Implanted air passage sensors

• US 7,744,542 B2
• Filed: 04/20/2006
• Issued: 06/29/2010
• Est. Priority Date: 04/20/2006
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Piaget, Thomas, Stahmann, Jeffrey E., Hatlestad, John D., Huelskamp, Paul
• Primary Examiner(s): Mallari; Patricia C
• Assistant Examiner(s): D'ANGELO, MICHAEL J
• Application Number:
  US11/379,396
• Publication Number:
  US 20070249950A1
• Time in Patent Office: 1,531 Days
• Field of Search: 600/529, 600/538, 600/537, 600/309, 600/341, 600/300, 600/311, 600/489, 600/301, 600/486, 607/20, 607/42
• US Class Current: 600/529
• CPC Class Codes: A61B 2560/0242 adapted to measure environmental factors, e.g. temperature, pollution
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/036 by means introduced into body tracts A61B5/032 and A61B5/035 take precedence
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/0833 Measuring rate of oxygen consumption
• CPC Class Codes: A61B 5/0836 Measuring rate of CO2 production
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/68 Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
• CPC Class Codes: A61B 7/003 Detecting lung or respiration noise

Abstract

A physiological sensor is located within the airway of the subject'"'"'s body, such as for measuring barometric pressure and communicating this value to a blood pressure or other monitoring device, which can derive gauge pressure using the barometric pressure and a measured absolute pressure within the body. The physiological sensor may also detect one or more other physiological parameters such as air flow, sound, or a chemical property. It may be anchored within the airway with the ability to communicate wirelessly to one or more other medical devices, such as an implanted cardiac function management device. Methods of use are also described.

Claims

1. A system comprising:

an implantable medical device;

a first sensor module separate from and unattached to the implantable medical device, at least a portion of which is adapted to reside within an airway of a subject'"'"'s body, wherein the first sensor module comprises;

a first detector configured to detect an external air pressure;

a communication module, coupled to the first detector, the communication module configured to transmit information about the external air pressure to the implantable medical device; and

an energy storage device, coupled to at least one of the first detector and the communication module; and

an anchor, attached to the first sensor module, the anchor configured to fixate at least a portion of the first sensor module within the airway; and

an absolute physiological pressure sensor module, at least a portion of which is adapted to reside within a circulatory system of the body, wherein the absolute physiological pressure sensor module comprises;

an absolute physiological pressure detector configured to detect an absolute pressure;

a communication module, coupled to the absolute physiological pressure detector, configured to transmit information about the absolute pressure to the implantable medical device;

an energy storage device, coupled to at least one of the absolute physiological pressure detector and communication module; and

an anchor configured to fixate at least a portion of the absolute physiological pressure detector within the circulatory system; and

wherein the implantable medical device includes a communication module configured to receive information about the external air pressure from the communication module of the first sensor module and information about the absolute pressure from the communication module of the absolute physiological pressure sensor module, the implantable medical device including a processor configured to derive a gauge pressure using the external air pressure and the absolute pressure.

2. The system of claim 1, including a processor to receive information about the external air pressure and the absolute pressure and to provide a responsive indication of hypertension.

3. The system of claim 1,

wherein the communication module of the implantable medical device is configured to wirelessly receive information about the external air pressure from the communication module of the first sensor module.

4. The system of claim 3,

wherein the implantable medical device is separate from and unattached to the absolute physiological pressure sensor module.

5. The system of claim 1, in which the anchor includes an expandable stent-like structure configured to maintain airway patency.

6. The system of claim 1, in which the anchor includes an antenna.

7. The system of claim 1, in which the communication module of the first sensor module comprises an inductor for communication.

8. The system of claim 1, in which the communication module of the first sensor module is configured to transmit information wirelessly, and comprises one or more of an ultrasonic transmitter, an inductive transmitter, and a radio frequency (RF) transmitter.

9. A method comprising:

detecting a barometric pressure from an at least partially implantable first sensor at a first location within an airway of a subject'"'"'s body;

detecting an absolute pressure from an at least partially implantable second sensor at a second location within a circulatory system of the subject'"'"'s body;

communicating information about the barometric pressure and information about the absolute pressure to an implantable medical device at a third location within the subject'"'"'s body;

deriving information about a gauge pressure from the information about the barometric pressure and the information about the absolute pressure.

10. The method of claim 9, in which the communicating information comprises wirelessly communicating the information to the implantable medical device, wherein the implantable medical device is separate from and unattached to at least one of the first and second sensors.

11. The method of claim 9, comprising delivering therapy using the information about the gauge pressure as a control.

12. The method of claim 9, comprising trending over time the information about the gauge pressure.

13. The method of claim 9, in which the communicating includes one or more of acoustic communication, radio frequency communication, inductive communication, and communication using the body as an electrical signal conductor.

14. The method of claim 9, comprising anchoring at least a portion of a first sensor within the airway.

15. The method of claim 14, in which the anchoring comprises expanding an anchor.

16. The method of claim 15, comprising receiving or transmitting a communication signal using the anchor as an antenna.

17. A system comprising:

an implantable medical device, including;

a first sensor interface circuit,

a second sensor interface circuit, and

a biocompatible housing configured to include at least a portion of the first and second interface circuits;

a first sensor module, at least a portion of which is adapted to reside within an airway of a subject'"'"'s body, separate and remote from and unattached to the implantable medical device, wherein the first sensor module comprises;

a first detector configured to detect external barometric pressure from within the airway; and

a first communication module, coupled to the first detector, configured to transmit information about the barometric pressure to the first sensor interface circuit; and

an anchor, attached to the first sensor module, the anchor configured to fixate at least a portion of the first sensor module within the airway; and

a second sensor module, at least a portion of which is adapted to reside within a circulatory system of the body, separate and remote from and unattached to the imp1antable medical device and the first sensor module, wherein the second sensor module comprises;

a second detector configured to detect an absolute physiological pressure; and

a second communication module, coupled to the second detector, configured to transmit information about the absolute pressure to the second sensor interface circuit;

wherein the implantable medical device includes a processor configured to derive a gauge pressure using information about the absolute pressure received from the second detector and using barometric pressure information received from the first detector.

18. The system of claim 17, wherein the first sensor module comprises:

an energy storage device, coupled to at least the first detector and the first communication module; and

an anchor, configured to fixate at least a portion of the first detector within the airway.

19. The system of claim 18, wherein the second sensor module comprises:

an anchor configured to fixate at least a portion of the second detector within the circulatory system.