Pulse wave data analyzing method, system, and program product

• US 7,727,158 B2
• Filed: 10/05/2006
• Issued: 06/01/2010
• Est. Priority Date: 10/06/2005
• Status: Active Grant

• Current Assignee: Konica Minolta Sensing, Inc. (Konica Minolta Inc.)
• Original Assignee: Konica Minolta Sensing, Inc. (Konica Minolta Inc.)
• Inventors: Tsukamoto, Yasumasa, Fukunami, Masatake, Nagai, Yoshiroh, Kitajima, Kazumi
• Primary Examiner(s): Nasser; Robert L
• Assistant Examiner(s): D'ANGELO, MICHAEL J
• Application Number:
  US11/544,050
• Publication Number:
  US 20070123787A1
• Time in Patent Office: 1,335 Days
• Field of Search: 600500-503, 600508-509, 600/516, 600/521
• US Class Current: 600/500
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/02438 with portable devices, e.g. worn by the patient
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval

Abstract

There is provided a pulse wave data analyzing method for extracting vital information out of pulse wave data concerning a living body. The method comprises a noise removal step of: detecting bottom values and peak values along a time axis in a time-series manner out of pulse wave data obtained by sequentially measuring a pulse wave of a subject for a predetermined period; making pairs with respect to the bottom values and the peak values adjacent to each other on the time axis to obtain bottom-to-peak amplitude values along the time axis, the bottom-to-peak amplitude value being a difference between the bottom value and the peak value in each of the pairs; and comparing each set of the two bottom-to-peak amplitude values adjacent to each other along the time axis to remove the bottom value and the peak value relating to the smaller bottom-to-peak amplitude value in the each set as a noise, if a ratio of the one of the two bottom-to-peak amplitude values to the other one of the two bottom-to-peak amplitude values is larger than a predetermined value.

Claims

1. A method for operating a pulse wave data analyzer to extract vital information out of pulse wave data concerning a living body, the pulse wave data analyzer comprising a central processing unit and a digital signal processor, the method for operating comprising the steps of:

employing the pulse wave data analyzer to execute a noise removal step including;

detecting bottom values and peak values along a time axis in a time-series manner out of pulse wave data obtained by sequentially measuring a pulse wave of a subject for a predetermined period;

making pairs with respect to the bottom values and the peak values adjacent to each other on the time axis to obtain bottom-to-peak amplitude values along the time axis, the bottom-to-peak amplitude values being a difference between the bottom value and the peak value in each of the pairs; and

comparing each set of two bottom-to-peak amplitude values adjacent to each other along the time axis to remove the bottom value and the peak value relating to the smaller bottom-to-peak amplitude value in each set as noise, if a ratio of one of the two bottom-to-peak amplitude values to the other one of the two bottom-to-peak amplitude values is larger than a predetermined value;

employing the pulse wave data analyzer to obtaining peak-to-peak intervals or bottom-to-bottom intervals corresponding to electrocardiogram RR-intervals based on pulse wave data obtained by executing the noise removal step; and

employing the pulse wave data analyzer to output the peak-to-peak intervals or bottom-to-bottom intervals.

2. The method of operating a pulse wave data analyzer according to claim 1, further comprising a step of:

obtaining bottom-to-peak amplitude values based on pulse wave data obtained by executing the noise removal step.

3. The method of operating a pulse wave data analyzer according to claim 1, further comprising a step of:

executing a moving averaging process with respect to the pulse wave data prior to detecting the bottom values and the peak values out of the pulse wave data.

4. The method of operating a pulse wave data analyzer according to claim 1,

wherein the noise removal step is executed one or more times with respect to pulse wave data obtained by executing the noise removal step for the first time.

5. The method of operating a pulse wave data analyzer according to claim 4,

wherein, when the noise removal step is executed more than one time, a threshold value of the amplitude value ratio used in judging whether the bottom value and the peak value are to be removed as noise is changed at least once in repeating the noise removal step.

6. A pulse wave data analyzing system for extracting vital information out of pulse wave data concerning a living body, the system comprising:

a pulse wave detector for obtaining pulse wave information concerning a subject at a predetermined sampling frequency to acquire pulse wave data in association with a time axis; and

a data analyzer for executing a noise removal process to analyze the pulse wave data,

the data analyzer including;

an inflection point detector for detecting bottom values and peak values along the time axis in a time-series manner out of the pulse wave data,

an amplitude value detector for making pairs with respect to the bottom values and the peak values adjacent to each other on the time axis to obtain bottom-to-peak amplitude values along the time axis, the bottom-to-peak amplitude values being a difference between the bottom value and the peak value in each of the pairs,

a noise remover for comparing each set of two bottom-to-peak amplitude values adjacent to each other along the time axis to remove the bottom value and the peak value relating to the smaller bottom-to-peak amplitude value in each set as noise, if a ratio of one of the two bottom-to-peak amplitude values to the other one of the two bottom-to-peak amplitude values is larger than a predetermined value, and

an interval calculator for obtaining peak-to-peak intervals or bottom-to-bottom intervals corresponding to electrocardiogram RR-intervals based on pulse wave data obtained by executing the noise removal by the noise remover.

