Biocompatible wound dressing

• US 7,763,769 B2
• Filed: 04/21/2006
• Issued: 07/27/2010
• Est. Priority Date: 02/16/2001
• Status: Expired due to Term

• Current Assignee: KCI Licensing Incorporated (3M Company)
• Original Assignee: KCI Licensing Incorporated (3M Company)
• Inventors: Tumey, David M., Johnson, Royce W.
• Primary Examiner(s): Lewis; Kim M
• Application Number:
  US11/409,116
• Publication Number:
  US 20060189910A1
• Time in Patent Office: 1,558 Days
• Field of Search: 602/48, 424/443, 424/447, 424/448, 424/449
• US Class Current: 602/48
• CPC Class Codes: A61F 13/0203 with fluid retention members
• CPC Class Codes: A61M 1/915 Constructional details of the pressure distribution manifold

Abstract

A biocompatible wound dressing comprised of a pad for insertion substantially into a wound site and a wound drape for sealing enclosure of the foam pad at the wound site. The pad, comprised of a foam or other like material having relatively few open cells in contact with the areas upon which cell growth is to be encouraged so as to avoid unwanted adhesions, but having sufficiently numerous open cells so that drainage and negative pressure therapy may continue unimpaired, is placed in fluid communication with a vacuum source for promotion of fluid drainage, as known in the art. The pad is further comprised of an ultra-low density fused-fibrous ceramic, or a bioabsorbable branched polymer, or cell growth enhancing matrix or scaffolding.

Claims

1. A biocompatible wound dressing, comprising:

a biocompatible pad shaped to conform to a wound site;

an air-tight seal removably adhered to said pad;

a negative pressure source in fluid communication with said pad;

a scaffold removably connected to a wound-contacting surface of the pad, the scaffold being adapted to facilitate cellular growth from the wound into the scaffold.

2. The biocompatible wound dressing of claim 1 wherein the biocompatible pad comprises an open-cell reticulated porous foam.

3. The biocompatible wound dressing of claim 1, further comprising a flexible tube communicating between said pad and said negative pressure source.

4. The biocompatible wound dressing of claim 3 further comprising a removable canister in fluid communication between said pad and said negative pressure source.

5. A biocompatible wound dressing comprising:

a pad comprised of a non-bioabsorbable substrate and a scaffold, the pad being shaped to conform to a wound site, the scaffold adapted to be absorbed or included by the wound, the scaffold being removably connected to a wound-contacting surface of the non-bioabsorbable substrate and adapted to allow cellular growth through the scaffold;

an air-tight-seal removably adhered to said pad; and

a negative pressure source in fluid communication with said scaffold.

6. The biocompatible wound dressing of claim 5 further comprising a flexible tube communicating between said pad and said negative pressure source.

7. The biocompatible wound dressing of claim 6 further comprising a removable canister in fluid communication between said pad and said negative pressure source.

8. A biocompatible wound dressing comprising:

a first pad comprised of a bioabsorbable or includable cell-growth enhancing matrix, shaped to conform to a wound site;

the bioabsorbable or includable cell-growth enhancing matrix comprising porous, highly reticulated material, the matrix being adapted to contact the wound surface and to be absorbed or included by the wound;

a negative pressure source in fluid communication with said pad;

a second pad comprised of a bioabsorbable or includable cell-growth enhancing matrix, adapted to connect to the surface of the first pad opposite the wound-facing surface and to cover the first pad when the first pad is partially absorbed or included by the wound; and

the bioabsorbable or includable cell-growth enhancing matrix of the second pad comprising porous, highly reticulated material, the matrix being adapted to contact the wound surface and to be absorbed or included by the wound;

wherein the matrix of the second pad is adapted to facilitate cellular growth from the wound through the matrix;

wherein the matrix of the first pad is adapted to facilitate cellular growth from the wound through the matrix.

9. The biocompatible wound dressing of claim 8 further comprising a removable canister in fluid communication between said pad and said negative pressure source.

10. The biocompatible wound dressing of claim 8, further comprising a third pad comprised of a non-bioabsorbable substrate removable coupled to the second pad, wherein the substrate defines a plurality of holes remote from the cell-growth enhancing matrices.

11. A biocompatible wound dressing comprising:

a pad comprised of a non-bioabsorbable substrate, and a bioabsorbable or includable cell-growth enhancing matrix removably coupled to the non-bioabsorbable substrate, the pad being shaped to conform to a wound site;

the cell-growth enhancing matrix comprising reticulated porous material formed into a plurality of sections and implanted into the substrate in the central portion of the pad, the matrix being adapted to contact the wound surface and to be absorbed or included by the wound;

the substrate defining a plurality of holes remote from the bioabsorbable or includable cell-growth enhancing matrix; and

wherein the pad is adapted to be fluidly connected to a negative pressure source.

