Implantable device and method for the electrical treatment of cancer
First Claim
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1. A medical device for the treatment of abnormal tissue growth in a patient'"'"'s body comprising:
- a power source;
circuitry coupled to said power source;
at least one electrode operably coupled to said circuitry wherein said circuitry delivers direct current electrical therapy involving multiple voltages to said at least one electrode continuously for a period of time not less than 1 minute for the treatment of abnormal tissue growths;
a catheter operatively implanted into the patient'"'"'s body and into contact with the abnormal tissue growth for delivering a therapeutic agent to the abnormal tissue growth, said catheter having a central lumen open at a proximal end and a distal end, the distal end positioned at or near the abnormal tissue growth and the proximal end positioned external to the body and away from the abnormal tissue growth;
a porous drug absorbing material coupled to the distal end of the catheter, said porous material in contact with a surface portion of the abnormal tissue growth; and
an electrode array comprising a plurality of electrodes coupled to the circuitry and configured to steer the therapeutic agent along a predetermined path from the catheter distal end, said array comprising a plurality of point electrodes configured on the porous material.
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Abstract
An implantable electrical method and apparatus for the treatment of cancer tumors based on the usage of various levels of electrical fields and current to assist in specific ways to reduce tumor size. The appropriate voltage, currents, and time duration as well as the usage of adjunctive pharmacological therapy are taught.
89 Citations
37 Claims
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1. A medical device for the treatment of abnormal tissue growth in a patient'"'"'s body comprising:
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a power source; circuitry coupled to said power source; at least one electrode operably coupled to said circuitry wherein said circuitry delivers direct current electrical therapy involving multiple voltages to said at least one electrode continuously for a period of time not less than 1 minute for the treatment of abnormal tissue growths; a catheter operatively implanted into the patient'"'"'s body and into contact with the abnormal tissue growth for delivering a therapeutic agent to the abnormal tissue growth, said catheter having a central lumen open at a proximal end and a distal end, the distal end positioned at or near the abnormal tissue growth and the proximal end positioned external to the body and away from the abnormal tissue growth; a porous drug absorbing material coupled to the distal end of the catheter, said porous material in contact with a surface portion of the abnormal tissue growth; and an electrode array comprising a plurality of electrodes coupled to the circuitry and configured to steer the therapeutic agent along a predetermined path from the catheter distal end, said array comprising a plurality of point electrodes configured on the porous material. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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33. A medical device for the treatment of abnormal tissue growth in a patient'"'"'s body comprising:
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a power source; circuitry coupled to said power source; at least one electrode operably coupled to said circuitry wherein said circuitry delivers direct current electrical therapy involving multiple voltages to said at least one electrode continuously for a period of time not less than 1 minute for the treatment of abnormal tissue growths; a catheter operatively implanted into the patient'"'"'s body and into contact with the abnormal tissue growth for delivering a therapeutic agent to the abnormal tissue growth, said catheter having a central lumen open at a proximal end and a distal end, the distal end positioned at or near the abnormal tissue growth and the proximal end positioned external to the body and away from the abnormal tissue growth; a porous drug absorbing material coupled to the distal end of the catheter, said porous material in contact with a surface portion of the abnormal tissue growth; and an electrode array comprising a plurality of electrodes coupled to the circuitry and configured to steer the therapeutic agent along a predetermined path from the catheter distal end; and at least two concentric electrodes arranged within the porous material. - View Dependent Claims (34, 35, 36, 37)
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Specification