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SHIP-deficiency to increase megakaryocyte progenitor production

  • US 7,763,592 B1
  • Filed: 06/12/2006
  • Issued: 07/27/2010
  • Est. Priority Date: 11/20/2003
  • Status: Expired due to Fees
First Claim
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1. A method for increasing the proliferation of megakaryocyte progenitors in a human having impaired megakaryocyte production, comprising administering an effective amount of an interfering RNA molecule to the human, wherein the interfering RNA molecule is targeted to SH2-containing inositol-5-phosphatase (SHIP) mRNA, and wherein the proliferation of the megakaryocyte progenitors is thereby increased.

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