High alcohol content gel-like and foaming compositions comprising an anionic phosphate fluorosurfactant

• US 7,683,018 B2
• Filed: 08/22/2006
• Issued: 03/23/2010
• Est. Priority Date: 09/29/2003
• Status: Active Grant

• Current Assignee: DEB IP Limited (SC Johnson & Son Incorporated)
• Original Assignee: DEB Worldwide Healthcare Incorporated
• Inventors: Fernandez de Castro, Maria Teresa, Koivisto, Bruce Michael
• Primary Examiner(s): Boyer; Charles I
• Application Number:
  US11/507,626
• Publication Number:
  US 20070027055A1
• Time in Patent Office: 1,309 Days
• Field of Search: 510/130, 510/149, 510/157, 510/432, 510/436, 510/138
• US Class Current: 510/138
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/04 Dispersions, emulsions, suspoemulsions, suspension concentrates or gels foams A01N25/16
• CPC Class Codes: A01N 25/16 Foams
• CPC Class Codes: A01N 25/30 characterised by the surfactants
• CPC Class Codes: A01N 31/02 Acyclic compounds
• CPC Class Codes: A01N 33/12 Quaternary ammonium compounds
• CPC Class Codes: A01N 47/44 Guanidine; Derivatives thereof
• CPC Class Codes: A61K 31/045 Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
• CPC Class Codes: A61K 31/08 acyclic, e.g. paraformaldehyde
• CPC Class Codes: A61K 31/195 having an amino group
• CPC Class Codes: A61K 31/661 Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61K 8/046 Aerosols; Foams
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/8123 Compositions of homopolymers or copolymers of compounds having one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers, e.g. PVC, PTFE
• CPC Class Codes: A61K 8/86 Polyethers
• CPC Class Codes: A61L 2/235 cellular, porous or foamed
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 31/02 Local antiseptics
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 19/00 : Preparations for care of the skin
• CPC Class Codes: C11D 1/004 : Surface-active compounds containing F
• CPC Class Codes: C11D 1/006 : Surface-active compounds containing fluorine and phosphorus
• CPC Class Codes: C11D 17/003 : Colloidal solutions, e.g. gels; Thixotropic solutions or pastes
• CPC Class Codes: C11D 17/0043 : For use with aerosol devices
• CPC Class Codes: C11D 3/0094 : High foaming compositions
• CPC Class Codes: C11D 3/201 : linear
• CPC Class Codes: C11D 3/2013 : fatty or with at least 8 carbon atoms in the alkyl chain

Abstract

This invention relates to a “high lower alcohol content” (>40% v/v of a C_1-4 alcohol) liquid composition able to be either dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers or as an alcohol gel composition which does not use thickener and gelling agents that leave undesirable deposits or a sticky after-feel and that has a final viscosity less than 4,000 cps. The liquid compositions comprise an alcohol, C_1-4 (>40% v/v), a fluorosurfactant of at least 0.001% by weight to prepare a foamable composition or from 0-2.0% to prepare a gel-like composition of a final viscosity less than 4,000 cps, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition or a gel-like composition with a viscosity less than 4,000 cps), and the balance being purified water. The compositions may include emulsifier-emollients and moisturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.

Claims

1. A method of forming a skin disinfecting foam containing alcohol, comprising the steps of:

activating a dispenser pump of an unpressurized dispenser to combine an alcohol-fluorosurfactant mixture with air to form and dispense a skin disinfecting foam containing alcohol, wherein the alcohol-fluorosurfactant mixture comprises an alcohol C_1-4, or mixtures thereof, present in an amount greater than or equal to 60% by weight of the total composition, a physiologically acceptable effective anionic phosphate fluorosurfactant for foaming present in an amount of at least 0.001% by weight percent of the total composition, and water present in an amount to balance the total composition to 100% by weight.

2. The method of claim 1 wherein the effective physiologically acceptable anionic phosphate fluorosurfactant is for wetting.

3. The method according to claim 1 wherein the anionic phosphate fluorosurfactant is present in an amount from about 0.001% to about 10.0% by weight of the total composition.

