Pleural effusion treatment device, method and material
First Claim
1. A method of treating a patient for pleural effusion, the method comprising:
- percutaneously delivering an effective amount of an adhesive material to a pleural space of the patient by ejecting the adhesive material from a lumen of a percutaneous delivery device into the pleural space so as to cause a visceral pleura and a parietal pleura of the patient to adhere to one another such that excess fluid flow into the pleural space is inhibited; and
mixing components of the adhesive material in the delivery device prior to the ejecting step,wherein the adhesive material has an adhesive strength up to 1.5 psi.
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Accused Products
Abstract
The invention discloses a method of treating a patient for pleural effusion comprising percutaneously delivering an adhesive material to a pleural space of the patient. Suitable adhesive materials for performing any of the embodiments of the methods of the invention can be selected from the group consisting of hydrogels, collagen, poly(lactic acid), poly(glycolide), cyanoacrylates, glutaraldehyde, PEG, protein, and polysaccharide and derivatives thereof. The invention also discloses a pleural effusion treatment apparatus comprising an adhesive material adapted to adhere pleural membranes defining a pleural space and a pleural space access member adapted to deliver the adhesive material to the pleural space.
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Citations
14 Claims
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1. A method of treating a patient for pleural effusion, the method comprising:
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percutaneously delivering an effective amount of an adhesive material to a pleural space of the patient by ejecting the adhesive material from a lumen of a percutaneous delivery device into the pleural space so as to cause a visceral pleura and a parietal pleura of the patient to adhere to one another such that excess fluid flow into the pleural space is inhibited; and mixing components of the adhesive material in the delivery device prior to the ejecting step, wherein the adhesive material has an adhesive strength up to 1.5 psi. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method of treating a patient for pleural effusion, the method comprising:
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percutaneously inserting a pleural space access member into the patient, wherein the pleural space access member comprises a suction device and a device for delivering an adhesive material; and percutaneously delivering an effective amount of an adhesive material to a pleural space of the patient by ejecting the adhesive material from a lumen of a percutaneous delivery device into the pleural space so as to cause a visceral pleura and a parietal pleura of the patient to adhere to one another such that excess fluid flow into the pleural space is inhibited, wherein the adhesive material has a viscosity level of 1.1 centipoise or higher. - View Dependent Claims (10, 11)
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12. A method of treating a patient for pleural effusion, the method comprising:
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percutaneously delivering an effective amount of an adhesive material to a pleural space of the patient by ejecting the adhesive material from a lumen of a percutaneous delivery device into the pleural space so as to cause a visceral pleura and a parietal pleura of the patient to adhere to one another such that excess fluid flow into the pleural space is inhibited; wherein the delivering step comprises delivering the adhesive material having an adhesive strength up to 1.5 psi.
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13. A method of treating a patient for pleural effusion, the method comprising:
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percutaneously delivering an effective amount of an adhesive material to a pleural space of the patient by ejecting the adhesive material from a lumen of a percutaneous delivery device into the pleural space so as to cause a visceral pleura and a parietal pleura of the patient to adhere to one another such that excess fluid flow into the pleural space is inhibited; wherein the delivering step comprises delivering the adhesive material having an adhesive strength of between 0.2-0.6 psi.
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14. A method of treating a patient for pleural effusion, the method comprising:
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percutaneously delivering an effective amount of an adhesive material to a pleural space of the patient by ejecting the adhesive material from a lumen of a percutaneous delivery device into the pleural space so as to cause a visceral pleura and a parietal pleura of the patient to adhere to one another such that excess fluid flow into the pleural space is inhibited; wherein the adhesive material having an adhesive strength up to 1.5 psi; wherein the adhesive material comprises a material selected from the group consisting of hydrogels, proteins, polymers and cross-linking agents; and wherein the cross-linking agent material comprises a material selected from the group consisting of glutaraldehyde and stable polyaldehyde.
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Specification