Fluorophore embedded/incorporating/bridged periodic mesoporous organosilicas as recognition elements for optical sensors
First Claim
Patent Images
1. A method for detecting a target molecule in a sample comprising:
- providing a periodic mesoporous organosilica incorporating an optically active molecule, wherein said periodic mesoporous organosilica is configured to orient a target molecule with respect to said optically active molecule;
providing a sample containing a target molecule;
exposing said periodic mesoporous organosilica to said sample, wherein said target molecule is adsorbed into said periodic mesoporous organosilica;
providing a light source; and
exposing said periodic mesoporous organosilica to said light source, wherein said optically active molecule undergoes a change that detects the presence of said target molecule.
1 Assignment
0 Petitions
Accused Products
Abstract
Periodic mesoporous organosilicas (PMO) which incorporate an optically active molecule into the material for use as an optical indicator of target binding. This material combines the stability, selectivity, and high density of binding sites characteristic of the PMO with the sensitivity and selectivity of the optically active molecule. The material undergoes a change when exposed to a sample containing a target molecule. The change can be observed by visual inspection or through the use of fluorescence spectra.
-
Citations
18 Claims
-
1. A method for detecting a target molecule in a sample comprising:
-
providing a periodic mesoporous organosilica incorporating an optically active molecule, wherein said periodic mesoporous organosilica is configured to orient a target molecule with respect to said optically active molecule; providing a sample containing a target molecule; exposing said periodic mesoporous organosilica to said sample, wherein said target molecule is adsorbed into said periodic mesoporous organosilica; providing a light source; and exposing said periodic mesoporous organosilica to said light source, wherein said optically active molecule undergoes a change that detects the presence of said target molecule. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
-
-
10. A system for detecting a target molecule in a sample comprising:
-
a periodic mesoporous organosilica incorporating an optically active molecule, said optically active molecule, wherein said periodic mesoporous organosilica is configured to orient a target molecule with respect to said optically active molecule; means for exposing said periodic mesoporous organosilica to a sample containing a target molecule, wherein said optically active molecule undergoes a change in the presence of said target molecule; and a means for visualizing said change in said optically active molecule, said change indicating the presence of said target molecule in said sample. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18)
-
Specification