Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction
First Claim
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1. A method of assessing cerebral vasculature status in a patient, comprising the steps of:
- positioning a sensor in communication with a body fluid;
determining in a processor a baseline concentration of an indicator of the presence of NO or an NO metabolite;
monitoring changes from the baseline indicative of the cerebral vascular status; and
activating a signal in response to a change from the baseline by more than a predetermined limit.
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Abstract
A sensor is disclosed, for implantation within a blood vessel to monitor a substance in or property of blood. In one embodiment, the sensor detects nitric oxide or a nitric oxide metabolite. In another embodiment, other substances such as glutamate, aspartate, arginine, citrulline, acetylcholine, calcium, potassium, or dopamine are monitored. The sensor may be attached to a support structure such as a stent, guidewire, or catheter. In a further embodiment, a catheter is disclosed that extracts patient fluid to a sensor outside the body for monitoring a substance or property of the patient fluid. Methods are also disclosed.
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Citations
11 Claims
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1. A method of assessing cerebral vasculature status in a patient, comprising the steps of:
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positioning a sensor in communication with a body fluid; determining in a processor a baseline concentration of an indicator of the presence of NO or an NO metabolite; monitoring changes from the baseline indicative of the cerebral vascular status; and activating a signal in response to a change from the baseline by more than a predetermined limit. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification