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Bilirubin sensor

  • US 7,749,766 B2
  • Filed: 01/12/2007
  • Issued: 07/06/2010
  • Est. Priority Date: 01/12/2007
  • Status: Active Grant
First Claim
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1. A bilirubin sensor comprising:

  • a working electrode with a first chemical matrix disposed thereon, the first chemical matrix containing a binder, wherein the first chemical matrix is capable of oxidizing all oxidizable species in a fluid sample;

    a substrate electrode with a second chemical matrix disposed thereon, the second chemical matrix containing a binder and a chemical agent that consumes bilirubin, wherein the second chemical matrix is capable of oxidizing all oxidizable species in the fluid sample except bilirubin;

    a reference electrode;

    a sample chamber containing the working electrode, the substrate electrode and the reference electrode;

    means for applying a potential between the reference electrode and the working electrode to obtain a first current;

    means for applying a potential between the reference electrode and the substrate electrode to obtain a second current;

    means for correlating the first current to a concentration of all oxidizable species in the fluid sample and for correlating the second current to a concentration of all oxidizable species in the fluid sample except bilirubin;

    means for subtracting the second current from the first current to obtain a current difference;

    and means for correlating the current difference to a concentration of bilirubin in the fluid sample.

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