Process and device for the dose dispensing of a radioactive solution

• US 7,712,491 B2
• Filed: 07/02/2004
• Issued: 05/11/2010
• Est. Priority Date: 07/02/2003
• Status: Expired due to Fees

• Current Assignee: Henri-Jaques Tochon-Danguy, Stanislav Samuel Poniger
• Original Assignee: Henri-Jaques Tochon-Danguy, Stanislav Samuel Poniger
• Inventors: Tochon-Danguy, Henri-Jaques, Poniger, Stanislav Samuel
• Primary Examiner(s): Huson; Gregory L
• Assistant Examiner(s): NIESZ, JASON KAROL
• Application Number:
  US10/562,766
• Publication Number:
  US 20060151048A1
• Time in Patent Office: 2,139 Days
• Field of Search: 141/97, 141/25, 141/26, 141/27, 141/100, 141/102, 141/104, 141/105, 600/5
• US Class Current: 141/97
• CPC Class Codes: B65B 3/003 Filling medical containers such as ampoules, vials, syringes or the like
• CPC Class Codes: G21F 5/015 for storing radioactive sources, e.g. source carriers for irradiation units; Radioisotope containers

Abstract

An apparatus and method for automatically dispensing a radioactive dose by filling a container, such as a vial or disposable syringe, with a required radioactive dose in a sterile environment; the apparatus being stand alone and radioactive-shielded. The apparatus further includes a control device for accurately dispensing and diluting the required radioactive dose using an online radioactivity measurement, which does not require knowledge of the volumetric radioactivity of the stock solution.

Claims

1. A radioactive dose dispensing apparatus for automatically filling a container with a required radioactive dose in a sterile environment, comprising:

a container for containing a radioactive dose;

means for radiation shielding of said radioactive dose dispensing apparatus;

means for controlling a mix of radioactive stock solution and dilution stock solution for automatically diluting the radioactive stock solution with the dilution stock solution as both the radioactive stock solution and the dilution stock solution simultaneously pass into said container;

means for detecting radioactivity of said mix of radioactive stock solution and dilution stock solution; and

,

means for automating said radioactive dose dispensing apparatus and calculating a required dose for controlling the radioactive dose being dispensed into said container, said means for automating said radioactive dose dispensing apparatus and calculating a required dose comprising a programmable logic controller operable in combination with a radiation detector.

2. The radioactive dose dispensing apparatus according to claim 1, wherein said container is disposable.

3. The radioactive dose dispensing apparatus according to claim 1, further comprising a shielded receptacle for receiving said container.

4. The radioactive dose dispensing apparatus according to claim 1, wherein programmable logic controller is operable via a computer interface.

5. The radioactive dose dispensing apparatus according claim 1, further comprising a disposable tubing assembly for providing a sterile fluid pathway for the dilution stock solution.

6. The radioactive dose dispensing apparatus according claim 1, further comprising pinch valves for switching between the radioactive stock solution and the dilution stock solution.

7. The radioactive dose dispensing apparatus according to claim 1, wherein said container is formed as a plunger-operated syringe.

8. The radioactive dose dispensing apparatus according to claim 7, further comprising drive means for actuating said plunger-operated syringe.

9. The radioactive dose dispensing apparatus according to claim 8, wherein said drive means is a linear drive mechanism for actuating said plunger-operated syringe.