Devices and methods for the repair of arteries

• US 7,736,377 B1
• Filed: 08/03/1999
• Issued: 06/15/2010
• Est. Priority Date: 08/03/1998
• Status: Expired due to Fees

• Current Assignee: Anson Medical Limited
• Original Assignee: Anson Medical Limited
• Inventors: Hopkinson, Brian Ridley, Yusuf, Syed Waquar, Anson, Anthony Walter
• Primary Examiner(s): Woo; Julian W
• Application Number:
  US09/762,223
• Time in Patent Office: 3,969 Days
• Field of Search: 606/219, 606/75, 606/154, 606/155, 606/156, 606/216, 606/151, 606/153, 606/213, 606/215, 606/188, 623/1.36, 24/679, 24/67.P, 243/50, 243/77, 243/80, 411457-460, 411/468, 411/515, 411/530
• US Class Current: 606/219
• CPC Class Codes: A61B 17/064 Surgical staples, i.e. penetrating the tissue
• CPC Class Codes: A61B 17/0644 penetrating the tissue, deformable to closed position
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/0641 having at least three legs as part of one single body
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2002/30092 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol

Abstract

A device for retaining a graft on an artery, comprising a first part for contacting the graft and a second part for contacting the artery when the device is pierced radially through the graft and the artery wall, the first and second parts being connected by a resilient member, wherein the resilient member biases the first and second parts towards each other into a retaining configuration such that in use the artery and the graft are retained together between the first and second parts of the device, and wherein the first and second parts are moveable into an open configuration in which they are further apart than in the retaining configuration to enable the device to be conveyed along an artery.

Claims

1. A fixator for retaining a graft on an artery comprising:

a. a plurality of first parts for contacting the graft when the device is pierced radially through the graft and the artery wall,

b. at least one second part for contacting the artery when the device is pierced radially through the graft and the artery wall, and

c. a resilient member connecting the first and second parts,

wherein the first and second parts each terminate in tips opposite the resilient member, with at least one of the tips being sharpened to enable the tip to pierce a graft and an artery, and wherein;

(1) the resilient member biases the first and second parts towards each other into a retaining configuration such that in use the artery and the graft are retained together between the first and second parts of the device, and

(2) the first and second parts are moveable into an open configuration in which they are;

(a) at least substantially disposed along a common axis with the resilient member, and

(b) further apart than in the retaining configuration to enable the device to be conveyed along an artery, and

(3) only the first and second parts extend from the resilient member, such that all structures extending from the resilient member move between the retaining and open configurations,

and wherein the resilient member has a cross-sectional area at least substantially equal to the greater of;

the sums of the cross-sectional areas non-sharpened portions of the first parts when the first parts are in their open configuration, and

ii. the sums of the cross-sectional areas non-sharpened portions of the second parts when the second parts are in their open configuration.

2. The fixator of claim 1 wherein in the retaining configuration at least one of the first and second parts forms an arcuate shape.

3. The fixator of claim 1 wherein at least a portion of both the first and second parts is sharpened to enable said parts to pierce a graft and an artery.

4. The fixator of claim 1 wherein the device is formed from one or more wires, the wires having lengths extending from the first parts to the second parts.

5. The fixator of claim 1 wherein the device is formed from a shape memory alloy.

6. The fixator of claim 1 wherein the device has a plurality of second parts.

7. The fixator of claim 6 wherein said plurality of parts are integral or welded together.

8. The fixator of claim 6 wherein the device has equal numbers of first and second parts.

9. The fixator of claim 8 which is formed of a plurality of wires, each wire comprising a first part, a resilient member and a second part, wherein the plurality of wires are linked together by a weld, a sheath, a bush, a crimp or by wire.

10. The fixator of claim 1 in combination with a graft, wherein the fixator extends through the graft with its first parts contacting the surface of the graft, and with the resilient member extending through the graft.

11. The fixator of claim 1 wherein the first parts, second parts, and resilient member are all at least substantially coaxial when the first and second parts are in their open configuration.

12. The fixator of claim 1 wherein the first parts are adjacently aligned in abutment with each other when the first and second parts are in their open configuration.

13. The fixator of claim 1 wherein:

a. the first parts are adjacently aligned in abutment with each other, and

a. the second parts are adjacently aligned in abutment with each other,

when the first and second parts are in their open configuration.

14. The fixator of claim 1 wherein the fixator, when in the retaining configuration, is shorter along a direction aligned along the common axis than when in the open configuration.

15. The fixator of claim 1 wherein at least one of the first and second parts is sharpened at a location most distant from the resilient member, as measured along a length extending from the resilient member along the first and second parts.

