System and method for generating a 2D image from a tomosynthesis data set

• US 7,760,924 B2
• Filed: 11/21/2008
• Issued: 07/20/2010
• Est. Priority Date: 11/27/2002
• Status: Expired due to Term

• Current Assignee: Hologic Incorporated
• Original Assignee: Hologic Incorporated
• Inventors: Stein, Jay, Smith, Andrew, Ruth, Chris
• Primary Examiner(s): Ahmed; Samir A.
• Assistant Examiner(s): Bayat; Ali
• Application Number:
  US12/276,006
• Publication Number:
  US 20090123052A1
• Time in Patent Office: 606 Days
• Field of Search: 382128-134, 382/154, 356/12, 348419-427
• US Class Current: 382/128
• CPC Class Codes: A61B 6/025 Tomosynthesis
• CPC Class Codes: A61B 6/502 for diagnosis of breast, i.e. mammography
• CPC Class Codes: G06T 11/006 Inverse problem, transformation from projection-space into object-space, e.g. transform methods, back-projection, algebraic methods
• CPC Class Codes: G06T 15/08 Volume rendering
• CPC Class Codes: G06T 2207/30068 Mammography; Breast
• CPC Class Codes: G06T 2210/41 Medical

Abstract

A 2D mammogram image is synthesized from at least one of tomosynthesis projection images and/or the tomosynthesis reconstructed image data. In a simplest form, the mammogram may be synthesized by selecting one of the tomosynthesis projection images for display as a synthesized mammogram. Other methods of synthesizing a mammogram include re-projecting and filtering projection data and/or reconstructed data. The synthesized mammogram is advantageously displayed together with at least a portion of the reconstructed data to aid in review of the reconstructed data. The present invention thus provides a familiar image which may be used to facilitate review of a tomosynthesis data set.

Claims

1. A method for use in a computer system comprising one or more processors performing the steps of:

obtaining a plurality of x-ray tomosynthesis projection images of a patient'"'"'s breast;

generating a three dimensional reconstruction of the patient'"'"'s breast using the x-ray projection images;

synthesizing a two-dimensional mammogram using at least a subset of the plurality of x-ray tomosynthesis projection images, including re-projecting at least a portion of the three dimensional reconstruction onto a two-dimensional image; and

displaying the synthesized mammogram on a display device.

2. The method of claim 1 wherein the step of synthesizing the two dimensional mammogram includes the step of selecting one of the x-ray tomosynthesis projection images for use as the two-dimensional mammogram.

3. The method of claim 1 wherein the step of synthesizing the two dimensional mammogram includes the step of performing at least one of filtering and combining of a subset of the plurality of x-ray tomosynthesis images.

4. The method of claim 1 including the step of displaying the synthesized mammogram together with at least a portion of the three-dimensional reconstruction.

5. The method of claim 1 wherein the synthesized mammogram and at least a portion of the three-dimensional reconstruction are displayed overlaid to enable toggling between the synthesized mammogram and the portion of the three-dimensional reconstruction.

6. The method of claim 1 including the step of providing a user interface for controlling the display of at least one of a portion of the three dimensional reconstruction, at least one of the x-ray projection images and the mammogram.

7. The method of claim 1 wherein the synthesized mammogram is matched in size and shape with the portion of the three dimensional reconstruction.

8. The method of claim 1 wherein the synthesized mammogram is displayed as a scout view.

9. The method of claim 1 wherein the synthesized mammogram is generated in response to a selection of a mammogram view at a user interface of a tomosynthesis system coupled to the display device.

10. The method of claim 1 including the step of retrieving a legacy mammogram from a storage device and displaying the legacy mammogram together with the synthesized mammogram on a display device.

11. The method of claim 1 wherein the tomosynthesis projection images are retrieved from a storage device coupled to a mammography system that includes the display device, and wherein the synthesized mammogram is displayed for comparison against a mammogram obtained by the mammography system.

12. The method of claim 1 wherein the x-ray tomosynthesis projection images are obtained by a dedicated tomosynthesis system that includes the display device and wherein the synthesized mammogram is displayed with at least one of the tomosynthesis projection images and a portion of a three-dimensional reconstructed tomosynthesis image.

13. The method of claim 1 wherein the x-ray tomosynthesis projection images are obtained by a combination mammography tomosynthesis system that includes the display device.

14. A system comprising:

a processor coupled to a computer readable medium having program code stored thereon, the program code being operable when executed upon by the processor to synthesize an x-ray mammogram using only one or more x-ray tomosynthesis projection images; and

a display device for displaying the synthesized mammogram wherein the program code for synthesizing the mammogram using the x-ray tomosynthesis projection images includes program code for generating a three dimensional reconstruction using the x-ray projection images, and wherein the program code for synthesizing the mammogram performs at least one of filtering and re-projecting of at least one of the x-ray tomosynthesis images and a portion of the three dimensional reconstruction to synthesize the mammogram.

15. The system of claim 14, wherein the program code for synthesizing the mammogram using the x-ray tomosynthesis projection images selects one of the x-ray tomosynthesis projection images for display on the display device.

16. The system of claim 15 wherein the program code for synthesizing the mammogram uses a tomosynthesis projection image taken when the x-ray source is normal to the digital detector.

17. A system comprising:

a processor coupled to a computer readable medium having program code stored thereon, the program code being operable when executed upon by the processor to synthesize an x-ray mammogram using only one or more x-ray tomosynthesis projection images; and

a display device for displaying the synthesized mammogram; and

an image acquisition device for obtaining the x-ray tomosynthesis projection images, the image acquisition device comprising an x-ray source, a digital detector and a controller;

wherein the program code is further operable when executed upon by the processor to reconstruct the tomosynthesis projection images into a three dimensional reconstructed image for synthesizing the mammogram and for generating a set of slabbed slices from the reconstructed image, re-projecting the set of slabbed slices to provide a two dimensional image and filtering the two dimensional image to provide the synthesized mammogram.

18. The system of claim 17 further comprising:

a storage device for storing the plurality of tomosynthesis projection images.