Water vapor monitoring apparatus
First Claim
1. An apparatus for the monitoring and the control of water vapor in a freeze-drying process comprising(a) a sterilizable freeze-drying device and(b) an optical spectrometer isolated from the internal volume of the sterilizable freeze-drying device by a window, wherein said optical spectrometer measures the water vapor present in the atmosphere of the freeze-drying device by emitting a light radiation in the atmosphere of the freeze-drying device through the window, said window being located in a wall of the volume defined by the freeze-drying device,wherein the optical spectrometer comprises an optical emitter and an optical detector located outside said freeze drying device, said optical emitter being separated from the internal volume of the freeze drying device by a first window located in a wall of said freeze drying device, and said optical detector being separated from the internal volume of the freeze drying device by a second window located in a wall of said freeze drying device.
2 Assignments
0 Petitions
Accused Products
Abstract
A freeze-drying device for the monitoring and control of water vapor in a freeze-drying process, comprising an optical spectrometer, and methods of using same to monitor and control the amount of water vapor in said process under sterile conditions.
26 Citations
5 Claims
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1. An apparatus for the monitoring and the control of water vapor in a freeze-drying process comprising
(a) a sterilizable freeze-drying device and (b) an optical spectrometer isolated from the internal volume of the sterilizable freeze-drying device by a window, wherein said optical spectrometer measures the water vapor present in the atmosphere of the freeze-drying device by emitting a light radiation in the atmosphere of the freeze-drying device through the window, said window being located in a wall of the volume defined by the freeze-drying device, wherein the optical spectrometer comprises an optical emitter and an optical detector located outside said freeze drying device, said optical emitter being separated from the internal volume of the freeze drying device by a first window located in a wall of said freeze drying device, and said optical detector being separated from the internal volume of the freeze drying device by a second window located in a wall of said freeze drying device.
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3. An apparatus for the monitoring and the control of water vapor in a freeze drying process which comprises
(a) an optical spectrometer comprising an optical emitter and an optical detector and (b) a freeze-drying device comprising a freeze-drying chamber and a condenser which can be separated from the freeze-drying chamber by a valve, and wherein, the optical emitter is outside the freeze-drying device, separated from the internal volume of the freeze-drying device by a window located in a wall of said freeze-drying device, the freeze-drying device further comprising at least one reflector located inside or outside the freeze-drying device at a defined distance from the optical emitter and from the detector so as to reflect a light radiation emitted by the optical emitter toward the optical detector; wherein the optical emitter and the optical detector of the optical spectrometer are located at the opposite side and outside of said freeze-drying device said optical emitter being separated from the internal volume of the freeze drying device by a first window located in a wall of said freeze drying device, and said optical detector being separated from the internal volume of the freeze drying device by a second window located in a wall of said freeze drying device opposite to the optical emitter. - View Dependent Claims (4, 5)
Specification