Elasticity and viscosity measuring apparatus

• US 7,777,891 B2
• Filed: 09/20/2006
• Issued: 08/17/2010
• Est. Priority Date: 09/20/2005
• Status: Expired due to Fees

• Current Assignee: Sumitomo Electric Industries Limited (Sumitomo Corporation)
• Original Assignee: Sumitomo Electric Industries Limited (Sumitomo Corporation)
• Inventors: Hasegawa, Takemi
• Primary Examiner(s): Connolly; Patrick J
• Application Number:
  US12/067,439
• Publication Number:
  US 20090073453A1
• Time in Patent Office: 1,427 Days
• Field of Search: 356/450, 356/477, 356/484, 356/485
• US Class Current: 356/485
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/0066 Optical coherence imaging
• CPC Class Codes: G01N 2021/638 Brillouin effect, e.g. stimulated Brillouin effect
• CPC Class Codes: G01N 21/4795 spatially resolved investigating of object in scattering medium in vivo A61B

Abstract

Brillouin scattered light is used to measure the distribution of elasticity and viscosity in a measurement object without contact and in a noninvasive and simpler manner. Measuring light emitted from a light source is directed from a light probe onto a measurement object, and scattered light is received by the light probe. A control computer analyzes the light spectrum of scattered light received by the light probe, calculates at least one parameter selected from the center frequency and the linewidth of the elastic wave scattered components as viscoelastic information, matches the viscoelastic information with the position of a target area in the measurement object, and outputs image information. The position information of the target area in the measurement object is acquired by photographing light spots of guide light with a camera provided to the light probe.

Claims

1. An elasticity and viscosity measuring apparatus comprising:

excitation light generating means for generating modulated excitation light;

an optical system for focusing the excitation light to a focusing position on a measurement object and capturing scattered light generated by the measurement object;

locally oscillated light generating means for generating locally oscillated light;

multiplexing means for multiplexing the captured scattered light and locally oscillated light;

optical detection means for photoelectrically converting the multiplexed light and generating a photoelectric current;

a filter for selecting and extracting part of an AC component of the photoelectric current;

frequency-selective power detection means for selecting and measuring, based on the electric power of the extracted photoelectric current, a frequency component related to modulating the excitation light; and

analyzing means for calculating the light spectrum of the scattered light and obtaining at least one parameter selected from the strength of the scattered light, the frequency, and the linewidth based on the elastic waves in the measurement object;

wherein

the optical system selects and captures part of the scattered light that forms an angle of 90 degrees or greater in relation to the wave number vector of the excitation light.

2. The elasticity and viscosity measuring apparatus according to claim 1, further comprising

focused position measuring means for measuring the focused position of the excitation light.

3. The elasticity and viscosity measuring apparatus according to claim 1, wherein

the excitation light is a periodic pulse train;

and

the repetition frequency f, the duty ratio d, the light wavelength λ

, and the average power P satisfy the following relationships;

f≧

30 kHz, d≧

0.2, 700 nm≧

λ

1100 nm, P≧

3.5 mW.

4. The elasticity and viscosity measuring apparatus according to claim 1, wherein

the excitation light is a pulse train with a repetition frequency f₁;

the locally oscillated light is modulated in strength or polarization at a frequency f₂; and

the frequency-selective power detection means selectively detects a frequency component at a frequency (f₁-f₂).

5. The elasticity and viscosity measuring apparatus according to claim 1, wherein

the excitation light generating means and the locally oscillated light generating means share a single laser light source;

and

the transmission frequency of the filter is variable.

6. The elasticity and viscosity measuring apparatus according to claim 1, wherein

the excitation light generating means and the locally oscillated light generating means have separate laser light sources;

the frequency of at least one of the laser light sources is variable; and

the apparatus comprises frequency difference measuring means for measuring the difference in optical frequencies between the excitation light and the locally oscillated light.

7. The elasticity and viscosity measuring apparatus according to claim 1, wherein

the bandwidth of the filter is 10 MHz to 1 GHz.

8. The elasticity and viscosity measuring apparatus according to claim 1, wherein

the bandwidth of the filter is variable;

and

the filter bandwidth can be adjusted to coincide with the Brillouin linewidth of the measurement object.

9. The elasticity and viscosity measuring apparatus according to claim 3, wherein

the excitation light is a pulse train with a cyclic frequency f₁;

the locally oscillated light is modulated in strength or polarization at a frequency f₂; and

the frequency-selective power detection means selectively detects a frequency component at a frequency (f₁-f₂).