4. The method according to claim 1 wherein the alcohol C_1-4 is an aliphatic alcohol selected from the group consisting of methanol, ethanol, isopropanol, n-propanol, butanol and combinations thereof.

5. The method according to claim 3 wherein the anionic phosphate fluorosurfactant has the following structure:

(RfCH₂CH₂O)_xP(O)(ONH₄)_y, where Rf═

F(CF₂CF₂)_z, x=1 or 2, y=2 or 1, x+y=3, and z=1 to about 7 or mixtures thereof.

6. The method according to claim 1 wherein the alcohol is present in a range from 60% to about 90% by weight.

7. The method according to claim 1 further including at least one additional surfactant for adjusting properties of the foam produced from the composition.

8. The method according to claim 7 wherein the additional surfactant is selected from the group consisting of a poly(ethoxylated and/or propoxylated)alcohol, a poly(ethoxylated and/or propoxylated)ester, a derivative of a poly(ethoxylated and/or propoxylated)alcohol, a derivative of a poly(ethoxylated and/or propoxylated)ester, an alkyl alcohol, an alkenyl alcohol, an ester of a polyhydric alcohol, an ether of a polyhydric alcohol, an ester of a polyalkoxylated derivative of a polyhydric alcohol, an ether of a polyalkoxylated derivative of a polyhydric alcohol, a sorbitan fatty acid ester, a polyalkoxylated derivative of a sorbitan fatty acid ester, an alkylglucoside, a betaine, a sulfobetaine, an imidazoline derivative, an aminoacid derivative, a lecithin, a phosphatide, an amine oxide, a sulfoxide and mixtures thereof, present in an amount between about 0.10% to about 5% by weight.

11. The method according to claim 1, wherein the anionic phosphate fluorosurfactant is of the structure:

(RfCH₂CH₂O)_xP(O)(O⁻

)_y, where Rf═

F(CF₂CF₂)_z, x=1 or 2, y=2 or 1, x+y=3, and z=1 to about 7.

12. The method according to claim 1, wherein the composition does not include a propellant.

9. A method for personal disinfecting comprising:

applying to a person'"'"'s skin a skin-disinfecting alcohol foam composition which comprises

a) air mixed under low pressure conditions with

b) a liquid comprising

i) an alcohol C_1-4, or mixtures thereof, present in an amount greater than or equal to 60% by weight of the total composition;

ii) water present in an amount to balance the total composition to 100% by weight; and

iii) a physiologically acceptable anionic phosphate fluorosurfactant for foaming present in an amount of at least 0.001% by weight of the total composition.

13. The method according to claim 9 wherein the anionic phosphate fluorosurfactant is for wetting.

14. The method according to claim 9 wherein the effective anionic phosphate fluorosurfactant is present in an amount from about 0.001% to about 10.0% by weight of the total composition.

15. The method according to claim 9 wherein the alcohol C_1-4 is an aliphatic alcohol selected from the group consisting of methanol, ethanol, isopropanol, n-propanol, butanol and combinations thereof.

16. The method according to claim 9 wherein the anionic phosphate fluorosurfactant has the following structure:

(RfCH₂CH₂O)_xP(O)(ONH₄)_y, where Rf═

F(CF₂CF₂)z, x=1 or 2, y=2 or 1, x+y=3, and z=1 to about 7 or mixtures thereof.

17. The method according to claim 9 wherein the alcohol is present in a range from 60% to 90% by weight.

18. The method according to claim 9 wherein the alcohol is ethanol present in an amount of at least 60% by weight.

19. The method according to claim 9 wherein the alcohol is a mixture of n-propanol and ethanol present in a combined amount of at least 60% by weight.

20. The method according to claim 9 wherein the alcohol is a mixture of isopropanol and ethanol present in a combined amount of at least 60% by weight.

21. The method according to claim 9 wherein the alcohol is isopropanol present in an amount of at least 70% v/v.

22. The method according to claim 9 wherein the alcohol is n-propanol present in an amount of at least 60% by weight.

23. The method according to claim 9 wherein the alcohol foam composition further includes at least one additional surfactant for adjusting properties of the composition and/or the resulting foam produced from the composition.

