Modification of airways by application of microwave energy

• US 7,770,584 B2
• Filed: 12/04/2008
• Issued: 08/10/2010
• Est. Priority Date: 04/07/1997
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Asthmatx, Inc. (Boston Scientific Corporation)
• Inventors: Keast, Thomas M., Laufer, Michael D., Danek, Christopher J., Loomas, Bryan E.
• Primary Examiner(s): Farah; Ahmed M
• Application Number:
  US12/328,596
• Publication Number:
  US 20090112203A1
• Time in Patent Office: 614 Days
• Field of Search: 607/88, 607/89, 607/92, 607/101, 607/102, 128/898, 606/15
• US Class Current: 128/898
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 18/04 by heating by applying electromagnetic radiation A61B18/18; hyperthermia using electric or magnetic fields, radiation or ultrasound A61N
• CPC Class Codes: A61B 18/08 by means of electrically-heated probes
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 2017/003 Steerable
• CPC Class Codes: A61B 2018/00083 low, i.e. electrically insulating
• CPC Class Codes: A61B 2018/00214 Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/0022 Balloons
• CPC Class Codes: A61B 2018/00267 having a basket shaped structure
• CPC Class Codes: A61B 2018/00434 Neural system
• CPC Class Codes: A61B 2018/00541 Lung or bronchi
• CPC Class Codes: A61B 2018/00654 with individual control of each of a plurality of energy emitting elements
• CPC Class Codes: A61B 2018/00666 using a threshold value
• CPC Class Codes: A61B 2018/00678 upper
• CPC Class Codes: A61B 2018/00761 Duration
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00803 with temperature prediction
• CPC Class Codes: A61B 2018/0212 using an instrument inserted into a body lumen, e.g. catheter
• CPC Class Codes: A61B 2090/3614 : using optical fibre
• CPC Class Codes: A61F 2007/0018 : Trunk or parts thereof
• CPC Class Codes: A61F 2007/0059 : with an open fluid circuit
• CPC Class Codes: A61F 2007/126 : for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/123 : using a flexible balloon containing the thermal element
• CPC Class Codes: A61M 2025/0096 : being laterally outward extensions or tools, e.g. hooks or fibres
• CPC Class Codes: A61M 2210/1039 : Lungs
• CPC Class Codes: A61M 25/0043 : characterised by structural features
• CPC Class Codes: A61M 29/00 : Dilators with or without means for introducing media, e.g. remedies instruments for performing visual medical inspections of cavities or tubes of the body A61B1/00
• CPC Class Codes: A61M 29/02 : Dilators made of swellable material balloon catheters for angioplasty A61M25/104
• CPC Class Codes: A61N 1/06 : for high-frequency therapy
• CPC Class Codes: A61N 1/403 : for thermotherapy, e.g. hyperthermia
• CPC Class Codes: A61N 5/00 : Radiation therapy ultrasound therapy A61N7/00; devices or apparatus applicable to both therapy and diagnosis A61B6/00

Abstract

Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung. The damaging of lung cells, damaging tissue, causing trauma, and destroying airway smooth muscle tone with the apparatus may be any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.

Claims

1. A method of treating an airway in an asthmatic lung of a patient, comprising:

inserting an elongated shaft into the airway, wherein the elongated shaft has a distal end, and wherein an energy transfer device is at the distal end of the elongated shaft;

delivering microwave energy to tissue structures of an airway wall at a treatment site via the energy transfer device, whereby the microwave energy causes the airway to undergo a transformation effective to reduce asthma symptoms.

2. The method of claim 1, further comprising:

(a) terminating delivery of microwave energy to the treatment site;

(b) moving the energy transfer device proximally to a new treatment site along the airway;

(c) delivering microwave energy to tissue structures of the airway wall at the new treatment site; and

repeating acts a-c along the airway.