7. The pulse wave data analyzing system according to claim 6, wherein

the data analyzer includes an amplitude value calculator for obtaining bottom-to-peak amplitude values, as diagnostic information, based on pulse wave data obtained by executing the noise removal by the noise remover.

8. The pulse wave data analyzing system according to claim 6, wherein

the data analyzer includes a moving averaging processor for executing a moving averaging process with respect to the pulse wave data obtained by the pulse wave detector.

9. The pulse wave data analyzing system according to claim 6, wherein

the data analyzer is adapted to control the inflection point detector, the amplitude value detector, and the noise remover to execute the noise removal process one or more times with respect to pulse wave data obtained by executing the noise removal process for the first time.

10. The pulse wave data analyzing system according to claim 9, wherein

the noise remover is adapted to change a threshold value of the amplitude value ratio used in judging whether the bottom value and the peak value are to be removed as noise at least once when the noise removal process is executed more than one time.

11. The pulse wave data analyzing system according to claim 6, further comprising:

a display section for displaying a data analysis result by the data analyzer, wherein

the pulse wave detector, the data analyzer, and the display section are mounted on a device removably attachable to the subject.

12. The pulse wave data analyzing system according to claim 6, further comprising:

a storage section for storing therein the pulse wave data obtained by the pulse wave detector;

a first device including the pulse wave detector and the storage section, the first device being removably attachable to the subject; and

a second device including the data analyzer, wherein the second device is adapted to communicate with the first device to acquire the pulse wave data stored in the storage section.

13. The pulse wave data analyzing system according to claim 6, wherein

the data analyzer is adapted to analyze the pulse wave data on a real-time basis, and control a display section to display analyzed pulse wave information.

14. The pulse wave data analyzing system according to claim 6, wherein

the data analyzer includes a storage section for storing the analyzed pulse wave information therein.

15. A pulse wave data analyzing program product for extracting vital information out of pulse wave data concerning a living body, the program product comprising:

a program which causes a data analyzer for analyzing the pulse wave data to execute steps for;

obtaining pulse wave information concerning a subject at a predetermined sampling frequency to acquire pulse wave data in association with a time axis;

detecting bottom values and peak values along the time axis in a time-series manner out of the pulse wave data;

making pairs with respect to the bottom values and the peak values adjacent to each other on the time axis to obtain bottom-to-peak amplitude values along the time axis, the bottom-to-peak amplitude values being a difference between the bottom value and the peak value in each of the pairs; and

comparing each set of two bottom-to-peak amplitude values adjacent to each other along the time axis to remove the bottom value and the peak value relating to the smaller bottom-to-peak amplitude value in each set as noise, if a ratio of one of the two bottom-to-peak amplitude values to the other one of the two bottom-to-peak amplitude values is larger than a predetermined value;

obtaining peak-to-peak intervals or bottom-to-bottom intervals corresponding to electrocardiogram RR-intervals based on the pulse wave data from which noise has been removed; and

a signal bearing media bearing the program.

16. A pulse wave data analyzing system for extracting vital information out of pulse wave data concerning a living body, the system comprising:

a pulse wave detector for obtaining pulse wave data in association with a time axis; and

a data analyzer for analyzing and removing noise from the pulse wave data, the data analyzer including;

an inflection point detector adapted to detect bottom values and peak values along the time axis in a time-series manner out of the pulse wave data,

an amplitude value detector adapted to identify pairs of bottom values and peak values adjacent to each other on the time axis and calculate bottom-to-peak amplitude values along the time axis, the bottom-to-peak amplitude values being a difference between the bottom value and the peak value in each of the pairs of bottom values and peak values,

a noise remover adapted to calculate a ratio between each set of bottom-to-peak amplitude values adjacent to each other along the time axis and removing the bottom value and the peak value corresponding to the smaller bottom-to-peak amplitude value of each set as noise, if the ratio is larger than a predetermined value, and

an interval calculator adapted to obtain peak-to-peak intervals or bottom-to-bottom intervals corresponding to electrocardiogram RR-intervals based on pulse wave data from which noise has been removed by the noise remover.