24. The method according to claim 23 wherein the additional surfactant is selected from the group consisting of a poly(ethoxylated and/or propoxylated)alcohol, a poly(ethoxylated and/or propoxylated)ester, a derivative of a poly(ethoxylated and/or propoxylated)alcohol, a derivative of a poly(ethoxylated and/or propoxylated)ester, an alkyl alcohol, an alkenyl alcohol, an ester of a polyhydric alcohol, an ether of a polyhydric alcohol, an ester of a polyalkoxylated derivative of a polyhydric alcohol, an ether of a polyalkoxylated derivative of a polyhydric alcohol, a sorbitan fatty acid ester, a polyalkoxylated derivative of a sorbitan fatty acid ester, an alkylglucoside, a betaine, a sulfobetaine, an imidazoline derivative, an aminoacid derivative, a lecithin, a phosphatide, an amine oxide, a sulfoxide and mixtures thereof, present in an amount between about 0.10% to about 5% by weight.

25. The method according to claim 24 wherein the betaine is cocamidopropyl betaine.

26. The method according to claim 24 wherein the alkylglucoside is cocoglucoside.

27. The method according to claim 24 wherein the polyethoxylated fatty alcohol is polyethoxylated stearyl alcohol (21 moles ethylene oxide).

28. The method according to claim 24 wherein the polyethoxylated fatty alcohol is polyethoxylated stearyl alcohol (2 moles ethylene oxide).

29. The method according to claim 24 wherein the polyethoxylated fatty alcohol is a combination of polyethoxylated stearyl alcohol (21 moles ethylene oxide) and polyethoxylated stearyl alcohol (2 moles ethylene oxide).

30. The method according to claim 9 wherein the alcohol foam composition includes a foam stabilizing agent present in an amount up to 5% by weight.

31. The method according to claim 30 wherein the foam stabilizing agent is selected from the group consisting of lactic acid esters of monoglycerides, cationic emulsifiers, triquaternized stearic phospholipid complex, hydroxystearamide propyltriamine salts, lactic acid monoglycerides, food emulsifiers selected from the group consisting of glyceryl monostearate, propylene glycol monostearate, sodium stearoyl lactylate, cetyl betaine, glycolether, n-propanol, butyleneglycol, silicone wax, an encapsulated oil, Microcapsule Mineral Oil®

, and combinations thereof.

32. The method according to claim 30 wherein the foam stabilizing agent is selected from the group consisting of glycolether, n-propanol, butyleneglycol, and combinations thereof.

33. The method according to claim 9 wherein the alcohol foam composition includes any one of a moisturizer, emollient and combinations thereof selected from the group consisting of

lanolin,

vinyl alcohol,

polyvinyl pyrrolidone,

polyols selected from the group consisting of glycerol, propylene glycol, butyleneglycol and sorbitol,

a fatty alcohol selected from the group consisting of cetyl alcohol, stearyl alcohol, lauryl alcohol, myristyl alcohol and palmityl alcohol,

ceteareth 20,

an alkylglucoside

and combinations thereof, present in an amount up to 5% by weight.

34. The method according to claim 9 wherein the alcohol foam composition further comprises an acid or a base to adjust a pH of the composition to a pre-selected pH present in an amount from about 0.05 to about 0.5% by weight of the total composition.

35. The method according to claim 34 wherein the acid is selected from the group consisting of hydrochloric acid, citric acid and phosphoric acid when an acid is used to adjust the pH, and wherein the base is sodium sesquicarbonate when a base is used to adjust the pH.

36. The method according to claim 9 wherein the alcohol foam composition includes a preservative in an amount from about 0.01 to about 5% by weight of the total composition.

37. The method according to claim 9 wherein the alcohol foam composition includes an antimicrobial agent.

38. The method according to claim 37 wherein the antimicrobial agent is chlorhexidine gluconate present in an amount between about 0.50% to about 4.0% by weight.

39. The method according to claim 37 wherein the antimicrobial agent is didecyl dimethyl ammonium chloride present in an amount between about 0.05% to about 5.0% by weight.

