codes: B32B 2250/20 All layers being fibrous or filamentary
• CPC Class Codes: B32B 2262/0276 Polyester fibres
• CPC Class Codes: B32B 2262/04 Cellulosic plastic fibres, e.g. rayon
• CPC Class Codes: B32B 2262/06 : Vegetal fibres
• CPC Class Codes: B32B 2307/726 : Permeability to liquids, absorption
• CPC Class Codes: B32B 2459/00 : Nets, e.g. camouflage nets
• CPC Class Codes: B32B 2535/00 : Medical equipment, e.g. bandage, prostheses, catheter medical patches B32B2556/00
• CPC Class Codes: B32B 5/022 : Non-woven fabric
• CPC Class Codes: B32B 5/024 : Woven fabric
• CPC Class Codes: B32B 5/026 : Knitted fabric
• CPC Class Codes: B32B 5/06 : characterised by a fibrous or filamentary layer mechanically connected, e.g. by needling to another layer, e.g. of fibres, of paper
• CPC Class Codes: B32B 5/10 : characterised by a fibrous or filamentary layer reinforced with filaments
• CPC Class Codes: B32B 5/26 : another layer next to it also being fibrous or filamentary relative arrangement of fibres or filaments of different layers B32B5/12
• CPC Class Codes: B32B 9/04 : comprising such particular substance as the main or only constituent of a layer, which is next to another layer of the same or of a different material next to a glass layer B32B17/06; layered products with at least two ceramic layers composed mainly of ceramic B32B18/00
• CPC Class Codes: C08L 1/00 : Compositions of cellulose, modified cellulose or cellulose derivatives
• CPC Class Codes: C08L 1/04 : Oxycellulose; Hydrocellulose , e.g. microcrystalline cellulose
• CPC Class Codes: C08L 1/24 : Viscose
• CPC Class Codes: C08L 67/04 : Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence
• CPC Class Codes: D04H 1/435 : Polyesters
• CPC Class Codes: D04H 1/4374 : using different kinds of webs, e.g. by layering webs
• CPC Class Codes: Y10T 442/3707 : Woven fabric including a nonwoven fabric layer other than paper
• CPC Class Codes: Y10T 442/494 : Including a nonwoven fabric layer other than paper

Abstract

The present invention is directed to a multilayered fabric comprising a first absorbable nonwoven fabric and a second absorbable woven or knitted fabric.

Claims

1. A multilayered fabric comprising a first absorbable nonwoven fabric and a second absorbable woven or knitted fabric comprising oxidized polysaccharides.

2. The multilayered fabric of claim 1, where the first absorbable nonwoven fabric comprises fibers comprised of aliphatic polyester polymers or copolymers of one or more monomers selected from the group consisting of lactic acid, lactide (including L-, D-, meso and D, L mixtures), glycolic acid, glycolide, ε

-caprolactone, p-dioxanone, and trimethylene carbonate.

3. The multilayered fabric of claim 2, where the first absorbable nonwoven fabric comprises glycolide/lactide copolymer.

4. The multilayered fabric of claim 1, where the second absorbable woven or knitted fabric comprises oxidized cellulose.

5. The multilayered fabric of claim 4, where the second absorbable woven or knitted fabric comprises oxidized regenerated cellulose.

6. The multilayered fabric of claim 4, where the second absorbable woven or knitted fabric is an absorbable knitted fabric comprising oxidized regenerated cellulose.

7. The multilayered fabric of claim 3, where the first absorbable nonwoven fabric comprises staple having a length from about 0.75 to 2.5 inches.

8. The multilayered fabric of claim 7, where the staple is crimped.

9. The multilayered fabric of claim 3, where the first absorbable nonwoven fabric comprises staple having a length from about 1.5 to 2 inches.

10. The multilayered fabric of claim 9, where the staple is crimped.

11. The multilayered fabric of claim 9, where the staple is derived from fiber of about 1 to 4 denier per filament.

12. The multilayered fabric of claim 11, where the first absorbable nonwoven fabric has a basis weight of about 0.01 to 0.2 g/in²;

and the second absorbable woven or knitted fabric has a basis weight of about 0.001 to 0.2 g/in².

13. The multilayered fabric of claim 1, wherein the first absorbable nonwoven fabric comprises glycolide/lactide copolymer, and the second absorbable woven or knitted fabric comprises oxidized regenerated cellulose.

14. The multilayered fabric of claim 13, wherein the glycolide/lactide copolymer comprises from about 70 to 95 mole % glycolide and the remainder lactide.

15. The multilayered fabric of claim 1, wherein there is no more than a 10% variation in a basis weight of the fabric across each square inch.

16. A multilayered fabric comprising a first absorbable nonwoven fabric and a second absorbable woven or knitted fabric comprising oxidized polysaccharides, where the first absorbable nonwoven fabric comprises fibers comprised of aliphatic polyester polymers or copolymers of one or more monomers selected from the group consisting of lactic acid, lactide (including L-, D-, meso and D, L mixtures), glycolic acid and glycolide.

17. The multilayered fabric of claim 16, where the first absorbable nonwoven fabric comprises glycolide/lactide copolymer.

18. The multilayered fabric of claim 16, where the second absorbable woven or knitted fabric comprises oxidized cellulose.

19. The multilayered fabric of claim 18, where the second absorbable woven or knitted fabric comprises oxidized regenerated cellulose.

20. The multilayered fabric of claim 19, where the second absorbable woven or knitted fabric is an absorbable knitted fabric comprising oxidized regenerated cellulose.

21. The multilayered fabric of claim 18, where the first absorbable nonwoven fabric comprises staple having a length from about 0.75 to 2.5 inches.

22. The multilayered fabric of claim 21, where the staple is crimped.

23. The multilayered fabric of claim 18, where the first absorbable nonwoven fabric comprises staple having a length from about 1.5 to 2 inches.

24. The multilayered fabric of claim 23, where the staple is crimped.

25. The multilayered fabric of claim 23, where the staple is derived from fiber of about 1 to 4 denier per filament.

26. The multilayered fabric of claim 25, where the first absorbable nonwoven fabric has a basis weight of about 0.01 to 0.2 g/in²;

and the second absorbable woven or knitted fabric has a basis weight of about 0.001 to 0.2 g/in².

27. The multilayered fabric of claim 16, wherein the first absorbable nonwoven fabric comprises glycolide/lactide copolymer, and the second absorbable woven or knitted fabric comprises oxidized regenerated cellulose.

28. The multilayered fabric of claim 27, wherein the glycolide/lactide copolymer comprises from about 70 to 95 mole% glycolide and the remainder lactide.

29. The multilayered fabric of claim 16, wherein there is no more than a 10% variation in a basis weight of the fabric across each square inch.