Methods and systems for detecting the presence of T-wave alternans
First Claim
1. In an implantable system, a method for detecting T-wave alternans, comprising:
- (a) detecting at least one intrinsic premature contraction of the ventricles;
(b) measuring at least one metric of T-waves in a specified number of beats that follow each detected intrinsic premature contraction of the ventricles; and
(c) determining if the detected intrinsic premature contraction of the ventricles is immediately preceded by at least a specified number of non-premature contractions of the ventricles and further determining, based on the measured T-wave metrics, whether T-wave alternans are present wherein, if the detected intrinsic premature contraction is not immediately preceded by at least the specified number of non-premature contractions then the T-wave metrics following the detected intrinsic premature contraction are either not measured or not used in determining if T-wave alternans are present.
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Abstract
Embodiments of the present invention relate to implantable systems, and method for use therein, that can detect T-wave alternans. In accordance with specific embodiments of the present invention, intrinsic premature contractions of the ventricles are detected, and at least one metric of T-waves is measured in a specified number of beats that follow each detected intrinsic premature contraction of the ventricles. A determination of whether T-wave alternans are present is made based on the measured T-wave metrics. In alternative embodiments, rather than waiting for intrinsic premature contractions of the ventricles, premature contractions of the ventricles are caused on demand by inducing premature atrial contractions. In still other embodiments, a patient'"'"'s vagus nerve is stimulated to simulate premature contractions of the ventricles. This abstract is not intended to be a complete description of, or limit the scope of, the invention.
55 Citations
15 Claims
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1. In an implantable system, a method for detecting T-wave alternans, comprising:
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(a) detecting at least one intrinsic premature contraction of the ventricles; (b) measuring at least one metric of T-waves in a specified number of beats that follow each detected intrinsic premature contraction of the ventricles; and (c) determining if the detected intrinsic premature contraction of the ventricles is immediately preceded by at least a specified number of non-premature contractions of the ventricles and further determining, based on the measured T-wave metrics, whether T-wave alternans are present wherein, if the detected intrinsic premature contraction is not immediately preceded by at least the specified number of non-premature contractions then the T-wave metrics following the detected intrinsic premature contraction are either not measured or not used in determining if T-wave alternans are present. - View Dependent Claims (2, 3, 4, 5)
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6. An implantable system for detecting T-wave alternans (TWA), comprising:
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means for measuring at least one metric of T-waves in a specified number of beats that follow each detected intrinsic premature contraction of the ventricles; a TWA detector means to determine, based on the measured T-wave metrics, and based on the number of non-premature contractions of the ventricles that immediately precede the detected intrinsic premature contraction, whether T-wave alternans are present wherein, if the detected intrinsic premature contraction is not immediately preceded by at least the specified number of non-premature contractions then the T-wave metrics following the detected intrinsic premature contraction are either not measured or not used in determining if T-wave alternans are present. - View Dependent Claims (7, 8, 9, 10)
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11. In an implantable system, a method comprising:
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(a) detecting intrinsic premature contractions of the ventricles; (b) measuring one or more metrics of T-waves in a specified number of beats that follow each premature contraction of the ventricles detected at step (a); (c) determining for each detected intrinsic premature contraction of the ventricles if it is immediately preceded by at least a specified number of non-premature contractions of the ventricles and further determining, based on the measured T-wave metrics, magnitudes of alternation, wherein, for each intrinsic premature contraction detected in step (a) if the detected intrinsic premature contraction is not immediately preceded by at least the specified number of non-premature contractions then the T-wave metrics following the detected intrinsic premature contraction are either not measured or not used in determining magnitudes of alteration; (d) comparing the magnitudes of alternation to one or more thresholds; and (e) triggering one or more responses based on results of the comparisons performed at step (d). - View Dependent Claims (12, 13, 14, 15)
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Specification