40. The method according to claim 37 wherein the antimicrobial agent is selected from the group consisting of a chlorhexidine salt, iodine, a complexed form of iodine, parachlorometaxylenol, triclosan, hexachlorophene, a phenol, a surfactant having a long chain hydrophobic group and a quaternary group, hydrogen peroxide, silver, a silver salt, silver oxide, and mixtures thereof.

41. The method according to claim 9 wherein the alcohol foam composition further comprises constituents selected from the group consisting of organic gums and colloids, lower alkanolamides of higher fatty acids, short chain diols and/or triols, fragrance, coloring matter, ultraviolet absorbers, solvents, suspending agents, buffers, conditioning agents, antioxidants, bactericides and medicinally active ingredients, and combinations thereof.

42. The method according to claim 9, wherein the alcohol C_1-4 or mixtures thereof is ethanol present in an amount between 60% to about 70% by weight of the total composition, and the anionic phosphate fluorosurfactant is present in an amount from about 0.01% to about 2.0% by weight of the total composition.

43. The method according to claim 42 wherein the alcohol foam composition further comprises at least one secondary surfactant present in an amount from about 0.01 to about 10.0% by weight of the total composition, wherein the secondary surfactant is at least one selected from the group consisting of a poly(ethoxylated and/or propoxylated)alcohol, a poly(ethoxylated and/or propoxylated)ester, a derivative of a poly(ethoxylated and/or propoxylated)alcohol, a derivative of a poly(ethoxylated and/or propoxylated)ester, an alkyl alcohol, an alkenyl alcohol, an ester of a polyhydric alcohol, an ether of a polyhydric alcohol, an ester of a polyalkoxylated derivative of a polyhydric alcohol, an ether of a polyalkoxylated derivative of a polyhydric alcohol, a sorbitan fatty acid ester, a polyalkoxylated derivative of a sorbitan fatty acid ester, a betaine, a sulfobetaine, an imidazoline derivative, an aminoacid derivative, a lecithin, a phosphatide, an amine oxide, a sulfoxide and mixtures thereof, present in an amount between about 0.10% to about 5% by weight.

44. The method according to claim 42 wherein the alcohol foam composition includes an emulsifier or mixture of emulsifiers present in an amount between about 0.10% to about 1.5% by weight.

45. The method according to claim 44 wherein the emulsifier is a mixture of cetyl ethers and stearyl ethers of polyethylene oxide having an average of about 20 oxide units.

46. The method according to claim 42 wherein the alcohol foam composition further comprises a foam stabilizing agent, wherein the foam stabilizing agent is cetyl betaine.

47. The method according to claim 9 wherein the alcohol is ethanol present in an amount between 60% to about 70% by weight of the total composition, and the anionic phosphate fluorosurfactant is present in an amount from about 0.001% to about 5.0% by weight of the total composition.

48. The method according to claim 47 wherein the alcohol foam composition includes a foam stabilizing agent.

49. The method according to claim 48 wherein said foam stabilizing agent is selected from the group consisting of 1,3-Butyleneglycol, Butoxyethanol and combinations thereof.

50. The method according to claim 49 wherein said foam stabilizing agent is present in a range from about 0.001 to about 3% by weight.

51. The method according to claim 47 wherein the alcohol foam composition includes a lipid layer enhancer.

52. The method according to claim 51 wherein said lipid layer enhancer is selected from the group consisting of alkylglucoside, glyceryl oleate and combinations thereof.

53. The method according to claim 47 wherein the alcohol foam composition includes n-propanol present in an amount of at least about 1% v/v.

54. The method according to claim 47 wherein said anionic phosphate fluorosurfactant for foaming is present in an amount from about 0.001% to about 2.0% by weight.

56. The method according to claim 9, wherein the composition does not include a propellant.

10. A method for producing, and applying to a person'"'"'s skin, a skin-disinfecting alcohol foam composition, comprising

activating a dispenser pump of an unpressurized dispenser to combine an alcohol-fluorosurfactant mixture with air to form and dispense a skin-disinfecting alcohol foam, the alcohol-fluorosurfactant mixture comprising an alcohol C_1-4, or mixtures thereof, present in an amount greater than or equal to 60% by weight of the total composition, a physiologically acceptable anionic phosphate fluorosurfactant for foaming, present in an amount of at least 0.001% by weight of the total composition, and water present in an amount to balance the total composition to 100% by weight;

and

applying the skin-disinfecting alcohol foam to the person'"'"'s skin.

