2-methylene-1alpha,25-dihydroxy-18,19,21-trinorvitamin D3 and uses thereof
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Abstract
Compounds of formula I are provided where X1, X2 and X3 are independently selected from H or hydroxy protecting groups. Such compounds are used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions.
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Citations
27 Claims
- 1. A compound having the formula I
- 17. A compound having the formula II
- 21. A method of treating obesity of an animal, inhibiting adipocyte differentiation, inhibiting SCD-1 gene transcription, and/or reducing body fat in an animal comprising administering to an animal in need thereof an effective amount of a compound having the formula:
Specification