Cassette and embedding assembly for handling and holding tissue samples during processing, embedding and microtome procedures, staging devices therefore, and methods therefor
First Claim
1. A cassette for holding a tissue sample, comprising:
- a body including a perforated bottom wall and a plurality of perforated side walls extending upwardly with respect to said bottom wall to define an interior space for receiving the tissue sample;
said bottom wall and said plurality of side walls being constructed of a material capable of being successfully sectioned in a microtome and resistant to degradation during histologic tissue processing, wherein said plurality of side walls comprise first and second side walls each having a length and extending upwardly from opposite edges of said bottom wall, at least one of said first and second side walls including portions angling toward the other of the first and second side walls on the opposite edge of the bottom wall to define an outwardly projecting portion proximate a midpoint along said length of said at least one side wall.
1 Assignment
0 Petitions
Accused Products
Abstract
The disclosure relates to a cassette, frame and mold for holding a tissue sample during an embedding and mircotoming process, and related methods. The cassette is sectionable in a microtome and includes a body with a bottom wall and a plurality of side walls. First and second side walls are generally V-shaped to present an apex of the “V” to the microtome blade. A lid of the cassette is stiffer than the bottom wall of the cassette to assist with positioning the tissue sample. The side walls of the cassette are perforated so as to significantly reduce the amount of cassette material that must be cut by the microtome blade. In one embodiment, to additionally reduce blade wear the ribs on one side wall are offset lengthwise relative to the ribs on an opposite side wall. An upper flange of the cassette includes depressions configured to register with detents in the frame.
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Citations
8 Claims
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1. A cassette for holding a tissue sample, comprising:
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a body including a perforated bottom wall and a plurality of perforated side walls extending upwardly with respect to said bottom wall to define an interior space for receiving the tissue sample; said bottom wall and said plurality of side walls being constructed of a material capable of being successfully sectioned in a microtome and resistant to degradation during histologic tissue processing, wherein said plurality of side walls comprise first and second side walls each having a length and extending upwardly from opposite edges of said bottom wall, at least one of said first and second side walls including portions angling toward the other of the first and second side walls on the opposite edge of the bottom wall to define an outwardly projecting portion proximate a midpoint along said length of said at least one side wall. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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Specification