Please download the dossier by clicking on the dossier button x
×

Methods for assessing a physiological state of a mammalian retina

  • US 7,706,863 B2
  • Filed: 08/26/2004
  • Issued: 04/27/2010
  • Est. Priority Date: 01/21/2004
  • Status: Active Grant
First Claim
Patent Images

1. A method for assessing a physiological state of a mammalian retina in vivo, the method comprising the steps of:

  • (a) irradiating a portion of a mammalian retina, in vivo, with short-pulse light from a laser having a wavelength in the range of from 600 nm to 1000 nm at an intensity sufficient to stimulate two-photon-induced fluorescence in the retina;

    (b) detecting the two-photon-induced fluorescence from the retina using a photon detector to produce a pixel; and

    (c) repeating steps (a) and (b) to collect a plurality of pixels,(d) producing an image from the plurality of pixels, wherein the image visualizes at least one retinosome; and

    (e) assessing the physiological state of the retina based on the at least one retinosome.

View all claims
  • 3 Assignments
Timeline View
Assignment View
    ×
    ×