Emboli filtration system and methods of use

• US 7,699,866 B2
• Filed: 04/15/2005
• Issued: 04/20/2010
• Est. Priority Date: 07/16/1999
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Inventors: Pisano, Nicola A., Hogendijk, Michael, Bates, Mark C.
• Primary Examiner(s): Philogene; Pedro
• Application Number:
  US11/106,969
• Publication Number:
  US 20050182440A1
• Time in Patent Office: 1,831 Days
• Field of Search: 606/200, 606/127, 606/114, 606/159, 606/110, 606/113, 606/167, 606/194, 606/108, 604/523, 604/164.13
• US Class Current: 606/200
• CPC Class Codes: A61F 2/0108 Both ends closed, i.e. legs gathered at both ends
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/015 Stop means therefor
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61M 2025/09183 having tools at the distal tip
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

An emboli filtration apparatus is provided comprising a guide wire having a filter element captured thereon, so that the guide wire is free to rotate and translate while the filter element remains stationary. The apparatus allows for movement and rotation of the guide wire as devices are advanced over it to treat occlusive disease, substantially without dislodging the filter element. In a preferred embodiment, the guide wire comprises a proximal stop configured to reposition the filter element during a medical procedure without having to remove or insert additional interventional devices.

Claims

1. Apparatus for filtering emboli from blood flowing through a vessel, the apparatus comprising:

a guide wire having proximal and distal regions, and proximal and distal stops on the distal region and

a filter element rotatable and translatable relative to the guide wire,

wherein the apparatus has a first configuration in which the filter is located proximal of the proximal stop and a second configuration in which the filter has been advanced in vitro to a position distal of the proximal stop, the proximal stop thereafter prohibiting proximal retraction of the filter element over the proximal stop, and

further wherein the proximal stop comprises at least one depressible tab having proximal and distal ends, wherein the proximal end is affixed to the guide wire.

2. The apparatus of claim 1 wherein the distal stop limits translation of the filter element in a distal direction.

3. The apparatus of claim 1 wherein the proximal stop and distal stop are spaced apart such a distance that the filter element, when deployed therebetween, will not be disturbed by incidental longitudinal movements of the guide wire.

4. The apparatus of claim 1 wherein the proximal stop is configured to abut against a proximal portion of the filter element, after the filter element is moved to the distal region, when the guide wire is advanced.

5. The apparatus of claim 1 further comprising a plurality of self-expanding struts coupled between a capture ring and a filter sac.

6. The apparatus of claim 1 wherein the distal end of the depressible tab is biased radially outward from the guide wire in a relaxed state.

7. The apparatus of claim 6 wherein the distal end of the depressible tab is configured to abut against the filter element once the filter element is moved to the distal region.

8. The apparatus of claim 6 wherein the depressible tab further comprises a contracted state in which the distal end is substantially flush with an exterior surface of the guide wire.

9. The apparatus of claim 1 wherein the depressible tab is configured to facilitate distal advancement of the filter element over the proximal stop in the contracted state.

10. A method for filtering emboli from blood flowing through a vessel, the method comprising:

providing an apparatus comprising a guide wire having a distal region including a distal stop, a proximal stop disposed proximal the distal stop, and a filter element translatable and rotatable relative to the guide wire, wherein the filter element is initially disposed proximal of the proximal stop, the proximal stop comprising at least one depressible tab having a proximal end affixed to the guide wire and a distal end, the method further comprising;

providing the depressible tab in a relaxed state wherein the distal end is biased radially outward from an exterior surface of the guide wire;

transluminally inserting the guide wire into a vessel;

distally advancing the filter element in a contracted state over the depressible tab to cause the distal end of the depressible tab to be substantially flush with the exterior surface of the guide wire;

returning the depressible tab to the relaxed state after the filter element is advanced distal of the proximal stop thereby preventing the filter from being retracted proximally; and

deploying the filter element, distal of the proximal stop and proximal of the distal stop, to engage a wall of the vessel and filter emboli out of blood flowing through the vessel.

11. The method of claim 10 further comprising advancing a treatment device along the guide wire to treat a portion of the vessel proximal of the location of the filter element, wherein incidental rotation or translation of the guide wire relative to the filter element does not displace the filter element.

12. The method of claim 11 further comprising a step of, after use of the treatment device is completed, pulling the guide wire proximally so that the distal stop engages the filter element and causes the filter element to return to the contracted state.

13. The method of claim 10 further comprising:

distally advancing the guide wire; and

causing the proximal stop to abut and urge the filter element distally.