Natriuretic polypeptides
First Claim
Patent Images
1. A polypeptide less than 36 amino acid residues in length, wherein said polypeptide comprises, in an order from amino terminus to carboxy terminus:
- (a) the sequence set forth in SEQ ID NO;
1 or the sequence set forth in SEQ ID NO;
1 with no more than one addition, subtraction, or substitution,(b) the sequence set forth in SEQ ID NO;
2 or the sequence set forth in SEQ ID NO;
2 with no more than two additions, subtractions, or substitutions, and(c) the sequence set forth in SEQ ID NO;
3 or the sequence set forth in SEQ ID NO;
3 with no more than one addition, subtraction, or substitution.
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Accused Products
Abstract
This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing natriuretic activities within a mammal.
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Citations
19 Claims
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1. A polypeptide less than 36 amino acid residues in length, wherein said polypeptide comprises, in an order from amino terminus to carboxy terminus:
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(a) the sequence set forth in SEQ ID NO;
1 or the sequence set forth in SEQ ID NO;
1 with no more than one addition, subtraction, or substitution,(b) the sequence set forth in SEQ ID NO;
2 or the sequence set forth in SEQ ID NO;
2 with no more than two additions, subtractions, or substitutions, and(c) the sequence set forth in SEQ ID NO;
3 or the sequence set forth in SEQ ID NO;
3 with no more than one addition, subtraction, or substitution. - View Dependent Claims (2, 3, 4, 5, 6, 8, 9, 10, 11, 16, 17, 18, 19)
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- 7. A polypeptide comprising the sequence set forth in SEQ ID NO:
Specification