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Hemofiltration systems, methods and devices for treatment of chronic and acute diseases

  • US 7,758,533 B2
  • Filed: 11/05/2007
  • Issued: 07/20/2010
  • Est. Priority Date: 03/24/2000
  • Status: Expired due to Fees
First Claim
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1. A hemofiltration system operable to treat an Inflammatory Mediator Related Disease in a mammal comprising:

  • a hemofilter having a molecular weight exclusion limit equal to or greater than approximately 69,000 Daltons, operable to remove an ultrafiltrate from a blood stream extracted from the mammal and to create a filtered blood stream in a return flow path to the mammal and an ultrafiltrate stream;

    at least one therapeutic agent used in association with the hemofilter to treat the Inflammatory Mediator Related Disease, the therapeutic agent deliverable via the return flow path to the mammal; and

    an adsorptive device containing at least one adsorbent material operable to receive the ultrafiltrate stream from the hemofilter and to remove an inflammatory mediator therefrom to create a post adsorption ultrafiltrate routable to at least one of the return flow path and waste.

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