Guided access to lung tissues

• US 7,775,968 B2
• Filed: 06/14/2005
• Issued: 08/17/2010
• Est. Priority Date: 06/14/2004
• Status: Expired due to Fees

• Current Assignee: EKOS Corporation (Boston Scientific Corporation)
• Original Assignee: PneumRx, Inc. (Boston Scientific Corporation)
• Inventors: Mathis, Mark
• Primary Examiner(s): KASZTEJNA, MATTHEW JOHN
• Application Number:
  US11/153,295
• Publication Number:
  US 20050288549A1
• Time in Patent Office: 1,890 Days
• Field of Search: 600/116, 600/153, 604/509
• US Class Current: 600/104
• CPC Class Codes: A61B 1/0014 Fastening element for attaching accessories to the outside of an endoscope, e.g. clips, clamps or bands
• CPC Class Codes: A61B 1/018 for receiving instruments
• CPC Class Codes: A61B 1/2676 Bronchoscopes
• CPC Class Codes: A61B 17/3403 Needle locating or guiding means guides for suture needles A61B17/0482; guiding or tracking by nuclear magnetic resonance G01R33/285
• CPC Class Codes: A61B 2010/045 Needles pointed biopsy devices with vacuum aspiration A61B10/0283

Abstract

This invention relates generally to lung access devices and methods of using the devices to gain access to the interior of a lung or to the mediastinal space around the lung. In particular, the invention relates to auxiliary access devices and tools for use with conventional bronchoscopes or other endoscopes to enable the delivery of more and larger devices to a target site than is currently possible through a typical endoscope or bronchoscope.

Claims

1. A method of accessing a subject'"'"'s lung or surrounding tissue of said subject'"'"'s lung, the method comprising:

(a) advancing a distal end of an imaging device into the subject'"'"'s lung so that a proximal end of the imaging device is located outside said subject'"'"'s lung;

(b) positioning a guide element relative to the imaging device so that the guide element extends continuously from a first end of the guide element disposed adjacent the proximal end of the imaging device, distally through a lumen of the imaging device toward a distal end of the imaging device and then returning proximally from the distal end of the imaging device outside the imaging device to a second end of the guide element;

(c) wherein the first and second ends of the guide element are disposed outside the lung after the imaging device is advanced so that the guide element between the second end and the distal end of the advanced imaging device is accessible to direct an instrument distally into the subject'"'"'s lung; and

(d) advancing the instrument over the guide element by receiving the second end of the guide element in a lumen of the instrument and advancing the instrument distally over the guide element from the second end to the distal end of the imaging device.

2. The method of claim 1, wherein more than one guide element returns proximally from the distal end of the imaging device outside the imaging device toward the proximal end of the imaging device so that an associated end of each guide element is accessible from outside the patient.

3. The method of claim 1, wherein said guide element has a distal end, wherein said distal end is adapted to be placed within a subject'"'"'s body and is to be connected to said instrument.

4. The method of claim 1, wherein said guide element is a guide wire.

5. The method of claim 1, wherein said guide element comprises a needle guide.

6. The method of claim 1, further comprising tensioning of the guide element from outside the subject'"'"'s lung so as to bend the guide element adjacent the distal end of the imaging device.

7. The method of claim 6, wherein the tensioning of the guide element comprising applying tension adjacent the second end of the guide element, and wherein the bending of the guide element is done so as to guide the imaging device with the bent guide element while advancing the imaging device into the subject'"'"'s lung.

8. The method of claim 6, wherein the tensioning of the guide element comprises applying tension adjacent the second end of the guide element, and wherein the bending of the guide element is done so as to guide the instrument with the bent guide element while advancing the instrument into the subject'"'"'s lung.

9. The method of claim 1, wherein the instrument has an outer diameter larger than a working channel diameter of the imaging device.

10. The method of claim 1, wherein said lumen of said imaging device comprises a working channel.

11. The method of claim 10, wherein at least a portion of said guide element is disposed inside said working channel.

12. The method of claim 10, further comprising an instrument connected to said guide element located outside said working channel.

13. The method of claim 12, wherein said instrument being connected to said guide element is located within or traversing said distal end of said working channel.

