Occlusion device

• US 7,670,373 B1
• Filed: 03/03/1998
• Issued: 03/02/2010
• Est. Priority Date: 04/30/1997
• Status: Expired due to Term

• Current Assignee: Pulmonx Corp.
• Original Assignee: Pulmonx Corp.
• Inventors: Sabanathan, legal representative, Sabanathan, Sabaratnam
• Primary Examiner(s): Yu; Justine R
• Assistant Examiner(s): MATTER, KRISTEN CLARETTE
• Application Number:
  US09/762,692
• Time in Patent Office: 4,382 Days
• Field of Search: 128/207.15, 606/157, 606/158, 623/2.26, 623/2.27, 623/2.34, 623/9, 623/11.11, 424/422, 424/423, 424/434, 424/489
• US Class Current: 623/9
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12104 in an air passage
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61F 2002/043 Bronchi

Abstract

An obturator for a bronchial tube or tubule of a human or animal lung comprises a blocking element (92) and a securing element (90). The blocking element serves to seal the tube or tubule against the passage of fluid past the obturator when the obturator is disposed in a bronchial tube or tubule. The securing element serves to retain the blocking element in position. The blocking element comprises a substantially cylindrical plug of biocompatible, resiliently deformable closed-cell foamed plastics material, such as PVC. The securing element comprises a stent having barbs (98) to engage and retain the blocking element. The stent also has anchors (100) to retain the stent in a bronchial tube or tubule. A method of treatment of emphysema or other lung conditions or diseases in human or animal patients comprises placing an obturator in a bronchial tube or tubule of the patient so as to seal the tube or tubule against the passage of fluid past the obturator.

Claims

1. A method of treating an individual having an abnormal permanent enlargement of an airspace distal to a bronchial tube in a lung, said method comprising:

providing a blocking element;

inserting a delivery tube through airways of the individual to the bronchial tube of the individual, wherein the delivery tube is loaded with the blocking element;

guiding the delivery tube to a suitable location within the bronchial tube; and

releasing the blocking element in the bronchial tube, wherein the blocking element prohibits air from flowing through the bronchial tube into the airspace as the patient inhales and isolates the airspace supplied by the bronchial tube so that the airspace deflates over time as the air in the airspace becomes absorbed.

2. The method of claim 1, wherein the blocking element is inserted in the bronchial tube in a compressed state and expands into engagement with a wall of the bronchial tube.

3. The method of claim 2, wherein the blocking element expands into sealing engagement with the bronchial tube to form an air tight seal between the blocking element and a wall of the bronchial tube.

4. The method of claim 1, wherein the blocking element comprises a securing element that is expandable to a shape suitable for engaging a wall of the bronchial tube.

5. The method of claim 4, wherein the blocking element is inserted in the bronchial tube in a compressed state and expands into engagement with the wall of the bronchial tube.

6. The method of claim 4, wherein the securing element comprises a stent.

7. A method as in claim 6, wherein the stent is a self-expanding stent.

8. The method of claim 4, wherein the securing element comprises a memory metal which is released to an expanded shape by a change in a physical parameter after it has been inserted in the terminal bronchiole.

9. The method of claim 1, wherein the blocking element comprises a substantially cylindrical plug of biocompatible material.

10. The method of claim 9, wherein the plug comprises resiliently deformable closed-cell foamed plastics material.

11. The method of claim 1, wherein the blocking element comprises a balloon or a diaphragm.

12. The method of claim 1, wherein the blocking element is released by pushing the blocking element out of the delivery tube.

13. The method of claim 1, further comprising:

providing a second blocking element;

inserting the second blocking element in a second bronchial tube of the individual; and

releasing the second blocking element in the second bronchial tube so that the second blocking element prohibits air from flowing through the second bronchial tube into a second airspace as the patient inhales and isolates the second airspace so that the second airspace deflates over time as the air in the second airspace becomes absorbed.

14. The method of claim 1, wherein the lung disease is emphysema.

15. A method of treating an individual having an abnormal permanent enlargement of an airspace distal to a bronchial tube in a lung, said method comprising:

guiding a delivery tube to a suitable location within the bronchial tube of the individual;

inserting a material from the delivery tube to the location in the bronchial tube so that the material prohibits air from flowing through the bronchial tube in both an inhalation direction and an exhalation direction; and

releasing the material in the from the delivery tube in the bronchial tube so that air is trapped in the airspace distal to the terminal bronchiole and is absorbed over time.

16. A method as in claim 15, wherein the abnormal permanently enlarged airspace is caused by emphysema.