Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces
First Claim
1. A method for disinfecting and/or sterilizing a floor, a table-top, a counter-top, hospital equipment, a wheel chair, or a medical device comprising applying a composition consisting essentially of chlorhexidine and a dye selected from the group consisting of gentian violet and brilliant green to the floor, table-top, counter-top, hospital equipment, wheel chair, or medical device, wherein the molar ratio of chlorhexidine:
- dye in the composition is 1;
1 to 25;
1.
1 Assignment
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Accused Products
Abstract
The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially in-dwelling medical devices to prevent the growth of pathogens in such devices and hence, to prevent infection to patients via such devices are provided. The invention also provides antiseptics that are useful as general surface disinfectants and sterilizers, fluid disinfectants and biocide preservatives.
56 Citations
48 Claims
- 1. A method for disinfecting and/or sterilizing a floor, a table-top, a counter-top, hospital equipment, a wheel chair, or a medical device comprising applying a composition consisting essentially of chlorhexidine and a dye selected from the group consisting of gentian violet and brilliant green to the floor, table-top, counter-top, hospital equipment, wheel chair, or medical device, wherein the molar ratio of chlorhexidine:
-
47. A method for disinfecting and/or sterilizing a floor, a table-top, a counter-top, hospital equipment, a wheel chair, or a medical device comprising applying a composition consisting essentially of:
-
a) chlorhexidine; b) a dye that is gentian violet or brilliant green; and c) one or more additional dyes selected from the group consisting of crystal violet, FD&
C Yellow No. 5, FD&
C Yellow No. 6, D&
C Red NO. 17, FD&
C Red No. 3, D&
C Green No. 6, ethyl violet, FD&
C Blue No. 2, D&
C Yellow No. 1, FD&
C Blue No. 1, and FD&
C Green No. 3 to a floor, table-top, counter-top, hospital equipment, wheel chair, or medical device, wherein the molar ratio of chlorhexidine;
dye in the composition is 1;
1 to 25;
1.
-
-
48. A method for disinfecting and/or sterilizing a floor, a table-top, a counter-top, hospital equipment, a wheel chair, or a medical device comprising applying a composition consisting essentially of:
-
a) a basic reagent that is chlorhexidine; b) a dye that is gentian violet or brilliant green; and c) one or more additional basic reagents selected from the group consisting of a guanidium, a biguanide, a bipyridine, a phenoxide antiseptic, an alkyl oxide, a thiol, a halide, an aliphatic amino, and an aromatic amine to a floor, table-top, counter-top, hospital equipment, wheel chair, or medical device, wherein the molar ratio of chlorhexidine;
dye in the composition is 1;
1 to 25;
1.
-
Specification