57. The method according to claim 10 wherein the anionic phosphate fluorosurfactant is for wetting.

58. The method according to claim 10 wherein the anionic phosphate fluorosurfactant is present in an amount from about 0.001% to about 10.0% by weight of the total composition.

59. The method according to claim 10 wherein the alcohol C_1-4 is an aliphatic alcohol selected from the group consisting of methanol, ethanol, isopropanol, n-propanol, butanol and combinations thereof.

60. The method according to claim 10 wherein the anionic phosphate fluorosurfactant has the following structure:

(RfCH₂CH₂O)_xP(O)(ONH₄)_y, where Rf═

F(CF₂CF₂)z, x=1 or 2, y=2 or 1, x+y=3, and z=1 to about 7 or mixtures thereof.

61. The method according to claim 10 wherein the alcohol is present in a range from 60% to 90% by weight.

62. The method according to claim 10 wherein the alcohol is ethanol present in an amount of at least 60% by weight.

63. The method according to claim 10 wherein the alcohol is a mixture of n-propanol and ethanol present in a combined amount of at least 60% by weight.

64. The method according to claim 10 wherein the alcohol is a mixture of isopropanol and ethanol present in a combined amount of at least 60% by weight.

65. The method according to claim 10 wherein the alcohol is isopropanol present in an amount of at least 70% v/v.

66. The method according to claim 10 wherein the alcohol is n-propanol present in an amount of at least 60% by weight.

67. The method according to claim 10 wherein the alcohol foam composition further includes at least one additional surfactant for adjusting properties of the composition and/or the resulting foam produced from the composition.

68. The method according to claim 67 wherein the additional surfactant is selected from the group consisting of a poly(ethoxylated and/or propoxylated)alcohol, a poly(ethoxylated and/or propoxylated)ester, a derivative of a poly(ethoxylated and/or propoxylated)alcohol, a derivative of a poly(ethoxylated and/or propoxylated)ester, an alkyl alcohol, an alkenyl alcohol, an ester of a polyhydric alcohol, an ether of a polyhydric alcohol, an ester of a polyalkoxylated derivative of a polyhydric alcohol, an ether of a polyalkoxylated derivative of a polyhydric alcohol, a sorbitan fatty acid ester, a polyalkoxylated derivative of a sorbitan fatty acid ester, an alkylglucoside, a betaine, a sulfobetaine, an imidazoline derivative, an aminoacid derivative, a lecithin, a phosphatide, an amine oxide, a sulfoxide and mixtures thereof, present in an amount between about 0.10% to about 5% by weight.

69. The method according to claim 68 wherein the betaine is cocamidopropyl betaine.

70. The method according to claim 68 wherein the alkylglucoside is cocoglucoside.

71. The method according to claim 68 wherein the polyethoxylated fatty alcohol is polyethoxylated stearyl alcohol (21 moles ethylene oxide).

72. The method according to claim 68 wherein the polyethoxylated fatty alcohol is polyethoxylated stearyl alcohol (2 moles ethylene oxide).

73. The method according to claim 68 wherein the polyethoxylated fatty alcohol is a combination of polyethoxylated stearyl alcohol (21 moles ethylene oxide) and polyethoxylated stearyl alcohol (2 moles ethylene oxide).

74. The method according to claim 10 wherein the alcohol foam composition includes a foam stabilizing agent present in an amount up to 5% by weight.

75. The method according to claim 74 wherein the foam stabilizing agent is selected from the group consisting of lactic acid esters of monoglycerides, cationic emulsifiers, triquaternized stearic phospholipid complex, hydroxystearamide propyltriamine salts, lactic acid monoglycerides, food emulsifiers selected from the group consisting of glyceryl monostearate, propylene glycol monostearate, sodium stearoyl lactylate, cetyl betaine, glycolether, n-propanol, butyleneglycol, silicone wax, an encapsulated oil, Microcapsule Mineral Oil®

, and combinations thereof.

