Hollow core optical ring resonator sensor, sensing methods, and methods of fabrication
First Claim
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1. A hollow core optical ring resonator sensor comprising:
- (a) an optical tube with an outer surface and an inner surface, whereby the inner surface forms a hollow core, wherein the outer and inner surfaces of the optical tube are smooth;
(b) an outer diameter of the optical tube ranging from about 10 μ
m to about 1000 μ
m; and
,(c) a wall thickness of the optical tube ranging from about 1 μ
m to about 20 μ
m, wherein the optical tube is dimensioned so there will be a differential pressure below 10 Pa when a sample is present in the hollow core.
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Abstract
The present invention is directed to hollow core optical ring resonators (HCORRs), methods of fabricating HCORRs, and methods of using HCORRs in sensing applications. In particular, the evanescent field and whispering gallery modes of the HCORRs may be used to detect a target analyte within the hollow core of the HCORR. Other features of the present invention include utilizing the HCORR as part of a multiplex sensing device, including using the HCORR in capillary electrophoresis and chromatography applications.
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Citations
24 Claims
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1. A hollow core optical ring resonator sensor comprising:
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(a) an optical tube with an outer surface and an inner surface, whereby the inner surface forms a hollow core, wherein the outer and inner surfaces of the optical tube are smooth; (b) an outer diameter of the optical tube ranging from about 10 μ
m to about 1000 μ
m; and
,(c) a wall thickness of the optical tube ranging from about 1 μ
m to about 20 μ
m, wherein the optical tube is dimensioned so there will be a differential pressure below 10 Pa when a sample is present in the hollow core. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A hollow core optical ring resonator sensing architecture comprising:
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(a) an optical tube with a hollow core, with the optical tube having an outer diameter ranging from about 10 μ
m to about 1000 μ
m and a wall thickness ranging from about 1 μ
m to about 20 μ
m, wherein the optical tube is dimensioned so there will be a differential pressure below 10 Pa when a sample is present in the hollow core;(b) a guided light source in contact with the optical tube of (a), wherein the light source produces an optical signal in the optical tube, the optical signal comprising whispering gallery modes and an associated evanescent field; and (c) an optical signal that in communication with the interior of the hollow core, wherein the presence of a target analyte in the hollow core will cause modulations in the optical signal; and (d) a photodetector that is in contact with the resulting optical signal. - View Dependent Claims (18)
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19. A method of fabricating a hollow core optical ring sensor comprising:
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(a) mechanically pulling an optical tube under high temperature, thereby producing an optical tube with an outer diameter ranging from about 10 μ
m to about 1000 μ
m; and
,(b) etching a surface of the optical tube with a solution comprising acids, thereby producing a wall thickness ranging from about 1 μ
m to about 20 μ
m, wherein the optical tube is dimensioned so there will be a differential pressure below 10 Pa when a sample is present in the hollow core.
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20. A method of fabricating a hollow core optical ring comprising:
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(a) mechanically pulling an optical tube under high temperature, thereby producing an optical tube with an outer diameter ranging from about 10 μ
m to about 1000 μ
m; and(b) ablating a surface of the optical tube with a laser, thereby producing a wall thickness ranging from about 1 μ
m to about 20 μ
m, wherein the optical tube is dimensioned so there will be a differential pressure below 10 Pa when a sample is present in the hollow core.
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21. A method of detecting a target analyte comprising the following steps:
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(a) contacting a test sample to the inner surface of an optical tube with a hollow core, with the optical tube having an outer diameter ranging from about 10 μ
m to about 1000 μ
m and a wall thickness ranging from about 1 μ
m to about 20 μ
m, wherein the optical tube is dimensioned so there will be a differential pressure below 10 Pa when a sample is present in the hollow core;(b) contacting a light of a known wavelength to the optical tube with a hollow core, thereby producing an associated evanescent field which is capable of extending into the hollow core, and an associated whispering gallery mode that is measurable as an optical signal output; (c) measuring the optical signal output; and
,(d) detecting the presence of a target analyte in the test sample by comparing the optical signal output and the guided light input.
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22. A hollow core optical ring resonator sensor system comprising:
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(a) an optical tube with a hollow core, with the optical tube having an outer diameter ranging from about 10 μ
m to about 1000 μ
m and a wall thickness ranging from about 1 μ
m to about 20 μ
m, wherein the optical tube is dimensioned so there will be a differential pressure below 10 Pa when a sample is present in the hollow core;(b) a light source capable of emitting light at a single wavelength or plurality of wavelengths, wherein the light source is positioned to emit light into the optical tube, the optical tube emitting at least a portion of the light therefrom, and (c) a detector detecting the light emitted from the optical tube.
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23. A hollow core optical ring resonator sensor comprising:
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(a) an optical tube with an outer surface and an inner surface, whereby the inner surface forms a hollow core, wherein the outer and inner surfaces of the optical tube are smooth; (b) an outer diameter of the optical tube ranging from about 10 μ
m to about 1000 μ
m; and
,(c) a wall thickness of the optical tube ranging from about 1 μ
m to about 20 μ
m, wherein the optical tube is dimensioned so that a light signal in the optical ring resonator will penetrate and interact with the hollow core, and wherein the optical tube is dimensioned so there will be a differential pressure below 10 Pa when a sample is present in the hollow core. - View Dependent Claims (24)
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Specification