Syringe devices and methods for mixing and administering medication

• US 7,753,891 B2
• Filed: 05/21/2007
• Issued: 07/13/2010
• Est. Priority Date: 10/13/2004
• Status: Active Grant

• Current Assignee: Hyprotek, Inc.
• Original Assignee: Hyprotek, Inc.
• Inventors: Tennican, Patrick O., Phipps, L. Myles, Michaelsen, Russell A.
• Primary Examiner(s): Sirmons; Kevin C
• Assistant Examiner(s): Anderson; Michael J
• Application Number:
  US11/751,434
• Publication Number:
  US 20070255226A1
• Time in Patent Office: 1,149 Days
• Field of Search: 604/205, 604/6.12, 604/88, 604/89, 604/411, 604/363, 604/82, 604/167.03, 604/246, 604/44, 604/272, 604/274
• US Class Current: 604/205
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2062 with directional valves
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2086 for fluid filtration
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2005/3117 Means preventing contamination of the medicament compartment of a syringe
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 5/002 Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics needle protection, e.g. caps, A61M5/3202; for sharps A61B50/3001
• CPC Class Codes: A61M 5/204 connected to external reservoirs for multiple refilling
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing

Abstract

The invention includes a device having a chamber within a syringe. A fluid passageway extends through a syringe piston. A valve is associated with the passageway controlling fluid passage through the piston. The invention includes a piercing structure having a head segment and a body portion, with a channel through the body portion and through at least one surface of the head without passing through the tip. In another aspect the invention encompasses a method of preparing an agent for administration to an individual. A first component is provided within a syringe and a second component is provided within a vial. A closed valve is associated with a fluid passageway between the vial and the syringe barrel through a piston. Valve repositioning allows fluid passage and sliding of the piston joins the first and second components. Repeated sliding of the piston mixes the components to produce the medication agent.

Claims

1. A device comprising:

a housing around a chamber;

a piston having a first end, a second end, and a fluid passageway from the first end to the second end, the piston being insertable into the chamber;

a valve associated with the fluid passageway such that flow through the fluid passageway is selectively regulated by the valve, the valve being disposed between the first and second ends of the piston at a position other than at the first or second end; and

a piercing structure proximate the second end of the piston, the piercing structure comprising;

a base portion having a first diameter;

a head segment comprising a tip, the head segment having a beveled front surface comprising first and second solid bevel faces, and a back surface that joins the front surface at cutting edges; and

a tube segment extending between the base portion and the head segment, the tube portion having a second diameter that is smaller than the first diameter and being more narrow than a widest position across the head segment, the piercing structure having an opening extending radially centrally through the base and a single opening extending through the front surface of the head segment at a point other than the tip at a position where the first and second solid bevel faces meet, the opening being in fluid communication with the fluid passageway.

2. The device of claim 1 wherein the piston is insertable into the chamber through a first end of the housing and wherein the housing is configured to receive a needle at an opposing second end.

3. The device of claim 1 wherein the piston comprises a seal disposed at the first end and wherein the passageway passes through the seal.

4. The device of claim 1 wherein the piston comprises a stem having a first part and a second part, and wherein the valve is disposed at a junction between the first and second parts.

5. The device of claim 1 wherein the piston has a piston length between the first and second ends, wherein the passageway has a minimum diameter along the piston length, and wherein a ratio of the piston length to the minimum diameter is greater than or equal to about 10:

1.

6. The device of claim 1 further comprising a container integral with the piston, wherein the container is in selective fluid communication with the chamber through the fluid passageway.

7. The device of claim 1 further comprising:

a hollow extension integral with the second end of the piston; and

wherein the piercing structure is disposed within the hollow extension, wherein the hollow extension is configured to receive a vial comprising a septum, and wherein the septum is able to be pierced by the piercing structure upon at least partial insertion of the vial within the housing.

8. The device of claim 7 wherein the opening comprised by the piercing structure allows fluid communication between the fluid passageway and an internal region of the vial upon piercing the septum.