76. The method according to claim 74 wherein the foam stabilizing agent is selected from the group consisting of glycolether, n-propanol, butyleneglycol, and combinations thereof.

77. The method according to claim 10 wherein the alcohol foam composition includes any one of a moisturizer, emollient and combinations thereof selected from the group consisting of

lanolin,

vinyl alcohol,

polyvinyl pyrrolidone,

polyols selected from the group consisting of glycerol, propylene glycol, butyleneglycol and sorbitol,

a fatty alcohol selected from the group consisting of cetyl alcohol, stearyl alcohol, lauryl alcohol, myristyl alcohol and palmityl alcohol,

ceteareth 20,

an alkylglucoside

and combinations thereof, present in an amount up to 5% by weight.

78. The method according to claim 10 wherein the alcohol foam composition further comprises an acid or a base to adjust a pH of the composition to a pre-selected pH present in an amount from about 0.05 to about 0.5% by weight of the total composition.

79. The method according to claim 78 wherein the acid is selected from the group consisting of hydrochloric acid, citric acid and phosphoric acid when an acid is used to adjust the pH, and wherein the base is sodium sesquicarbonate when a base is used to adjust the pH.

80. The method according to claim 10 wherein the alcohol foam composition includes a preservative in an amount from about 0.01 to about 5% by weight of the total composition.

81. The method according to claim 10 wherein the alcohol foam composition includes an antimicrobial agent.

82. The method according to claim 81 wherein the antimicrobial agent is chlorhexidine gluconate present in an amount between about 0.50% to about 4.0% by weight.

83. The method according to claim 81 wherein the antimicrobial agent is didecyl dimethyl ammonium chloride present in an amount between about 0.05% to about 5.0% by weight.

84. The method according to claim 81 wherein the antimicrobial agent is selected from the group consisting of a chlorhexidine salt, iodine, a complexed form of iodine, parachlorometaxylenol, triclosan, hexachlorophene, a phenol, a surfactant having a long chain hydrophobic group and a quaternary group, hydrogen peroxide, silver, a silver salt, silver oxide, and mixtures thereof.

85. The method according to claim 10 wherein the alcohol foam composition further comprises constituents selected from the group consisting of organic gums and colloids, lower alkanolamides of higher fatty acids, short chain diols and/or triols, fragrance, coloring matter, ultraviolet absorbers, solvents, suspending agents, buffers, conditioning agents, antioxidants, bactericides and medicinally active ingredients, and combinations thereof.

86. The method according to claim 10, wherein the alcohol C_1-4 or mixtures thereof is ethanol present in an amount between 60% to about 70% by weight of the total composition, and the anionic phosphate fluorosurfactant is present in an amount from about 0.01% to about 2.0% by weight of the total composition.

87. The method according to claim 86 wherein the alcohol foam composition further comprises at least one secondary surfactant present in an amount from about 0.01 to about 10.0% by weight of the total composition, wherein the secondary surfactant is at least one selected from the group consisting of a poly(ethoxylated and/or propoxylated)alcohol, a poly(ethoxylated and/or propoxylated)ester, a derivative of a poly(ethoxylated and/or propoxylated)alcohol, a derivative of a poly(ethoxylated and/or propoxylated)ester, an alkyl alcohol, an alkenyl alcohol, an ester of a polyhydric alcohol, an ether of a polyhydric alcohol, an ester of a polyalkoxylated derivative of a polyhydric alcohol, an ether of a polyalkoxylated derivative of a polyhydric alcohol, a sorbitan fatty acid ester, a polyalkoxylated derivative of a sorbitan fatty acid ester, a betaine, a sulfobetaine, an imidazoline derivative, an aminoacid derivative, a lecithin, a phosphatide, an amine oxide, a sulfoxide and mixtures thereof, present in an amount between about 0.10% to about 5% by weight.