16. A kit comprising:

A. A fixator for retaining a graft on an artery, the fixator including;

a. a plurality of first parts for contacting the graft when the device is pierced radially through the graft and the artery wall,

b. at least one second part for contacting the artery when the device is pierced radially through the graft and the artery wall, and

c. a resilient member connecting the first and second parts,

wherein at least a portion of at least one of the first and second parts is sharpened to enable said part to pierce a graft and an artery, and wherein;

(1) the resilient member biases the first and second parts towards each other into a retaining configuration such that in use the artery and the graft are retained together between the first and second parts of the device, and

(2) the first and second parts are moveable into an open configuration in which they are;

(a) at least substantially disposed along a common axis with the resilient member, and

(b) further apart than in the retaining configuration to enable the device to be conveyed along an artery,

B. at least one of;

a. a device for supporting a catheter within an artery or arterial graft, the device including;

(1) a locating member for locating the device with respect to a catheter,

(2) a plurality of support members for supporting a catheter on the inner wall of the artery or graft,

(3) a resilient member connecting the locating member and the support members, wherein the resilient member is configured to bias the support members towards the artery wall,

(4) means for reducing the distance between the end of each support member distal to the locating member and the end of said support member proximate the locating member, thereby causing a central section of said support member to bow radially outward with respect to the locating member;

b. a device for dilating an artery when delivered translumenally to a locus of an artery by means of a catheter, the device including;

(1) a locating member for locating the device with respect to a catheter;

(2) a plurality of dilating members,

(3) a resilient member connecting the dilating members to the locating member and configured to bias the dilating member towards and into contact with the inner artery wall, whereby in use the resilient members cause the dilating members to apply outward pressure to the inner artery wall and dilate the artery,

(4) means for reducing the distance between the end of each dilating member distal to the locating member and the end of said dilating member proximate the locating member, thereby causing the central section of said dilating member to bow radially outward with respect to the locating member in order to apply increased outward pressure on the inner wall of the artery when the device is in use.

17. A fixator for retaining a graft on an artery consisting of elongated members, each elongated member extending between at least one first part and at least one second part terminating in tips, wherein the tip of at least one of the first and second parts is sharpened, wherein each elongated member is capable of:

a. an open configuration wherein;

(1) the first and second parts are distant and are at least substantially aligned along a common axis,

(2) the first parts are adjacently situated with their lengths in abutment,

(3) the second parts are adjacently situated with their lengths in abutment,

(4) the first parts and second parts of the elongated members are all at least substantially coaxial when the elongated members are in their open configuration,

(5) the fixator has an at least substantially uniform cross-sectional area as it extends from its first parts to its second parts; and

b. a retaining configuration wherein the first and second parts are closely spaced, and wherein each elongated member is biased towards the retaining configuration,

whereby the elongated members of the fixator may in the open configuration be inserted into the circumference of a graft-bearing artery to pierce the graft and artery, and may then be released to move to the retaining configuration, wherein the graft and artery are maintained between the first and second parts.

18. The fixator of claim 17 wherein each elongated member extends entirely between its first and second parts, whereby its first and second parts define its terminal ends.

19. The fixator of claim 17 wherein the fixator, when in the retaining configuration, is shorter along a direction aligned along the common axis than when in the open configuration.

20. A fixator for retaining a graft on an artery, the fixator comprising elongated members:

a. extending between first and second parts, at least one of the first and second parts being sharpened, and

b. being connected between their first and second parts, wherein each elongated member moves between;

(1) an open configuration wherein;

(a) the elongated member and its first and second parts are at least substantially oriented along a linear axis with its first and second parts distantly spaced, and

(b) the fixator has an at least substantially uniform cross-sectional area between the first and second parts and along the connection therebetween,

(2) a retaining configuration wherein the elongated member is bent so that its first and second parts are closely spaced,

and wherein;

i. only the first and second parts extend from the connection between the elongated members, and

ii. the elongated members, when in their open configurations, have their first parts adjacently situated in abutment and their second parts adjacently situated in abutment;

whereby the elongated members of the fixator may in the open configuration be inserted into the circumference of a graft-bearing artery to pierce the graft and artery, and may then be moved to the retaining configuration to situate the graft and artery between the first and second parts.

21. The fixator of claim 20 wherein each elongated member is normally biased into the retaining configuration.

22. The fixator of claim 20 wherein the first parts and second parts of the elongated members are all at least substantially coaxial when the elongated members are in their open configuration.

23. The fixator of claim 20 wherein the fixator, when in the retaining configuration, is shorter along a direction aligned along the linear axis than when in the open configuration.

24. The fixator of claim 20 which is formed of wires, each wire including:

a. one of the first parts, and

b. one of the second parts,

wherein the wires are connected between their first and second parts by a weld, a sheath, a bush, a crimp or by wire.

25. The fixator of claim 20 wherein at least one of the first and second parts is sharpened at a location most distant from the connection between the first and second parts, as measured along a length extending from the connection along the first and second parts.