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Selection and use of lactic acid bacteria for reducing inflammation caused by Helicobacter

  • US 7,678,553 B2
  • Filed: 12/03/2008
  • Issued: 03/16/2010
  • Est. Priority Date: 10/07/2002
  • Status: Expired due to Fees
First Claim
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1. A method for selecting a lactic acid bacterial strain for administration to a mammal for reducing gastrointestinal inflammation associated with Helicobacter pylori infection in the gastrointestinal tract of said mammal, comprising the steps of:

  • a) selecting and culturing a Lactobacillus strain;

    b) obtaining a cell-free culture supernatant from said strain; and

    c) evaluating the level of TNFα

    in the supernatant using a model system.

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