88. The method according to claim 86 wherein the alcohol foam composition includes an emulsifier or mixture of emulsifiers present in an amount between about 0.10% to about 1.5% by weight.

89. The method according to claim 88 wherein the emulsifier is a mixture of cetyl ethers and stearyl ethers of polyethylene oxide having an average of about 20 oxide units.

90. The method according to claim 86 wherein the alcohol foam composition further comprises a foam stabilizing agent, wherein the foam stabilizing agent is cetyl betaine.

91. The method according to claim 87 wherein the alcohol is ethanol present in an amount between 60% to about 70% by weight of the total composition, and the anionic phosphate fluorosurfactant is present in an amount from about 0.001% to about 5.0% by weight of the total composition.

92. The method according to claim 91 wherein the alcohol foam composition includes a foam stabilizing agent.

93. The method according to claim 92 wherein said foam stabilizing agent is selected from the group consisting of 1,3-Butyleneglycol, Butoxyethanol and combinations thereof.

94. The method according to claim 93 wherein said foam stabilizing agent is present in a range from about 0.001 to about 3% by weight.

95. The method according to claim 91 wherein the alcohol foam composition includes a lipid layer enhancer.

96. The method according to claim 95 wherein said lipid layer enhancer is selected from the group consisting of alkylglucoside, glyceryl oleate and combinations thereof.

97. The method according to claim 91 wherein the alcohol foam composition includes n-propanol present in an amount of at least about 1% v/v.

98. The method according to claim 91 wherein said physiologically acceptable anionic phosphate fluorosurfactant for foaming is present in an amount from about 0.001% to about 2.0% by weight.

100. The method according to claim 10, wherein the composition does not include a propellant.

101. The method according to claim 100, wherein the fluorinated surface active agent is an anionic fluorinated surface active agent.

55. A method for personal disinfecting comprising:

applying to a person'"'"'s skin a skin-disinfecting alcohol foam composition which comprises

a) air mixed under low pressure conditions with

b) a liquid comprising

i) an alcohol C_1-4, or mixtures thereof, present in an amount greater than or equal to 60% by weight of the total composition;

ii) water present in an amount to balance the total composition to 100% by weight; and

iii) a physiologically acceptable anionic phosphate fluorosurfactant for foaming present in an amount of at least 0.001% by weight of the total composition, wherein said effective anionic phosphate fluorosurfactant is of the structure;

(RfCH₂CH₂O)_xP(O)(O⁻

)_y, where Rf═

F(CF₂CF₂)_z, x=1 or 2, y=2 or 1, x+y=3, and z=1 to about 7.

102. The method according to claim 55 wherein the alcohol foam composition includes one or more moisturizers or emollients.

103. The method according to claim 55 wherein the alcohol foam composition further includes at least one additional surfactant.

104. The method according to claim 55 wherein the alcohol foam composition includes a foam stabilizing agent present in an amount up to 5% by weight.

99. A method for producing, and applying to a person'"'"'s skin, a skin-disinfecting alcohol foam composition, comprising

activating a dispenser pump of an unpressurized dispenser to combine an alcohol-fluorosurfactant mixture with air to form and dispense a skin-disinfecting alcohol foam, the alcohol-fluorosurfactant mixture comprising an alcohol C_1-4, or mixtures thereof, present in an amount greater than 60% by weight of the total composition, a physiologically acceptable anionic phosphate fluorosurfactant, present in an amount of at least 0.001% by weight of the total composition, and water present in an amount to balance the total composition to 100% by weight, wherein said anionic phosphate fluorosurfactant is of the structure:

(RfCH₂CH₂O)_xP(O)(O⁻

)_y, where Rf═

F(CF₂CF₂)_z, x=1 or 2, y=2 or 1, x+y=3, and z=1 to about 7, and

applying the skin-disinfecting alcohol foam to the person'"'"'s skin.

105. The method according to claim 99 wherein the alcohol foam composition further includes one or more moisturizers or emollients.

106. The method according to claim 99 wherein the alcohol foam composition further includes at least one additional surfactant.

107. The method according to claim 99 wherein the alcohol foam composition further includes a foam stabilizing agent present in an amount up to 5% by weight.