System and method for characterizing patient respiration

• US 7,678,061 B2
• Filed: 04/15/2004
• Issued: 03/16/2010
• Est. Priority Date: 09/18/2003
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Stahmann, Jeffrey E., Hartley, Jesse W., Hatlestad, John D., Lee, Kent, Ni, Quan
• Primary Examiner(s): Mallari; Patricia C
• Application Number:
  US10/824,941
• Publication Number:
  US 20050065447A1
• Time in Patent Office: 2,161 Days
• Field of Search: 600/484, 600/534, 600/536, 600/529, 600/513
• US Class Current: 600/529
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/082 Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath A61B5/083, A61B5/091 take precedence
• CPC Class Codes: A61B 5/4806 Sleep evaluation A61B5/4821 takes precedence; devices for inducing sleep A61M21/02

Abstract

Patient respiration may be characterized using a marked respiration waveform involving a respiration waveform annotated with symbols, markers or other indicators representing one or more respiration characteristics. A respiration waveform may be acquired by sensing a physiological parameter modulated by respiration. A marked respiration waveform may be generated based on the acquired respiration waveform and one or more detected respiration waveform characteristics and/or respiration-related conditions. One or more components used to generate the marked respiratory waveform may be fully or partially implantable.

Claims

1. A system for characterizing respiration of a patient, comprising:

a respiration waveform sensor configured to acquire a respiration waveform;

a respiration processor configured to determine one or more characteristics associated with the respiration and comprising a trigger circuit configured to detect a triggering event, the one or more characteristics including a first respiration characteristic and a second respiration characteristic different from the first respiration characteristic; and

a waveform generator coupled to the respiration waveform sensor and the respiration processor, the waveform generator configured to generate a marked respiration waveform comprising the respiration waveform and symbols indicating the one or more characteristics associated with the respiration, the generation of the marked respiration waveform being activated in response to the detection of the triggering event, and the symbols including a first symbol indicating the first respiration characteristic and a second symbol indicating the second respiration characteristic, the first and second symbols being aligned relative to the respiration waveform to indicate times of occurrence of the first and second respiration characteristics respectively;

wherein at least one of the respiration waveform sensor, the respiration processor, and the waveform generator comprises an implantable component; and

wherein the respiration processor is further configured to distinguish between different types of disordered breathing, and the first respiration characteristic comprises a type of disordered breathing selected from the different types of disordered breathing.

2. The system of claim 1, wherein the type of the disordered breathing comprises central disordered breathing.

3. The system of claim 1, wherein the type of the disordered breathing comprises obstructive disordered breathing.

4. The system of claim 1, wherein the type of the disordered breathing comprises mixed central and obstructive disordered breathing.

5. The system of claim 1, wherein the type of the disordered breathing comprises apnea.

6. The system of claim 1, wherein the type of the disordered breathing comprises hypopnea.

7. The system of claim 1, wherein the type of the disordered breathing comprises mixed apnea and hypopnea.

8. The system of claim 1, wherein the type of the disordered breathing comprises Cheyne-Stokes respiration.

9. The system of claim 1, wherein the type of the disordered breathing comprises periodic breathing.

10. The system of claim 1, wherein the type of the disordered breathing comprises sleep disordered breathing.

11. A system for characterizing respiration of a patient, comprising:

a respiration waveform sensor configured to acquire a respiration waveform;

a respiration processor configured to determine one or more characteristics associated with the respiration and comprising a trigger circuit configured to detect a triggering event, the one or more characteristics including a first respiration characteristic and a second respiration characteristic different from the first respiration characteristic; and

a waveform generator coupled to the respiration waveform sensor and the respiration processor, the waveform generator configured to generate a marked respiration waveform comprising the respiration waveform and symbols indicating the one or more characteristics associated with the respiration, the generation of the marked respiration waveform being activated in response to the detection of the triggering event, and the symbols including a first symbol indicating the first respiration characteristic and a second symbol indicating the second respiration characteristic, the first and second symbols being aligned relative to the respiration waveform to indicate times of occurrence of the first and second respiration characteristics respectively;

wherein at least one of the respiration waveform sensor, the respiration processor, and the waveform generator comprises an implantable component; and

wherein the one or more characteristics associated with the respiration comprises a respiration volume.