14. The method of claim 12, wherein said instrument is adapted to perform biopsy.

15. The method of claim 12, wherein said instrument is adapted to image bodily tissue.

16. The method of claim 12, wherein said instrument is adapted to deliver a pharmaceutical composition to the lung.

17. The method of claim 1, wherein said imaging device comprises a bronchoscope.

18. A method of accessing a subject'"'"'s lung or surrounding tissue of said subject'"'"'s lung, the method comprising:

(a) advancing a distal end of an imaging device into the subject'"'"'s lung so that a proximal end of the imaging device is located outside said subject'"'"'s lung; and

(b) positioning a guide element relative to the imaging device so that the guide element extends continuously from a first end of the guide element disposed adjacent the proximal end of the imaging device, distally through a lumen of the imaging device toward a distal end of the imaging device and then returning proximally from the distal end of the imaging device outside the imaging device to a second end of the guide element; and

(c) wherein the first and second ends of the guide element are disposed outside the lung after the imaging device is advanced so that the guide element between the second end and the distal end of the advanced imaging device is accessible to direct an instrument distally into the subject'"'"'s lung, and wherein said instrument comprises a needle guide.

19. The method of claim 18, wherein said needle guide comprises a side port.

20. A method of accessing a subject'"'"'s lung or surrounding tissue of said subject'"'"'s lung, the method comprising:

(a) advancing a distal end of an imaging device into the subject'"'"'s lung so that a proximal end of the imaging device is located outside said subject'"'"'s lung; and

(b) positioning a guide element relative to the imaging device so that the guide element extends continuously from a first end of the guide element disposed adjacent the proximal end of the imaging device, distally through a lumen of the imaging device toward a distal end of the imaging device and then returning proximally from the distal end of the imaging device outside the imaging device to a second end of the guide element; and

(c) wherein the first and second ends of the guide element are disposed outside the lung after the imaging device is advanced so that the guide element between the second end and the distal end of the advanced imaging device is accessible to direct a balloon distally into the subject'"'"'s lung.

21. The method of claim 20, wherein said balloon comprises a lumen with at least one side port.

22. A method of accessing a subject'"'"'s lung or surrounding tissue of said subject'"'"'s lung, the method comprising:

(a) advancing a distal end of an imaging device into the subject'"'"'s lung so that a proximal end of the imaging device is located outside said subject'"'"'s lung; and

(b) positioning a guide element relative to the imaging device so that the guide element extends continuously from a first end of the guide element disposed adjacent the proximal end of the imaging device, distally through a lumen of the imaging device toward a distal end of the imaging device and then returning proximally from the distal end of the imaging device outside the imaging device to a second end of the guide element; and

(c) wherein the first and second ends of the guide element are disposed outside the lung after the imaging device is advanced so that the guide element between the second end and the distal end of the advanced imaging device is accessible to direct an instrument distally into the subject'"'"'s lung, and wherein said instrument comprises a catheter connected to a balloon.

23. A method of accessing a subject'"'"'s lung or surrounding tissue of said subject'"'"'s lung, the method comprising:

(a) advancing a distal end of an imaging device into the subject'"'"'s lung so that a proximal end of the imaging device is located outside said subject'"'"'s lung; and

(b) positioning a guide element relative to the imaging device so that the guide element extends continuously from a first end of the guide element disposed adjacent the proximal end of the imaging device, distally through a lumen of the imaging device toward a distal end of the imaging device and then returning proximally from the distal end of the imaging device outside the imaging device to a second end of the guide element; and

(c) wherein the first and second ends of the guide element are disposed outside the lung after the imaging device is advanced so that the guide element between the second end and the distal end of the advanced imaging device is accessible to direct an instrument distally into the subject'"'"'s lung, and wherein said instrument comprises a plurality of needle guides covered by an extendable sleeve.

24. A method of accessing a subject'"'"'s lung or surrounding tissue of said subject'"'"'s lung, the method comprising:

(a) advancing a distal end of an imaging device into the subject'"'"'s lung so that a proximal end of the imaging device is located outside said subject'"'"'s lung;

(b) positioning a guide element relative to the imaging device so that the guide element extends continuously from a first end of the guide element disposed adjacent the proximal end of the imaging device, distally through a lumen of the imaging device toward a distal end of the imaging device and then returning proximally from the distal end of the imaging device outside the imaging device to a second end of the guide element;

(c) wherein the first and second ends of the guide element are disposed outside the lung after the imaging device is advanced so that the guide element between the second end and the distal end of the advanced imaging device is accessible to direct an instrument distally into the subject'"'"'s lung, and wherein the guide element has a lumen extending between the second and the distal end of the advanced imaging device; and

(d) advancing the instrument from the second end of the guide element distally through the lumen of the guide element toward the distal end of the advanced imaging device.