Medical device including cylindrical micelles
First Claim
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1. A stent comprising:
- an expandable framework having a first end, a second end, an outer diameter defining an outer surface, and an inner diameter defining an inner surface forming a lumen, the expandable framework including a plurality of interconnected segments; and
a plurality of cylindrical micelles incorporated with the expandable framework, the cylindrical micelles formed of multi-block amphiphilic copolymers self-assembling in a solution such that the cylindrical micelles have an outer shell region including a first polymer block of the multi-block amphiphilic copolymer surrounding a core region including a second polymer block of the multi-block amphiphilic copolymer, wherein the first polymer block is more soluble in the solution than the second polymer block.
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Abstract
An endovascular stent comprising an expandable framework including a plurality of interconnected segments, and a plurality of entangled cylindrical micelles disposed on the expandable framework. Each of the plurality of cylindrical micelles may be loaded with a therapeutic agent.
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Citations
20 Claims
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1. A stent comprising:
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an expandable framework having a first end, a second end, an outer diameter defining an outer surface, and an inner diameter defining an inner surface forming a lumen, the expandable framework including a plurality of interconnected segments; and a plurality of cylindrical micelles incorporated with the expandable framework, the cylindrical micelles formed of multi-block amphiphilic copolymers self-assembling in a solution such that the cylindrical micelles have an outer shell region including a first polymer block of the multi-block amphiphilic copolymer surrounding a core region including a second polymer block of the multi-block amphiphilic copolymer, wherein the first polymer block is more soluble in the solution than the second polymer block. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification