Delivery of therapeutic devices

• US 7,691,124 B2
• Filed: 01/31/2006
• Issued: 04/06/2010
• Est. Priority Date: 01/31/2006
• Status: Expired due to Fees

• Current Assignee: Codman & Shurtleff Incorporated (Johnson & Johnson)
• Original Assignee: Codman & Shurtleff Incorporated (Johnson & Johnson)
• Inventors: Balgobin, Keith
• Primary Examiner(s): Ho; (Jackie) Tan-Uyen T.
• Assistant Examiner(s): MASHACK, MARK F
• Application Number:
  US11/344,989
• Publication Number:
  US 20070179588A1
• Time in Patent Office: 1,526 Days
• Field of Search: 606/108, 606/191, 606/206, 606/198, 606/200, 604/57, 604/94.01, 604/195, 623/1.11
• US Class Current: 606/200
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 2017/00477 Coupling A61B2017/0046 takes precedence
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device

Abstract

Therapeutic devices, especially vaso-occlusive devices or embolic coils, are delivered by an apparatus that includes a pullwire having a tine or tines that have an offset orientation that engages a therapeutic device. The pullwire passes through an opening of a headpiece. When the pullwire moves in a relative proximal direction, the tine moves toward a straight-line orientation, and the therapeutic device is liberated from the tine and from the pullwire. At this state, the therapeutic device is ready for deployment at a desired intraluminal location.

Claims

1. A system for intraluminal delivery of a therapeutic device, comprising:

an elongated guide tube for intraluminal deployment;

a pusher sized and shaped to be slidably positioned within said guide tube, said pusher having a longitudinal axis, an interior lumen wall and a distal end portion;

a therapeutic device with a proximal end portion and a distal end portion, the proximal end portion of the therapeutic device and the distal end portion of the pusher are adapted for engagement at an abutment location therebetween;

a headpiece disk at said abutment location, said headpiece disk including a draw-down opening, said draw-down opening having a longitudinal axis being coaxial with said longitudinal axis of the pusher, and the draw-down opening having an outer perimeter that is radially inwardly spaced away from the lumen wall of said pusher;

a pullwire having a longitudinal axis generally coaxial with said longitudinal axis of said draw-down opening and positioned through said draw-down opening of the headpiece disk, said pullwire having a proximal end portion and a distal end portion, said pullwire further including at least one tine present at said distal end portion of the pullwire, said tine having a generally straight-line orientation at which the tine engages the outer perimeter of the draw-down opening and an offset orientation at which the tine engages said therapeutic device; and

said pullwire and said draw-down opening are sized and shaped relative to each other such that said tine moves from said offset orientation toward said generally straight-line orientation when said pullwire moves through said draw-down opening of the headpiece disk in a proximal direction and said tine slidably engages the outer perimeter of the draw-down opening thereby disengaging said tine from said therapeutic device.

2. The system of claim 1, wherein said headpiece disk is a component of the therapeutic device and is positioned at the proximal end portion of the therapeutic device.

3. The system of claim 1, wherein said headpiece disk is a component of the pusher and is located at the distal end portion of the pusher.

4. The system of claim 1, wherein said therapeutic device is an embolic coil.

5. The system of claim 1, wherein said tine of the pullwire is formed from a shape memory alloy.

6. The system of claim 5, wherein said tine of the pullwire is formed from a nickel titanium alloy.

7. The system of claim 1, wherein said tine is integrally formed with the rest of the pullwire.

8. The system of claim 1, including more than one said tine, each being of substantially the same length.

9. The system of claim 8, wherein said tines have substantially the same offset orientation.

10. The system of claim 1, wherein said tine is resilient such that same returns to said offset orientation after being at said generally straight-line orientation.

16. The system of claim 1, wherein said therapeutic device is vaso-occlusive.

11. An apparatus for intraluminal delivery of a therapeutic device, comprising:

a pusher sized and shaped for intraluminal delivery, said pusher having a longitudinal axis, an interior lumen wall and a distal end portion;

a therapeutic device with a proximal end portion and a distal end portion, the proximal end portion of the therapeutic device and the distal end portion of the pusher are adapted for engagement at an abutment location therebetween;

a headpiece disk at said abutment location, said headpiece disk including a draw-down opening, said draw-down opening having a longitudinal axis being generally coaxial with said longitudinal axis of the pusher, and the draw-down opening having an outer perimeter that is radially inwardly spaced away from the lumen wall of said pusher;

a pullwire having a longitudinal axis generally coaxial with said longitudinal axis of said draw-down opening and positioned through said draw-down opening of the headpiece disk, said pullwire having a proximal end portion and a distal end portion, said pullwire further including at least one tine present at said distal end portion of the pullwire, said tine having a generally straight-line orientation at which the tine engages the outer perimeter of the draw-down opening and an offset orientation at which the tine engages said therapeutic device; and

said pullwire and said draw-down opening are sized and shaped relative to each other such that said tine moves from said offset orientation toward said generally straight-line orientation when said pullwire moves through said draw-down opening of the headpiece disk in a proximal direction and said tine slidably engages the outer perimeter of the draw-down opening thereby disengaging said tine from said therapeutic device.

12. The apparatus of claim 11, wherein said headpiece disk is a component of the therapeutic device and is positioned at the proximal end portion of the therapeutic device.

13. The apparatus of claim 11, wherein said headpiece disk is a component of the pusher and is located at the distal end portion of the pusher.

14. The apparatus of claim 11, wherein said therapeutic device is an embolic coil.

15. The apparatus of claim 11, wherein said tine of the pullwire is formed from a shape memory alloy.