Selective renal cannulation and infusion systems and methods
First Claim
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1. A renal infusion system, comprising:
- an infusion catheter having a bifurcated distal end with a first branch and second branch, said branches being biased to deploy laterally when unconstrained; and
a delivery sheath having a lumen which receives the infusion catheter and constrains the first branch and second branch;
wherein one of the first and second branches opens laterally through a distal opening of the delivery sheath while the other of the first and second branches remains fully constrained within the delivery sheath, andwherein the first branch comprises a first branch lumen and a first branch infusion port, and the second branch comprises a second branch lumen and a second branch infusion port.
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Abstract
Renal infusion systems include an infusion catheter having a bifurcated distal end with a first branch and second branch, the branches being biased to deploy laterally when unconstrained. Systems also include a delivery sheath having a lumen which receives the infusion catheter and constrains the first branch and second branch. A distal opening of the delivery sheath is formed asymmetrically to allow one of the first and second branches to open laterally while the other of the branches remains constrained. Methods of using renal infusion systems are also provided.
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Citations
25 Claims
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1. A renal infusion system, comprising:
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an infusion catheter having a bifurcated distal end with a first branch and second branch, said branches being biased to deploy laterally when unconstrained; and a delivery sheath having a lumen which receives the infusion catheter and constrains the first branch and second branch; wherein one of the first and second branches opens laterally through a distal opening of the delivery sheath while the other of the first and second branches remains fully constrained within the delivery sheath, and wherein the first branch comprises a first branch lumen and a first branch infusion port, and the second branch comprises a second branch lumen and a second branch infusion port. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An infusion catheter, comprising:
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a catheter body having a distal end with a first branch, said branch being biased to deploy laterally when unconstrained; and a first valve structure disposed between a main lumen in the catheter body and a branch lumen in the first branch, wherein said first valve structure is closed when the first branch is undeployed and opens in response to lateral deployment of the first branch. - View Dependent Claims (12, 13, 14, 15)
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16. A renal infusion system, comprising:
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a delivery sheath configured for placement within an aorta of a patient; a first catheter branch configured for advancement through the delivery sheath toward a first renal artery of the patient; a first flow path that passes through the first catheter branch to provide a first fluid flow toward the first renal artery; a first valve that regulates the first flow path when the first branch is in a constrained and released configuration; a second catheter branch configured for advancement through the delivery sheath toward a second renal artery of the patient; a second flow path that passes through the second catheter branch to provide a second fluid flow toward the second renal artery; and a second valve that regulates the second flow path when the second branch is in a constrained and released configuration; and wherein the first fluid flow through the first flow path is greater when the first branch is in the released configuration than when it is in the constrained configuration. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25)
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Specification