Syringe devices and methods for mixing and administering medication

• US 7,731,678 B2
• Filed: 09/28/2005
• Issued: 06/08/2010
• Est. Priority Date: 10/13/2004
• Status: Active Grant

• Current Assignee: Hyprotek, Inc.
• Original Assignee: Hyprotek, Inc.
• Inventors: Tennican, Patrick O., Phipps, L. Myles, Michaelsen, Russell A.
• Primary Examiner(s): Sirmons; Kevin C
• Assistant Examiner(s): Anderson; Michael J
• Application Number:
  US11/238,880
• Publication Number:
  US 20060079834A1
• Time in Patent Office: 1,714 Days
• Field of Search: 604/88, 604/89, 604/228, 604/6.12, 604/414, 604/363, 604/411, 604/82, 604/167.03, 604/246, 604218-221, 604/226, 206/363
• US Class Current: 604/88
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2062 with directional valves
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2086 for fluid filtration
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2005/3117 Means preventing contamination of the medicament compartment of a syringe
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 5/002 Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics needle protection, e.g. caps, A61M5/3202; for sharps A61B50/3001
• CPC Class Codes: A61M 5/204 connected to external reservoirs for multiple refilling
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing

Abstract

The invention includes a device having a chamber within a syringe. A fluid passageway extends through a syringe piston. A valve is associated with the passageway controlling fluid passage through the piston. The invention includes a piercing structure having a head segment and a body portion, with a channel through the body portion and through at least one surface of the head without passing through the tip. In another aspect the invention encompasses a method of preparing an agent for administration to an individual. A first component is provided within a syringe and a second component is provided within a vial. A closed valve is associated with a fluid passageway between the vial and the syringe barrel through a piston. Valve repositioning allows fluid passage and sliding of the piston joins the first and second components. Repeated sliding of the piston mixes the components to produce the medication agent.

Claims

1. A syringe device comprising:

a syringe body comprising a cylindrical housing and a chamber within the housing, the chamber having a longitudinal axis;

a piston comprising a stem, a longitudinal axis, a first end at a first end of the longitudinal axis and a second end opposing the first end, the first end being external to the chamber, the piston comprising a first opening at the first end and a second opening at the second end;

a fluid passageway extending through the first opening, longitudinally through the stem and through the second opening of the piston;

a third opening disposed along the longitudinal axis at a position between the first end and the second end of the piston other than at the first or second end of the piston and traversing the fluid passageway;

a valve, at least a portion of which is inserted within the third opening and orthogonally traversing the fluid passageway, the valve controlling selective fluid passage through the piston and being at least partially insertable within the cylindrical housing of the syringe body;

a piercing structure associated with the first end of the piston, the piercing structure a base having a first diameter, a head portion having a maximum width, and a tube segment extending between the base and the head portion, the tube segment having a second diameter that is smaller than the first diameter and shorter than the maximum width of the head portion; and

a piston seal attached to the second end of the piston.

2. The device of claim 1 further comprising a hollow extension extending from the first end of the piston.

3. The device of claim 2 wherein the hollow extension is cylindrical.

4. The device of claim 2 wherein the hollow extension is configured to house a vial.

5. The device of claim 2 wherein the hollow extension is configured to reversibly receive a vial.

6. The device of claim 2 wherein the hollow extension comprises a base surface disposed distally relative to the first end of the piston, and wherein the hollow extension is configured to selectively retain a liquid.

7. The device of claim 2 wherein the piercing structure is disposed at least partially within the hollow extension.

8. The device of claim 7 wherein the piercing structure comprises a channel passing therethrough.

9. The device of claim 8 wherein the piercing structure has a tip, an external surface, and a base surface opposing the tip, and wherein the channel passes through the base surface and through the external surface at a position other than the tip.

10. The device of claim 8 wherein the channel is in fluid communication with the fluid passageway comprised by the piston.

11. The device of claim 8 wherein the piercing device is configured to puncture a septum associated with a vial and span the septum such that selective fluid communication is provided between the chamber and the vial through the fluid passageway and through the channel by way of the valve.

12. The device of claim 1, wherein the fluid passageway passes through the seal.

13. The device of claim 12 wherein the fluid passageway passes centrally through the seal.

14. The device of claim 1 wherein the stem comprises a first portion and a second portion, and wherein the valve is disposed at a junction between the first portion and the second portion.

15. The device of claim 1 wherein the valve is selected from the group consisting of a stopcock, a ball valve, a push-type valve, a slider valve, and a gate valve.

16. The device of claim 1 wherein the piston is longitudinally slideable relative to the chamber, wherein the valve is configured to be at least partially disposed within the chamber when the piston is slid into a forward-most position.

17. The device of claim 1 wherein the valve comprises an elastomeric material.

18. The device of claim 17 wherein the stem comprises a hard-plastic material.

19. A syringe device comprising:

a syringe body comprising a cylindrical housing and a chamber within the housing;

a piston insertable within the chamber and having a longitudinal axis, the piston comprising a first stem portion and a second stem portion, the first stem portion and second stem portions together forming a rotatable valve that is controlled by rotation of the second stem portion relative to the first stem portion;

a fluid passageway extending along the longitudinal axis through the stem, such that the rotatable valve controls fluid passage though the piston; and

a piston seal attached to the first stem portion and being independent of the rotatable valve.

20. The syringe device of claim 19 wherein the rotatable valve comprises at least one o-ring.