Method and apparatus for transferring heat to or from an organ or tissue container
First Claim
Patent Images
1. Apparatus for holding an organ or a tissue for at least one of perfusion, storage, diagnosis and transport of the organ or tissue, comprising:
- an organ or tissue transporter being configured to perfuse an organ or a tissue;
a portable housing having one or more heat transfer surfaces;
a compartment within the transporter having one or more heat transfer surfaces arranged on an outer surface of the compartment to transfer heat between a cooling source contained within the compartment and at least a part of one of the one or more heat transfer surfaces of the portable housing, the compartment being liquid-tight and preventing contact between a liquid contained within the compartment and the portable housing; and
an organ or tissue supporting surface configured to support the organ or tissue within said portable housing,wherein the portable housing is configured to be received by the transporter and wherein at least a portion of at least one of the one or more heat transfer surfaces of the compartment is in contact with at least a portion of at least one of the one or more heat transfer surfaces of the portable housing to allow effective heat transfer to or from the contents of the portable housing.
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Accused Products
Abstract
An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The apparatus and methods include the cassette and transporter with heat transfer surfaces arranged to transfer heat between a cooling source in said transporter and the heat transfer surfaces of the cassette.
147 Citations
62 Claims
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1. Apparatus for holding an organ or a tissue for at least one of perfusion, storage, diagnosis and transport of the organ or tissue, comprising:
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an organ or tissue transporter being configured to perfuse an organ or a tissue; a portable housing having one or more heat transfer surfaces; a compartment within the transporter having one or more heat transfer surfaces arranged on an outer surface of the compartment to transfer heat between a cooling source contained within the compartment and at least a part of one of the one or more heat transfer surfaces of the portable housing, the compartment being liquid-tight and preventing contact between a liquid contained within the compartment and the portable housing; and an organ or tissue supporting surface configured to support the organ or tissue within said portable housing, wherein the portable housing is configured to be received by the transporter and wherein at least a portion of at least one of the one or more heat transfer surfaces of the compartment is in contact with at least a portion of at least one of the one or more heat transfer surfaces of the portable housing to allow effective heat transfer to or from the contents of the portable housing. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A method of transporting an organ or a tissue, comprising:
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placing the organ or tissue in a portable housing, the portable housing having one or more heat transfer surfaces; placing the portable housing containing the organ or tissue in a compartment of a transporter configured to receive the portable housing and configured to perfuse the organ or tissue, the compartment having one or more heat transfer surfaces arranged on an outer surface of the compartment, the compartment being liquid-tight and preventing contact between a liquid contained within the compartment and the portable housing, wherein at least a portion of at least one of the one or more heat transfer surfaces of the compartment is in contact with at least a portion of at least one of the one or more heat transfer surfaces of the portable housing; transferring heat between a cooling source contained within the compartment, via at least a part of one of the one or more heat transfer surfaces of the compartment, to or from the contents of the portable housing; and transporting the organ in said portable housing in said transporter. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41)
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42. A system for holding an organ or tissue for transport of the organ or tissue, comprising:
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an organ or tissue transporter; a portable housing having one or more heat transfer surfaces; a compartment within the transporter having one or more heat transfer surfaces arranged on an outer surface of the compartment to transfer heat between a cooling source contained within the compartment and at least a part of one of the one or more heat transfer surfaces of the portable housing, the compartment being liquid-tight and preventing contact between a liquid contained within the compartment and the portable housing; and an organ or tissue supporting surface configured to support an organ or tissue within said portable housing; wherein the portable housing is configured to be received by the transporter and wherein at least a portion of at least one of the one or more heat transfer surfaces of the compartment is in contact with at least a portion of at least one of the one or more heat transfer surfaces of the portable housing to allow effective heat transfer to or from the contents of the portable housing, wherein the portable housing includes openings configured to allow tubing to pass through said openings and be connected to the organ, the tubing being configured to pass through the openings when the portable housing is mated with the compartment and being configured to be mated with the portable housing when the portable housing is removed from the compartment, and wherein the portable housing includes a handle that is accessible when the portable housing is mated with the compartment. - View Dependent Claims (43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60)
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61. Apparatus for holding an organ or a tissue for at least one of perfusion, storage, diagnosis and transport of the organ or tissue, comprising:
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an organ or tissue transporter; a portable housing having one or more heat transfer surfaces; a compartment within the transporter having one or more heat transfer surfaces arranged on an outer surface of the compartment to transfer heat between a cooling source contained within the compartment and at least a part of one of the one or more heat transfer surfaces of the portable housing, the compartment being liquid-tight and preventing contact between a liquid contained within the compartment and the portable housing; and an organ or tissue supporting surface configured to support the organ or tissue within said portable housing, wherein the portable housing is configured to be received by the transporter and wherein at least a portion of at least one of the one or more heat transfer surfaces of the compartment is in contact with at least a portion of at least one of the one or more heat transfer surfaces of the portable housing to allow effective heat transfer to or from the contents of the portable housing, wherein the portable housing includes openings configured to allow tubing to pass through said openings and be connected to the organ or tissue, and wherein the tubing can pass through the openings when the portable housing is mated with the compartment.
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62. A method of transporting an organ or a tissue, comprising:
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placing the organ or tissue in a portable housing, the portable housing having one or more heat transfer surfaces; placing the portable housing containing the organ or tissue in a compartment of a transporter configured to receive the portable housing, the compartment having one or more heat transfer surfaces arranged on an outer surface of the compartment, the compartment being liquid-tight and preventing contact between a liquid contained within the compartment and the portable housing, wherein at least a portion of at least one of the one or more heat transfer surfaces of the compartment is in contact with at least a portion of at least one of the one or more heat transfer surfaces of the portable housing; transferring heat between a cooling source contained within the compartment, via at least a part of one of the one or more heat transfer surfaces of the compartment, to or from the contents of the portable housing; and transporting the organ in said portable housing in said transporter, wherein the portable housing includes openings configured to allow tubing to pass through said openings and be connected to the organ, and wherein the tubing can pass through the openings when the portable housing is mated with the compartment.
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Specification