12. A system for characterizing respiration of a patient, comprising:

a respiration waveform sensor configured to acquire a respiration waveform;

a respiration processor configured to determine one or more characteristics associated with the respiration and comprising a trigger circuit configured to detect a triggering event, the one or more characteristics including a first respiration characteristic and a second respiration characteristic different from the first respiration characteristic; and

a waveform generator coupled to the respiration waveform sensor and the respiration processor, the waveform generator configured to generate a marked respiration waveform comprising the respiration waveform and symbols indicating the one or more characteristics associated with the respiration, the generation of the marked respiration waveform being activated in response to the detection of the triggering event, and the symbols including a first symbol indicating the first respiration characteristic and a second symbol indicating the second respiration characteristic, the first and second symbols being aligned relative to the respiration waveform to indicate times of occurrence of the first and second respiration characteristics respectively;

wherein at least one of the respiration waveform sensor, the respiration processor, and the waveform generator comprises an implantable component; and

wherein the one or more characteristics associated with the respiration comprises minute ventilation.

13. A system for characterizing respiration of a patient, comprising:

a respiration waveform sensor configured to acquire a respiration waveform;

a respiration processor configured to determine one or more characteristics associated with the respiration and comprising a trigger circuit configured to detect a triggering event, the one or more characteristics including a first respiration characteristic and a second respiration characteristic different from the first respiration characteristic; and

a waveform generator coupled to the respiration waveform sensor and the respiration processor, the waveform generator configured to generate a marked respiration waveform comprising the respiration waveform and symbols indicating the one or more characteristics associated with the respiration, the generation of the marked respiration waveform being activated in response to the detection of the triggering event, and the symbols including a first symbol indicating the first respiration characteristic and a second symbol indicating the second respiration characteristic, the first and second symbols being aligned relative to the respiration waveform to indicate times of occurrence of the first and second respiration characteristics respectively;

wherein at least one of the respiration waveform sensor, the respiration processor, and the waveform generator comprises an implantable component; and

wherein the one or more characteristics associated with the respiration comprises expiration slope.

14. A system for characterizing respiration of a patient, comprising:

a respiration waveform sensor configured to acquire a respiration waveform;

a respiration processor configured to determine one or more characteristics associated with the respiration and comprising a trigger circuit configured to detect a triggering event, the one or more characteristics including a first respiration characteristic and a second respiration characteristic different from the first respiration characteristic; and

a waveform generator coupled to the respiration waveform sensor and the respiration processor, the waveform generator configured to generate a marked respiration waveform comprising the respiration waveform and symbols indicating the one or more characteristics associated with the respiration, the generation of the marked respiration waveform being activated in response to the detection of the triggering event, and the symbols including a first symbol indicating the first respiration characteristic and a second symbol indicating the second respiration characteristic, the first and second symbols being aligned relative to the respiration waveform to indicate times of occurrence of the first and second respiration characteristics respectively;

wherein at least one of the respiration waveform sensor, the respiration processor, and the waveform generator comprises an implantable component; and

wherein the one or more characteristics associated with the respiration comprises expiration volume.

15. A system for characterizing respiration of a patient, comprising:

a respiration waveform sensor configured to acquire a respiration waveform;

a respiration processor configured to determine one or more characteristics associated with the respiration and comprising a trigger circuit configured to detect a triggering event, the one or more characteristics including a first respiration characteristic and a second respiration characteristic different from the first respiration characteristic; and

a waveform generator coupled to the respiration waveform sensor and the respiration processor, the waveform generator configured to generate a marked respiration waveform comprising the respiration waveform and symbols indicating the one or more characteristics associated with the respiration, the generation of the marked respiration waveform being activated in response to the detection of the triggering event, and the symbols including a first symbol indicating the first respiration characteristic and a second symbol indicating the second respiration characteristic, the first and second symbols being aligned relative to the respiration waveform to indicate times of occurrence of the first and second respiration characteristics respectively;

wherein at least one of the respiration waveform sensor, the respiration processor, and the waveform generator comprises an implantable component; and

wherein the respiration processor is configured to detect the one or more characteristics associated with the respiration based on morphological features of the respiratory waveform.