System and method for detecting artifactual hemodynamic waveform data

• US 7,708,693 B2
• Filed: 01/27/2005
• Issued: 05/04/2010
• Est. Priority Date: 01/27/2005
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Igel, David A., Choi, Mark, Whitman, Teresa A., Bennett, Tommy D., Hill, Michael R. S.
• Primary Examiner(s): Marmor, II; Charles A
• Assistant Examiner(s): Natnithithadha; Navin
• Application Number:
  US11/044,618
• Publication Number:
  US 20060167360A1
• Time in Patent Office: 1,923 Days
• Field of Search: 600/481, 600483-486, 600/488, 600490-504, 600508-528, 600/300, 600/301, 600/561
• US Class Current: 600/485
• CPC Class Codes: A61B 5/02108 from analysis of pulse wave characteristics
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00

Abstract

A system and method for cardiovascular analysis includes an implantable medical device capable of generating hemodynamic pressure waveform data based upon sensed pressure. Hemodynamic waveform data is analyzed to identify artifactual data represented in the hemodynamic waveform.

Claims

1. A system for hemodynamic waveform data trend analysis, the system comprising:

means for generating hemodynamic pressure waveform data that corresponds to sensed hemodynamic pressure over time;

means for analyzing the hemodynamic pressure waveform data to determine hemodynamic waveform parameters, including a systolic pressure and a diastolic pressure for a cardiovascular pulse cycle; and

means for identifying multiple types of artifactual data in a series of hemodynamic waveforms based upon hemodynamic waveforms in the series and for generating trend data using hemodynamic waveforms containing the identified types of artifactual data, using only those of the hemodynamic parameters that are unaffected by the identified artifactual data.

2. A system according to claim 1 and further comprising means for excluding from the trend data any hemodynamic pressure waveform data for a cardiovascular pulse cycle containing artifactual data.

3. A system according to claim 1 and further comprising means for excluding artifactual data from hemodynamic waveform data containing the artifactual data.

4. A system according to claim 1 and further comprising means for creating dP/dt plots representative of the first derivatives of the hemodynamic pressure waveform data with respect to time, and determining maximum and minimum values for each dP/dt plot.

5. A system according to claim 4, wherein the artifactual data corresponds to any maximum dP/dt value greater than a predetermined value.

6. A system according to claim 5, wherein the predetermined value has a magnitude of about 512 mmHg/sec.

7. A system according to claim 1, wherein hemodynamic pressure waveform data having a pulse width less than a predetermined time period are identified as containing artifactual data.

8. A system according to claim 7, wherein the predetermined time period has a magnitude of about 74.2 milliseconds.

9. A system according to claim 1, wherein hemodynamic pressure waveform data having a negative average pressure value is identified as containing artifactual data.

10. A system according to claim 1, wherein hemodynamic pressure waveform data having a diastolic pressure value greater than a predetermined value is identified as containing artifactual data.

11. A system according to claim 10, wherein the predetermined value is about 50 mmHg.

12. A system according to claim 1, wherein hemodynamic pressure waveform data having a substantially constant pressure value for longer than a predetermined time during a designated period of pressure sensing is identified as containing artifactual data.

13. A system according to claim 12, wherein the predetermined time is about 78 milliseconds, and wherein the designated period of pressure sensing is from about zero to about 150 milliseconds of pressure sensing.

14. A system according to claim 12, wherein the predetermined time is about 150 milliseconds, and wherein the designated period of pressure sensing is from about 200 to about 400 milliseconds of pressure sensing.

15. A system according to claim 1, wherein the hemodynamic pressure waveform data includes a first sample and a last sample, and wherein any hemodynamic pressure waveform data having first and last samples with pressure values that differ by more than a predetermined value are identified as containing artifactual data.

16. A system according to claim 15, wherein the predetermined value is about 30 mmHg.