System, device, and method for mixing a substance with a liquid

• US 7,726,362 B2
• Filed: 10/29/2007
• Issued: 06/01/2010
• Est. Priority Date: 10/30/2003
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Demers, Jason A., Gray, Larry B., Dale, James D., McGill, David W., Tracey, Brian
• Primary Examiner(s): Huson; Gregory L
• Assistant Examiner(s): NIESZ, JASON KAROL
• Application Number:
  US11/927,101
• Publication Number:
  US 20080110523A1
• Time in Patent Office: 946 Days
• Field of Search: 141/330, 141/329, 141/19, 141/98, 141/113, 141/285, 141/288, 604/411, 604/519, 604/520, 604 82- 88, 417/46, 417/393, 417/395, 417/394, 417/440
• US Class Current: 141/285
• CPC Class Codes: A61M 1/0281 Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
• CPC Class Codes: A61M 1/36222 Details related to the interface between cassette and machine
• CPC Class Codes: A61M 1/362227 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/36225 with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362261 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/362266 Means for adding solutions or substances to the blood
• CPC Class Codes: A61M 1/3687 Chemical treatment A61M1/3675 takes precedence
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: B01F 33/81 Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
• CPC Class Codes: B01F 33/811 in two or more consecutive, i.e. successive, mixing receptacles or being consecutively arranged
• CPC Class Codes: B01F 35/711 for feeding a mixture of components, i.e. solids in liquid, solids in a gas stream
• CPC Class Codes: B01F 35/715 Feeding the components in several steps, e.g. successive steps

Abstract

A system, device, and method for mixing a substance with a liquid pumps the liquid into a container of the substance to produce a solution. The container may be part of a container assembly including a port assembly for coupling with the container to produce an inlet and/or and outlet port for the container. The container assembly may be received within a receiving chamber for causing the coupling. The solution may be permitted to flow out of the outlet port when the solution rises within the container to a level of the outlet port so that the substance is partially diluted before flowing out of the outlet port.

Claims

1. A system for mixing a substance with a liquid, the system comprising:

a primary container partially filled with the substance and having an inlet and an outlet within the primary container above the substance;

a pump cassette having;

a pump capable of applying positive or negative pressure to a fluid or gas within a chamber of the pump,

a first cassette port in valved communication with the pump chamber for connection to the inlet of the primary container,

a second cassette port in valved communication with the pump chamber for connection to a liquid source, and

a third cassette port in valved communication with the pump chamber for venting air from the pump chamber, and;

a controller for measuring and controlling the volume of liquid introduced into the pump chamber and delivered to the primary container, and for venting air from the pump chamber or liquid flow paths in communication with the pump chamber, wherein;

the pump is capable of adding a specified amount of the liquid to the primary container to produce a combined substance and liquid, causing the combined substance and liquid to rise to the container outlet as the liquid is added, and causing at least a portion of the combined substance and liquid to flow from the primary container through the container outlet.

2. The system as defined by claim 1 further comprising a final container capable of coupling with the outlet and receiving the portion of the combined substance and liquid.

3. The system as defined by claim 1 wherein the liquid is a diluting solution.

4. The system as defined by claim 1 wherein the primary container has a septum to sealingly contain the substance.

5. The system as defined by claim 4 wherein the primary container has a top surface that is formed by the septum, the system further including a hollow spike coupled through the septum to produce the outlet.

6. The system as defined by claim 4 further including a spike assembly capable of piercing through the septum in the primary container, the spike assembly having at least one spike forming the inlet and the outlet.

7. The system of claim 1, wherein the displacement of a flexible membrane adjacent the pump chamber causes pumping of the liquid or air, said displacement occurring through the application of pneumatic pressure to a bezel chamber adjacent the flexible membrane and opposite the pump chamber, the pneumatic pressure being provided by a pneumatic control assembly.

8. The system as defined by claim 4 further including a spike assembly capable of piercing through the septum in the primary container, the spike assembly having a first spike defining the inlet and a second spike defining the outlet.