Method and apparatus for acquiring free-breathing MR images using navigator echo with saturation RF pulse

• US 7,689,263 B1
• Filed: 09/15/2005
• Issued: 03/30/2010
• Est. Priority Date: 09/15/2005
• Status: Active Grant

• Current Assignee: General Electric Company
• Original Assignee: General Electric Company
• Inventors: Fung, Maggie M., Foo, Thomas K. F.
• Primary Examiner(s): Winakur; Eric F
• Assistant Examiner(s): Laryea; Lawrence N
• Application Number:
  US11/162,589
• Time in Patent Office: 1,657 Days
• Field of Search: 600/420, 600/410, 600/419, 600/529, 600/411, 600/413, 600/407, 324/306, 324307-309
• US Class Current: 600/410
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: G01R 33/4828 Resolving the MR signals of different chemical species, e.g. water-fat imaging
• CPC Class Codes: G01R 33/5607 by reducing the NMR signal of a particular spin species, e.g. of a chemical species for fat suppression, or of a moving spin species for black-blood imaging
• CPC Class Codes: G01R 33/5613 Generating steady state signals, e.g. low flip angle sequences [FLASH]
• CPC Class Codes: G01R 33/56509 due to motion, displacement or flow, e.g. gradient moment nulling G01R33/567 takes precedence
• CPC Class Codes: G01R 33/5673 Gating or triggering based on a physiological signal other than an MR signal, e.g. ECG gating or motion monitoring using optical systems for monitoring the motion of a fiducial marker
• CPC Class Codes: G01R 33/5676 Gating or triggering based on an MR signal, e.g. involving one or more navigator echoes for motion monitoring and correction

Abstract

A system and method of free-breathing MR imaging saturates an entire navigator profile at the end of an imaging segment of physiological motion cycle, e.g., heart cycle, thereby providing a uniform recovery of longitudinal magnetization for the next imaging cycle. Through use of at least one dephaser gradient following the image acquisition segment and a navigator RF saturation pulse, residual transverse magnetization is dephased and spins within a navigator tracker are saturated to ensure a uniform recovery of longitudinal magnetization for the next imaging period.

Claims

1. An magnetic resonance (MR) imaging apparatus comprising:

a plurality of gradient coils positioned about a bore of a magnet to impress a polarizing magnetic field and an RF transceiver system and an RF switch controlled by a pulse module to transmit RF signals to an RF coil assembly to acquire MR images; and

a computer programmed to apply a pulse sequence during an imaging period of a free-breathing gated acquisition, the pulse sequence defined by;

a navigator RF excitation pulse designed to selectively excite a tracker column;

an image acquisition segment designed to acquire MR data from a region-of-interest; and

a navigator RF saturation pulse designed to saturate the tracker column such that longitudinal-magnetization recovery in the tracker column is uniform for a next imaging period.

2. The MR imaging apparatus of claim 1 wherein the pulse sequence is further defined by at least one dephaser gradient designed to dephase residual transverse magnetization in the tracker column that is played out after the image acquisition segment and before the navigator RF saturation pulse.

3. The MR imaging apparatus of claim 1 wherein a spatial coverage of the navigator RF saturation pulse has a diameter greater than that of the navigator RF excitation pulse.

4. The MR imaging apparatus of claim 3 wherein the diameter of the spatial coverage of the navigator RF saturation pulse is 1.5 times greater than that of the navigator RF excitation pulse.

5. The MR imaging apparatus of claim 1 wherein the navigator RF saturation pulse has a flip angle of ninety degrees.

6. The MR imaging apparatus of claim 1 wherein the computer is further programmed to repeat the pulse sequence during each imaging period of a physiologically gated acquisition until all desired views are acquired.

7. The MR imaging apparatus of claim 6 wherein each imaging period is defined by an R-R interval of a cardiac cycle.

8. The MR imaging apparatus of claim 1 wherein the pulse sequence is further defined by a fat saturation pulse designed to saturate spins from fat in the region-of-interest, the fat saturation pulse played out after the navigator RF excitation pulse and before the image acquisition segment.

9. The MR imaging apparatus of claim 1 wherein the computer is further programmed to sample an echo excited by the navigator RF excitation pulse during the image acquisition segment and determine respiratory motion in the tracker column from the sampled echo.

10. The MR imaging apparatus of claim 1 wherein the computer is further programmed to acquire 3D MR data during the image acquisition segment.

11. A method of MR imaging comprising the steps of:

(A) acquiring navigator echo data elicited by an RF navigator excitation pulse applied to a tracker portion of a subject to be imaged;

(B) applying an imaging sequence to acquire MR data from a region-of-interest;

(C) applying an RF saturation pulse to saturate spins within the tracker portion after acquisition of the MR data;

(D) repeating steps (A)-(C) in each cycle of a physiologically gated acquisition; and

(E) reconstructing an image based on the acquired MR data.

12. The method of claim 11 further comprising the steps of acquiring MR data from the region-of-interest during free-breathing of the subject.

13. The method of claim 11 further comprising the step of applying a fat saturation pulse after step (A).

14. The method of claim 11 further comprising the step of applying x,y,z dephaser gradients after step (B).

15. The method of claim 11 wherein the physiologically gated acquisition is either a cardiac or a respiratory gated acquisition.

16. The method of claim 11 wherein the RF saturation pulse has a flip angle of ninety degrees and a spatial coverage that is larger than that of the RF navigator excitation pulse.

17. The method of claim 11 further comprising the step of defining the tracker position to have a location where physiological motion of the subject can be captured.

18. The method of claim 11 wherein the region-of-interest includes an abdominal/cardiac region of the subject.

19. A computer readable storage medium having instructions stored thereon that when executed by a computer cause the computer to:

acquire navigator tracking data from a navigator excitation region;

acquire imaging data for a segment of k-space from a region-of-interest;

suppress residual longitudinal magnetization in the navigator excitation region;

repeat the acquisition of tracking data and imaging data and suppression of longitudinal magnetization every cycle of a gated acquisition until k-space is acquired; and

reconstruct an image based on the imaging data.

20. The computer readable storage medium of claim 19 wherein the computer is further caused to retrospectively gate acquisition of the imaging data based on the navigator tracking data such that imaging data acquired during intervals between physiological motion is used for image reconstruction.

21. The computer readable storage medium of claim 19 wherein the computer is further caused to acquire imaging data during subject free-breathing.

22. The computer readable storage medium of claim 19 wherein the computer is further caused to suppress signal from fat in the region-of-interest prior to the acquisition of imaging data.

23. The computer readable storage medium of claim 19 wherein the computer is further caused to apply dephaser gradients in x,y,z, directions following the acquisition of the imaging data.

24. The computer readable storage medium of claim 19 wherein the computer is further caused to apply a navigator saturation pulse with a ninety degree flip angle to suppress the residual longitudinal magnetization in the navigator excitation region.

25. The computer readable storage medium of claim 24 wherein spatial coverage of navigator saturation RF pulse has a diameter 1.5 times greater than that of a navigation excitation pulse applied to excite spins in the navigator excitation region.