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Pharmaceutical formulation

  • US 7,709,536 B2
  • Filed: 09/16/2005
  • Issued: 05/04/2010
  • Est. Priority Date: 08/14/2002
  • Status: Expired due to Term
First Claim
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1. A liquid pharmaceutical formulation, for use in the administration of a lipophilic medicament via a mucosal surface, comprising:

  • at least one lipophilic medicament, a solvent and co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulation, the formulation is absent of a self emulsifying agent and a fluorinated propellant, and the formulation has a water content of less than 5% and the formulation is packaged for delivery as a spray, wherein the lipophilic medicament comprises tetrahydrocannabinol (THC) and cannabidiol (CBD), wherein the lipophilic medicament is at least one extract from at least one cannabis plant, and wherein the extract from at least one cannabis plant is a botanical drug substance.

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