Mixing and dispensing homogeneous compounds of a reactant on a surface
First Claim
1. A method for the homogeneous mixing and distribution, on a surface, of at least one reactant carried by a carrier fluid in laminar flow, comprising the following essential steps:
- a) a reaction chamber is provided, which chamber has;
at least one reaction surface on which the reactant is capable of being fixed, directly or indirectly, optionally reversibly,at least three fluid inlets/outlets, andat least one reservoir, the volume of which is fixed, the fixed-volume reservoir being able to communicate, firstly, with the reaction chamber and, secondly, with the outside of the reaction chamber via an injection orifice equipped with hermetic closure means;
b) optionally, the injection orifice of the fixed-volume reservoirs is hermetically closed or kept hermetically closed and then at least one fluid other than the carrier fluid containing the reactant is introduced into the reaction chamber via at least one inlet/outlet of the reaction chamber;
c) the carrier fluid containing the reactant is injected into at least one of the fixed-volume reservoirs;
d) the carrier fluid containing the reactant is circulated between the fixed-volume reservoir, the reaction chamber and a variable-volume reservoir able to communicate independently with the reaction chamber via valves placed between the variable-volume reservoir and each of the inlets/outlets of the reaction chamber using a means for circulating the fluids in the reaction chamber and the fluid loop;
e) step d) is repeated by successively selecting the various inlets/outlets;
f) optionally, steps b) and/or c) and/or d) and/or e) are repeated.
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Accused Products
Abstract
A method for mixing and dispensing compounds, at least one reactant in a carrier fluid in laminar flow, and a cell for implementing the method. The cell includes a reaction chamber having a reaction surface where the reactant can be fixed, directly or indirectly, at least three fluid inlets/outlets, a fixed volume reservoir in communication with the reaction chamber and outside the reaction chamber via injection orifice (27), a fluid loop including a feeding port, an extraction port and a variable volume reservoir adapted to communicate independently with the reaction chamber via each of its inlets/outlets; device for circulating fluids in the reaction chamber and the fluid loop. The method and cell can be used to prepare homogeneous surface films, or to carry out “target-probe” identification reactions.
8 Citations
24 Claims
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1. A method for the homogeneous mixing and distribution, on a surface, of at least one reactant carried by a carrier fluid in laminar flow, comprising the following essential steps:
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a) a reaction chamber is provided, which chamber has; at least one reaction surface on which the reactant is capable of being fixed, directly or indirectly, optionally reversibly, at least three fluid inlets/outlets, and at least one reservoir, the volume of which is fixed, the fixed-volume reservoir being able to communicate, firstly, with the reaction chamber and, secondly, with the outside of the reaction chamber via an injection orifice equipped with hermetic closure means; b) optionally, the injection orifice of the fixed-volume reservoirs is hermetically closed or kept hermetically closed and then at least one fluid other than the carrier fluid containing the reactant is introduced into the reaction chamber via at least one inlet/outlet of the reaction chamber; c) the carrier fluid containing the reactant is injected into at least one of the fixed-volume reservoirs; d) the carrier fluid containing the reactant is circulated between the fixed-volume reservoir, the reaction chamber and a variable-volume reservoir able to communicate independently with the reaction chamber via valves placed between the variable-volume reservoir and each of the inlets/outlets of the reaction chamber using a means for circulating the fluids in the reaction chamber and the fluid loop; e) step d) is repeated by successively selecting the various inlets/outlets; f) optionally, steps b) and/or c) and/or d) and/or e) are repeated. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A cell for homogeneously mixing and distributing, on a surface, at least one reactant carried by a carrier fluid in laminar flow, comprising:
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a reaction chamber which has; at least one reaction surface on which the reactant is capable of being fixed, directly or indirectly, optionally reversibly, at least three fluid inlets/outlets, and at least one reservoir, the volume of which is fixed, the fixed-volume reservoir being able to communicate, firstly, with the reaction chamber and, secondly, with the outside of the reaction chamber via an injection orifice equipped with hermetic closure means, a fluid loop comprising at least one feed port, at least one extraction port and at least one reservoir, the volume of which is variable, the variable-volume reservoir being able to communicate independently with the reaction chamber via valves placed between the variable-volume reservoir and each of the inlets/outlets; means for circulating the fluids in the reaction chamber and in the fluid loop. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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Specification