Techniques for positioning therapy delivery elements within a spinal cord or brain

• US 7,734,342 B2
• Filed: 01/31/2007
• Issued: 06/08/2010
• Est. Priority Date: 04/30/1998
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Schendel, Michael, Starkebaum, Warren, Gielen, Frans, Petersen, Daryle, Rise, Mark T., King, Gary W.
• Primary Examiner(s): Bockelman; Mark W
• Assistant Examiner(s): So; Elizabeth K
• Application Number:
  US11/669,758
• Publication Number:
  US 20070123954A1
• Time in Patent Office: 1,224 Days
• Field of Search: 607/2, 607/3, 607/115, 607/116, 607/117, 607/120, 607/122, 607/126, 607/129, 607/130, 607/51, 607/139, 600/377, 600/378, 623/23.49
• US Class Current: 607/3
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 2210/0693 Brain, cerebrum
• CPC Class Codes: A61M 2210/1003 Spinal column
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/0539 Anchoring of brain electrode systems, e.g. within burr hole
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/36071 Pain

Abstract

Apparatus and techniques to address problems associated with lead migration, patient movement or position, histological changes, neural plasticity or disease progression. Disclosed are techniques for implanting a lead having therapy delivery elements, such as electrodes or drug delivery ports, within a vertebral or cranial bone so as to maintain these elements in a fixed position relative to a desired treatment site. The therapy delivery elements may thereafter be adjusted in situ with a position control mechanism and/or a position controller to improve the desired treatment, such as electrical stimulation and/or drug infusion to a precise target. The therapy delivery elements may be positioned laterally in any direction relative to the targeted treatment site or toward or away from the targeted treatment site. A control system maybe provided for open- or closed-loop feedback control of the position of the therapy delivery elements as well as other aspects of the treatment therapy.

Claims

1. A medical device for providing therapy to a body comprising:

a lead having at least one therapy delivery element at a distal end of the lead;

a collar, the collar having outer threads and inner threads, wherein the collar is adapted to be screwed into the bone of the body using the outer threads; and

a threaded housing adapted so that at least a portion of the threaded housing is inserted into a channel defined by the collar, the treaded housing defining a proximal opening in a top portion of the threaded housing, a passageway through the threaded housing, and a distal opening, the proximal opening and passageway adapted to allow the therapy delivery element to be inserted therethrough and be positioned closer to the distal opening than the proximal opening.

2. The medical device according to claim 1, wherein the top portion of the threaded housing is adapted to be turned by a screwdriver-like device.

3. The medical device according to claim 1, further comprising an anchor adapted to attach to bone and to the lead, thereby fixing the position of the therapy delivery element at a target site of a patient.

4. The medical device according to claim 1, wherein the top portion of the threaded housing comprises a cavity adapted to be turned by a slotted screwdriver-like device.

5. The medical device according to claim 1, wherein the top portion of the threaded housing comprises a cavity adapted to be turned by a wrench-like device or percutaneous needle.

6. The medical device according to claim 1, wherein the therapy delivery element is an electrode.

7. The medical device according to claim 1, wherein the lead is a catheter and the therapy delivery element defines a drug infusion portion.

8. The medical device according to claim 1, wherein the collar comprises a ring to hold the threaded housing in position within the collar.

9. The medical device according to claim 1, wherein the collar comprises locking means to hold the threaded housing in position within the collar.

10. The medical device according to claim 1 comprising a plurality of leads and corresponding threaded housings and collars.

11. The medical device according to claim 10, further comprising a swivel mechanism to allow turning of a threaded housing but not a corresponding lead.

12. The medical device according to claim 10, in the further comprising a ball and socket to allow turning of a threaded housing but not the corresponding lead.

13. The medical device according to claim 2, wherein the threaded housing is a threaded screw and the collar comprises a burr hole ring.

14. A method for providing treatment therapy to targeted tissue comprising the steps of:

(a) implanting a therapy delivery device in a patient;

(b) implanting a collar into bone of a patient, the collar having outer and inner threads the other threads used to secure the collar into the bone of the patient;

(c) inserting a threaded housing into the collar, the threaded housing defining a proximal opening in a top portion of the housing, a passageway through the housing, and a distal opening;

(d) implanting a lead in the patient through the proximal opening and passageway of the threaded housing so that a therapy delivery element of the implanted lead lies closer to the distal opening than the proximal opening;

(e) coupling a proximal end of the lead to the implanted therapy delivery device; and

(f) operating the implanted therapy delivery device to provide treatment therapy to the targeted tissue via the therapy delivery element.

15. The method of claim 14, wherein the therapy delivery device comprises a signal generator and the therapy delivery element comprises an electrode.

16. The method as claimed in claim 14, wherein the therapy delivery device comprises a pump and the therapy delivery element comprises a drug infusion portion.

17. A medical device for providing therapy to a body comprising:

a plurality of leads, each lead having at least one therapy delivery element at a distal end of the lead;

a plurality of collars, the plurality of collars having outer and inner threads, the plurality of collars configured to be screwed into bone of the body using the outer threads;

a plurality of threaded housings configured such that at least a portion of the threaded housing is inserted into a channel defined by each of the plurality of collars, the plurality of threaded housings defining a proximal opening in a top portion of the threaded housings, a passageway through the threaded housings, and a distal opening, the proximal opening and passageway adapted to allow the therapy delivery element to be inserted therethrough and be positioned closer to the distal opening than the proximal opening; and

a swivel mechanism connected to each of the plurality of threaded housings, the swivel mechanism configured to allow turning of the threaded inner housing without moving the plurality of leads.

18. The medical device of claim 17, wherein the swivel mechanism comprises a ball and socket configuration.