Syringe devices and methods for mixing and administering medication

• US 7,731,679 B2
• Filed: 05/21/2007
• Issued: 06/08/2010
• Est. Priority Date: 10/13/2004
• Status: Active Grant

• Current Assignee: Hyprotek, Inc.
• Original Assignee: Hyprotek, Inc.
• Inventors: Tennican, Patrick O., Phipps, L. Myles, Michaelsen, Russell A.
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): FLICK, JASON E
• Application Number:
  US11/751,418
• Publication Number:
  US 20070260176A1
• Time in Patent Office: 1,114 Days
• Field of Search: 604/88
• US Class Current: 604/88
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2062 with directional valves
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2086 for fluid filtration
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2005/3117 Means preventing contamination of the medicament compartment of a syringe
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 5/002 Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics needle protection, e.g. caps, A61M5/3202; for sharps A61B50/3001
• CPC Class Codes: A61M 5/204 connected to external reservoirs for multiple refilling
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing

Abstract

The invention includes a device having a chamber within a syringe. A fluid passageway extends through a syringe piston. A valve is associated with the passageway controlling fluid passage through the piston. The invention includes a piercing structure having a head segment and a body portion, with a channel through the body portion and through at least one surface of the head without passing through the tip. In another aspect the invention encompasses a method of preparing an agent for administration to an individual. A first component is provided within a syringe and a second component is provided within a vial. A closed valve is associated with a fluid passageway between the vial and the syringe barrel through a piston. Valve repositioning allows fluid passage and sliding of the piston joins the first and second components. Repeated sliding of the piston mixes the components to produce the medication agent.

Claims

1. A method of preparing a medication agent for administration to an individual, comprising:

providing a syringe device comprising a syringe barrel having a forward end that is capped and a piston disposed at an initial position relative to the syringe barrel, the piston having a first end within the syringe barrel, an opposing second end, and having a unitary fluid passageway passing longitudinally through the piston, through the first end and through the second end;

providing a first component of a medicant within the syringe barrel;

providing a second component of a medicant within a vial disposed within a vial housing associated with the second end of the piston;

providing a valve associated with the fluid passageway, the fluid passageway providing fluid communication between the vial and the syringe barrel, the valve being initially provided in a closed position blocking fluid passage through the passageway;

repositioning the valve to allow fluid passage between the vial and the syringe barrel;

after repositioning the valve, sliding the piston in a first direction to join the first component with the second component within the vial;

mixing the first and second components to produce the medication agent by repeated sliding of the piston in opposing directions; and

drawing the medication agent into the syringe barrel, the syringe device being administration-ready through the first end of the syringe without removal of the vial from the device.

2. The method of claim 1 further comprising:

providing a piercing structure within the vial housing; and

prior to the repositioning, utilizing the piercing structure to pierce a septum comprised by the vial, wherein the fluid passage between the vial and the syringe barrel comprises passage through the piercing structure.

3. The method of claim 1 further comprising closing the valve after drawing the medication agent into the syringe barrel.

4. The method of claim 1 wherein the valve is associated with the piston, wherein the valve is disposed external to the syringe barrel while the piston is in the initial position, and wherein the valve at least partially enters the barrel during the mixing.

5. The method of claim 1 wherein the piston comprises:

a seal disposed at a first end;

a second end opposing the first end; and

a stem portion between the first end and the second end, wherein the fluid passageway extends through the seal, through the stem and through the second end.

6. The method of claim 5 wherein the stem portion comprises a first segment, a second segment and a junction between the first and second segments, wherein the valve is disposed at the junction.

7. The method of claim 1 further comprising providing a piercing structure comprising:

a base portion having a first diameter;

a head segment having a widest portion and an opposing tip, having a beveled front surface and having a back surface that joins the front surface at opposing cutting edges;

a stem portion extending between the base portion and the head segment, the stem portion having a second diameter that is smaller than the first diameter and shorter than the widest portion of the head segment, wherein the fluid passageway passes through the piercing structure radially centrally through the base and stem portions and through the head segment at a position on the front surface where two bevels meet and other than at the tip.

8. The method of claim 1 wherein at least one of the first and second components is in liquid form.

9. The method of claim 1 wherein the first component is a liquid and wherein joining the first and second components comprises flowing the first component into the vial.

10. The method of claim 1 wherein the second component is a liquid and wherein joining the first and second components comprises flowing the second component into the syringe barrel.

11. The method of claim 1 wherein the medication agent is administration-ready upon drawing into the syringe barrel, and wherein administering the agent to an individual comprises ejecting the agent from the syringe barrel while the valve is in the closed position.

12. The method of claim 11 further comprising attaching a needle to the syringe, and wherein the administering comprises ejecting the agent through the needle.

13. The method of claim 12 wherein the needle is attached after drawing the agent into the syringe barrel.

14. A method of preparing a medicant comprising:

providing a mixing device comprising;

a needleless syringe having a first end having an extension with a male fitting and a piston inserted within a second end; and

an adaptor connected to a first end of the syringe, the adaptor comprising a first port, a second port consisting of a female fitting associated with the first end of the syringe, a third port associated with a vial, and a valve controlling fluid passage the ports; and

flowing a liquid into the adaptor through the first port and into the syringe through the second port.

15. The method of claim 14 wherein the vial contains a first component of a medicant, and further comprising mixing the liquid with the first component.

16. The method of claim 15 wherein the syringe contains a second component of the medicant, and wherein the liquid is mixed with the second component prior to mixing with the first component.