Field-deployable concussion detector

• US 7,720,530 B2
• Filed: 03/03/2008
• Issued: 05/18/2010
• Est. Priority Date: 08/02/2005
• Status: Active Grant

• Current Assignee: Brainscope SPV LLC
• Original Assignee: Brainscope Company Inc.
• Inventors: Causevic, Elvir
• Primary Examiner(s): Nasser; Robert L
• Application Number:
  US12/041,106
• Publication Number:
  US 20080208073A1
• Time in Patent Office: 806 Days
• Field of Search: None
• US Class Current: 600/544
• CPC Class Codes: A61B 2560/0431 Portable apparatus, e.g. comprising a handle or case
• CPC Class Codes: A61B 5/374 Detecting the frequency distribution of signals, e.g. detecting delta, theta, alpha, beta or gamma waves
• CPC Class Codes: A61B 5/377 using evoked responses
• CPC Class Codes: A61B 5/4076 Diagnosing or monitoring particular conditions of the nervous system A61B5/4821, A61B5/4824 take precedence
• CPC Class Codes: A61B 5/726 using Wavelet transforms

Abstract

A method and apparatus for providing an on-site diagnosis of a subject to determine the presence and/or severity of a concussion is provided. The method includes placing an electrode set coupled to a handheld base unit on the subject'"'"'s head, acquiring brain electrical signals from the subject through the electrode set, processing the acquired brain electrical signals using a signal processing algorithm stored in a memory of the base unit, determining the presence and/or severity of a concussion from the processed signals, indicating the presence and/or severity of a concussion on the handheld base unit, and determining a course of treatment for the subject based on the indication.

Claims

1. A portable device for detecting the presence and severity of a concussion in a subject, comprising:

a headset comprising a plurality of brain-electrical-signal-detecting electrodes; and

a portable base unit operably coupled to the headset, the base unit comprising;

a processor;

a memory, the memory containing instructions for causing the processor to perform, at least in part, a non-linear signal processing algorithm on the detected signals; and

an indicator for providing an indication of the presence and severity of a concussion.

2. The portable device according to claim 1, wherein the detected signals comprise at least one of spontaneous or evoked signals.

3. The portable device according to claim 1, wherein the non-linear signal processing algorithm denoises the detected signals;

extracts features from the denoised signals;

builds discriminant functions for classifying the extracted features; and

detects the presence and severity of a concussion based on the classified features.

4. The portable device according to claim 3, wherein the non-linear signal processing algorithm comprises at least one of a wavelet, a wavelet packet processing algorithm, a diffusion geometry processing algorithm, or a fractal processing algorithm.

5. The portable device according to claim 1, wherein the memory further comprises interactive instructions for using and operating the device.

6. The portable device according to claim 1, wherein the indicator comprises a visual display.

7. The portable device according to claim 6, wherein the visual display comprises a color-coded indication.

8. The portable device according to claim 7, wherein the color-coded indication comprises:

a red indication, which is displayed if the concussion is present and serious;

an orange indication, which is displayed if a concussion is likely present, and more tests are required to be performed on the subject; and

a green indication, which is displayed if there is no concussion.

9. The portable device according to claim 6, wherein the visual display comprises a liquid crystal display (LCD) screen, the LCD screen capable of displaying an indication of the presence of a concussion, the severity of the concussion, and a visual of the subject'"'"'s brain showing a region of the brain having the concussion.

10. The portable device according to claim 9, wherein the visual display further displays interactive instructions, stored in the memory, for using and operating the device.

11. The portable device according to claim 1, further comprising:

at least one of a video camera or a microphone operably coupled to the handheld base unit for recording the subject, the recording being stored in the memory, wherein

the memory contains instructions for causing the processor to detect predetermined features from the stored recording, the detected features being processed by the signal processing algorithm.

12. A method for providing an on-site diagnosis of a subject to determine the presence and severity of a concussion, comprising:

placing an electrode set coupled to a handheld base unit on the subject'"'"'s head;

acquiring brain electrical signals from the subject through the electrode set;

processing, by a processor in the base unit, the acquired brain electrical signals using, at least in part, a non-linear signal processing algorithm stored in a memory of the base unit;

determining the presence and severity of a concussion from the processed signals;

indicating the presence and severity of a concussion on the handheld base unit; and

determining a course of treatment for the subject based on the indication.

13. The method according to claim 12, further comprising:

storing the acquired brain electrical signals; and

wirelessly transmitting the stored signals to a remote database.

14. The method according to claim 12, wherein determining the presence and severity of a concussion further comprises performing additional tests on the subject.

15. The method according to claim 14, wherein performing the additional tests includes performing at least one of recording at least one of audio or video of the subject and detecting predetermined features, performing neurocognitive interactive tests, performing balance tests, or monitoring the consciousness of the subject.