12. The biocompatible wound dressing of claim 11 further comprising a removable canister in fluid communication between said pad and said negative pressure source.

13. The biocompatible wound dressing according to claim 11 further comprising a seal removably adhered to the pad.

14. The biocompatible wound dressing according to claim 11, wherein the matrix component provides an invadable space and scaffolding for cellular growth.

15. The biocompatible wound dressing according to claim 12, wherein the matrix is chosen from the group of collagen, dissolvable nylon, soluble plastics, fibrous ceramics, alginates, fibrin gels, fused fibers, and branched polymers.

16. The biocompatible wound dressing according to claim 12, wherein the non-bioabsorbable substrate is a polyurethane foam.

17. The biocompatible wound dressing according to claim 12, wherein the non-bioabsorbable substrate is a polyvinylalcohol foam.

18. A biocompatible wound dressing comprising:

a bioabsorbable or includable matrix having a surface adapted to be placed in contact with a tissue site at which new cell growth is desired, the bioabsorbable or includable matrix having an invadable space to facilitate cellular growth from the tissue site into the bioabsorbable or includable matrix;

a non-bioabsorbable porous substrate removably connected to the matrix; and

a flexible tube in fluid communication with at least one of the matrix and the substrate, the flexible tube further being adapted to be fluidly connected to a negative pressure source.

19. The biocompatible wound dressing according to claim 18 further comprising a seal removably adhered to the substrate.

20. The biocompatible wound dressing according to claim 18, wherein the matrix component provides an invadable space and scaffolding for cellular growth.

21. The biocompatible wound dressing according to claim 18, wherein the matrix is chosen from the group of collagen, dissolvable nylon, soluble plastics, fibrous ceramics, alginates, fibrin gels, fused fibers, and branched polymers.

22. The biocompatible wound dressing according to claim 18, wherein the substrate is a polyurethane foam.

23. The biocompatible wound dressing according to claim 18, wherein the substrate is a polyvinylalcohol foam.

24. A biocompatible wound dressing comprising:

a bioabsorbable pad having a surface adapted to be placed in contact with a tissue site at which new cell growth is desired, the bioabsorbable pad having an invadable space to facilitate cellular growth from the tissue site into the bioabsorbable pad; and

a flexible tube in fluid communication with the bioabsorbable pad, the flexible tube further being adapted to be fluidly connected to a negative pressure source, the flexible tube delivering negative pressure to the bioabsorbable pad.

25. The biocompatible wound dressing according to claim 24, wherein the bioabsorbable pad is a bioabsorbable branched polymer.

26. The biocompatible wound dressing according to claim 24 further comprising a seal removably adhered to the pad.

27. The biocompatible wound dressing according to claim 24, wherein the bioabsorbable pad is porous to allow distribution of negative pressure to the tissue site.

28. The biocompatible wound dressing according to claim 24 further comprising a removable canister in fluid communication with the flexible tube.

29. A method of providing negative pressure therapy to a wound comprising:

positioning a pad having a bioabsorbable or includable component and a non-bioabsorbable component adjacent a wound such that the bioabsorbable or includable component contacts the wound;

delivering a negative pressure to the wound through the pad to promote growth of new cells at the wound and within the bioabsorbable or includable component; and

removing the non-bioabsorbable component following delivery of the negative pressure.

30. The method according to claim 29 further comprising:

allowing the bioabsorbable or includable component to remain in the wound following removal of the non-bioabsorbable component.

31. The method according to claim 29 further comprising:

positioning a second pad having a non-bioabsorbable component in contact with the bioabsorbable or includable component of the first pad.

32. The method according to claim 29 further comprising:

positioning a second pad having a bioabsorbable or includable component and a non-bioabsorbable component within the wound such that the bioabsorbable or includable component of the second pad contacts the bioabsorbable or includable component of the first pad;

delivering a negative pressure to the second pad to promote growth of new cells within at least one of the bioabsorbable or includable component of the first pad and the bioabsorbable or includable component of second pad.

33. The method according to claim 32 further comprising:

removing the non-bioabsorbable component of the second pad following delivery of the negative pressure.

34. The method according to claim 29 further comprising:

covering the wound and pad with a drape to assist in maintaining the negative pressure at the wound.

35. The method according to claim 29, wherein the negative pressure is sub atmospheric pressure.

36. The method according to claim 29, wherein the bioabsorbable or includable component is capable of providing an invadable space and scaffolding for cellular growth.

37. The method according to claim 29, wherein the bioabsorbable or includable component is chosen from the group of collagen, dissolvable nylon, soluble plastics, fibrous ceramics, alginates, fibrin gels, fused fibers, and branched polymers.

38. The method according to claim 29, wherein the non-bioabsorbable component is a polyurethane foam.

39. The method according to claim 29, wherein the non-bioabsorbable component is a polyvinylalcohol foam.