Disposable medicine dispensing device

• US 7,753,879 B2
• Filed: 01/28/2005
• Issued: 07/13/2010
• Est. Priority Date: 01/29/2004
• Status: Active Grant

• Current Assignee: Insulet Corporation, M2 Medical Group Holdings, Inc.
• Original Assignee: M2 Group Holdings Inc (Abbott Laboratories)
• Inventors: Mernoe, Morten
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): MEDWAY, SCOTT J
• Application Number:
  US10/587,911
• Publication Number:
  US 20070276329A1
• Time in Patent Office: 1,992 Days
• Field of Search: 604/145, 604/155, 604/218, 604/223, 604/228, 604/232, 604/235, 604/131
• US Class Current: 604/131
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 2005/1426 with means for preventing access to the needle after use
• CPC Class Codes: A61M 2005/14533 cam actuated
• CPC Class Codes: A61M 2005/31518 designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
• CPC Class Codes: A61M 2205/0222 Materials for reducing friction
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1454 spring-actuated, e.g. by a clockwork
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: B05C 17/0113 the piston rod being flexible or articulated B05C17/0109 takes precedence

Abstract

A combination of a disposable, wearable, self-contained medicine dispensing device, a cylindrical medicine container 52 incorporating a piston and having an open distal end and a proximal end closed by a closure body 54 made of a material, preferably silicone, that can be perforated by a needle, and a catheter device 16 having adhesive means 26 for attaching the catheter device to the skin of a user of the combination, the dispensing device comprising a housing 34, 36 having a compartment for receiving the container and further a not shown piston rod for displacing the piston towards the closed proximal end and actuating means for displacing the piston rod, the catheter device comprising a sealing ring 56′for receiving the closure body, and the dispensing device and the catheter device comprising co-operating attachment means for attaching the dispensing device to the catheter device with the container received in the compartment with the piston rod abutting the piston and the closure body received in the sealing ring.

Claims

1. A disposable, wearable medicine dispensing device comprising

a housing;

means for attaching said housing to the skin of a user of said device,

a medicine container disposed in the housing;

a flexible piston rod having an outer thread pattern on at least a portion thereof, wherein the piston rod moves from a flexed configuration in the housing toward a forward longitudinal direction to force medicine from the medicine container;

a ratchet wheel having an inner thread pattern on a central aperture to mate with the outer thread pattern of the flexible piston rod such that rotation of said ratchet wheel in a forward rotational direction displaces the flexible piston rod in the forward longitudinal direction;

a pivotable body disposed in the housing and adjustable between a forward position and a reset position, wherein adjustment of the pivotable body from the reset position to the forward position causes the ratchet wheel to rotate in said forward rotational direction;

a spring device to bias said pivotable body toward the forward position; and

an actuation system to controllably adjust the pivotable body toward the reset position, the actuation system comprising;

a thread member coupled to the pivotable body, and

a battery powered actuator coupled to the thread member so as to apply a tension force to the thread and thereby adjust the pivotable body.

2. The dispensing device of claim 1, further comprising a pawl member disposed on a pivotable body.

3. The dispensing device of claim 1, wherein the flexible piston rod comprises rod segments hinged together, the outer thread pattern being on at least a portion of the rod segments.

4. The dispensing device of claim 3, wherein rod segments are connected by hinges that comprise integrally formed, bendable material.

5. The dispensing device of claim 4, wherein the bendable material comprises a material selected from the group consisting of Nylon or POM (polyoxymethylene).

6. The dispensing device of claim 3, wherein the outer thread pattern is a discontinuous thread pattern.

7. The dispensing device of claim 1, wherein the battery powered actuator is a solenoid.

8. The dispensing device of claim 7, wherein the solenoid actuates in a linear motion to apply the tension force to the thread member.

9. A disposable, wearable medicine dispensing device, comprising:

a wearable pump housing;

an adhesive layer coupled to the housing so as to affix said housing to skin of a user,

a medicine container disposed in the housing;

a flexible piston rod having an outer thread pattern on at least a portion thereof, wherein the piston rod moves from a flexed configuration in the housing toward a forward longitudinal direction relative to the medicine container to force medicine from the medicine container;

a ratchet wheel having an inner thread pattern on a central aperture to mate with the outer thread pattern of the flexible piston rod such that rotation of said ratchet wheel in a forward rotational direction displaces the flexible piston rod in the forward longitudinal direction;

a pivotable body disposed in the housing and pivotable between a forward position and a reset position, wherein adjustment of the pivotable body from the reset position to the forward position causes the ratchet wheel to rotate in said forward rotational direction;

a spring device to bias said pivotable body toward the forward position; and

an actuation system to controllably adjust the pivotable body toward the reset position, the actuation system comprising;

a thread member coupled to the pivotable body, and

a battery-powered mechanical actuator to move an end portion of the thread member so as to apply a tension force to the thread member and thereby adjust the pivotable body.

10. The device of claim 9, wherein the wearable pump housing is wearable on a user'"'"'s body and dispenses insulin to the user via a catheter tube while a handheld controller device having a user-interface buttons and a display communicates with the disposable dispensing device.

11. The device of claim 10, wherein the handheld controller device is connectable to a computer for transmission of data.

12. The device of claim 10, wherein the handheld controller device receives user input indicative of glucose level measurement results.

13. The device of claim 12, wherein the disposable dispensing device dispenses insulin to the user at a new dosage rate in response to the user input indicative of glucose level measurement results.

14. The dispensing device of claim 9, wherein the flexible piston rod comprises rod segments hinged together, the outer thread pattern being on at least a portion of the rod segments.

15. The dispensing device of claim 14, wherein the outer thread pattern is a discontinuous thread pattern.

16. The dispensing device of claim 9, wherein the battery-powered mechanical actuator is a solenoid.

17. A disposable, wearable medicine dispensing device, comprising:

a wearable pump housing;

a medicine container disposed in the housing;

a flexible piston rod having an outer thread pattern on at least a portion thereof, wherein the piston rod moves from a flexed configuration in the housing toward a forward longitudinal direction relative to the medicine container to force medicine from the medicine container;

a ratchet wheel having an inner thread pattern on a central aperture to mate with the outer thread pattern of the flexible piston rod such that rotation of said ratchet wheel in a forward rotational direction displaces the flexible piston rod in the forward longitudinal direction;

a pivotable body disposed in the housing and pivotable between a forward position and a reset position, wherein adjustment of the pivotable body from the reset position to the forward position causes the ratchet wheel to rotate in said forward rotational direction;

a spring device to bias said pivotable body toward the forward position; and

an actuation system to controllably adjust the pivotable body toward the reset position, the actuation system comprising;

a thread member coupled to the pivotable body, and

a battery-powered mechanical actuator to move an end portion of the thread member so as to apply a tension force to the thread member and thereby adjust the pivotable body.

18. The device of claim 17, wherein the wearable pump housing is wearable on a user'"'"'s body and dispenses insulin while a handheld controller device having a user-interface buttons and a display communicates with the disposable dispensing device.

19. The device of claim 18, wherein the handheld controller device receives user input indicative of glucose level measurement results.

20. The device of claim 19, wherein the disposable dispensing device dispenses insulin to the user at a new dosage rate in response to the user input indicative of glucose level measurement results.