16. The method of claim 12, wherein determining the presence and severity of a concussion further comprises generating a Concussion index.

17. The method of claim 16, wherein the Concussion Index is generated by the processor based on the severity of symptoms for concussions suffered by the subject.

18. The method of claim 17, further comprising:

storing the generated Concussion Index; and

wirelessly transmitting the stored Concussion Index to a remote database.

19. The method according to claim 12, wherein acquiring brain signals comprises acquiring at least one of spontaneous or evoked signals.

20. The method according to claim 12, wherein processing the acquired signals comprises:

denoising the acquired signals;

extracting desired features from the denoised signals;

building discriminant functions for classifying the extracted features;

classifying the extracted features; and

indicating the presence and severity of a concussion based on the classified features.

21. The method according to claim 12, wherein processing the acquired signals using the non-linear signal processing algorithm comprises performing at least one of a wavelet, a wavelet packet processing algorithm, a diffusion geometry processing algorithm, or a fractal processing algorithm on the acquired signals.

22. The method according to claim 12, wherein indicating the presence and severity of a concussion on the handheld base unit comprises:

displaying a red indication if the head injury is present and serious;

displaying an orange indication if the head injury concussion is likely present but more tests are required to be performed on the subject; and

displaying a green indication if there is no concussion.

23. The method according to claim 12, wherein indicating the presence and severity of a concussion on the handheld base unit comprises:

displaying an indication of a concussion;

displaying the severity of the concussion; and

displaying a location of the concussion.

24. The method according to claim 12, further comprising:

displaying interactive instructions for placing the electrode set on the subject'"'"'s head, acquiring the brain electrical signals from the subject, and determining the presence and severity of a concussion.

25. The method according to claim 12, further comprising determining the presence and severity of a concussion over time, indicating the presence and severity of a concussion on the handheld base unit over time, and then determining a course of treatment for the subject based on a change in the indication over time.

26. A method for determining if a subject has suffered a concussion using a portable handheld device, comprising:

acquiring brain electrical signals from the subject using an electrode set operably coupled to the handheld device;

processing the acquired signals using, at least in part, a non-linear signal processing algorithm;

determining if the subject has a concussion using the processed signals;

determining the severity of the concussion using the processed signals; and

indicating the determination and the severity on the portable handheld device.

27. A portable handheld device for detecting the presence and/or severity of a concussion in a subject, comprising:

a headset comprising a plurality of brain-electrical-signal-detecting electrodes and means for evoking neurological potentials; and

a handheld base unit operably coupled to the headset, the base unit comprising;

a processor;

a memory, the memory containing instructions for causing the processor to perform a signal processing algorithm on the detected signals;

a display, the display providing a visual display of the presence and/or severity of a concussion;

at least one of a video or audio recording device for recording at least one of audio or video of the subject, the memory containing instructions for causing the processor to analyze the recorded at least one of audio or video and extract features from the at least one of audio or video recordings, the extracted features being used by the processor in the signal processing algorithm; and

a wireless communication device for transmitting the detected and processed signals to a remote database.

28. A portable handheld device for detecting the presence and severity of a concussion in a subject, comprising:

a headset comprising a plurality of neurological signal-detecting electrodes and means for evoking neurological potentials; and

a handheld base unit operably coupled to the headset, the base unit comprising;

a processor;

a memory, the memory containing instructions for causing the processor to perform, at least in part, a non-linear signal processing algorithm on the detected signals; and

a display, the display providing a visual display of the presence and severity of a concussion, wherein the display provides a color-coded indication of the presence and/or severity of a concussion, the color-coded indication comprising;

a red indication, which is displayed if the concussion is present and serious;

an orange indication, which is displayed if a concussion is likely present, and more tests are required to be performed on the subject; and

a green indication, which is displayed if there is no concussion.

29. A method for providing an on-site diagnosis of a subject to determine the presence and/or severity of a concussion, comprising:

placing an electrode set coupled to a handheld base unit on the subject'"'"'s head;

acquiring brain electrical signals from the subject through the electrode set;

processing, by a processor in the base unit, the acquired brain electrical signals using a signal processing algorithm stored in a memory of the base unit;

determining the presence and/or severity of a concussion from the processed signals;

generating a Concussion Index based on a severity of symptoms for concussions suffered by the subject; and

indicating the presence and/or severity of a concussion on the handheld base unit.

30. A portable device for detecting the presence and severity of a traumatic brain injury in a subject, comprising:

a headset comprising a plurality of brain-electrical-signal-detecting electrodes; and

a portable base unit operably coupled to the headset, the base unit comprising;

a processor;

a memory, the memory containing instructions for causing the processor to perform, at least in part, a non-linear signal processing algorithm on the detected signals; and

an indicator for providing an indication of the presence and severity of a traumatic brain injury.