Component measuring instrument and chip

• US 7,780,610 B2
• Filed: 09/19/2001
• Issued: 08/24/2010
• Est. Priority Date: 05/01/2000
• Status: Active Grant

• Current Assignee: Terumo Kabushiki Kaisha
• Original Assignee: Terumo Kabushiki Kaisha
• Inventors: Sonoda, Kouichi, Nishikawa, Hisao, Takinami, Masao
• Primary Examiner(s): Hindenburg; Max
• Assistant Examiner(s): Lloyd; Emily M
• Application Number:
  US10/488,311
• Publication Number:
  US 20040210247A1
• Time in Patent Office: 3,261 Days
• Field of Search: 600/583, 600/573, 600/576, 600/578, 600/584, 606/181, 606/182
• US Class Current: 600/583
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/1519 comprising driving means, e.g. a spring, for propelling the piercing unit
• CPC Class Codes: A61B 5/15194 fully automatically retracted, i.e. the retraction does not require a deliberate action by the user, e.g. by terminating the contact with the patient's skin

Abstract

It is an object of the present invention to provide a component measuring instrument with which a predetermined component in blood can be measured securely and in a short time. The component measuring instrument, which is used by mounting therein a chip having a puncture needle, includes: a specimen sampling portion application portion to which a specimen sampling portion to be punctured is applied; a puncturer for moving the puncture needle; pressure reducer for putting the punctured portion of the specimen sampling portion punctured by the puncture needle, together with a containing space for the puncture needle, into a reduced-pressure condition; measurer for measuring the amount of a predetermined component in the blood sampled from the punctured portion; and a chip retracting mechanism for moving the chip in a direction away from the specimen sampling portion while maintaining the reduced-pressure condition generated by the pressure reducer.

Claims

1. A component measuring instrument used by mounting therein a chip comprising a puncture needle and a contact portion for making contact with a specimen sampling portion, comprising:

a specimen sampling portion application portion which is capable of having a specimen sampling portion to be punctured applied thereon;

puncturing means for moving said puncture needle to puncture the specimen sampling portion applied onto said specimen sampling portion application portion;

pressure reducing means for putting the punctured portion of the specimen sampling portion punctured by said puncture needle, together with a containing space for said puncture needle, into a reduced-pressure condition;

measuring means for measuring the amount of a predetermined component in a blood sample from the punctured portion; and

a chip retracting mechanism for moving said chip, including said puncture needle and said contact portion, in a direction away from the specimen sampling portion, said contact portion being kept in contact with a surface of the specimen sampling portion as said chip moves in said direction so as to maintain said reduced-pressure condition generated by said pressure reducing means.

2. The component measuring instrument as set forth in claim 1, wherein the movement of said chip is carried out on the basis of said puncturing means in the condition where said chip is attached to said puncturing means.

3. The component measuring instrument as set forth in claim 1, wherein said chip retracting mechanism is operated by utilizing a pressure reducing force generated by the operation of said pressure reducing means.

4. The component measuring instrument as set forth in claim 3, wherein

said chip retracting mechanism comprises a pressure reduction chamber, and at least one passage having a high air passage resistance for communication between said pressure reduction chamber and said containing space, and

the pressure inside said pressure reduction chamber is reduced through said passage, thereby moving said chip in a direction away from the specimen sampling portion application portion.

5. The component measuring instrument as set forth in claim 1, wherein said chip retracting mechanism has a drive source for electric driving, and said chip retracting mechanism is operated by the driving of said drive source.

6. The component measuring instrument as set forth in claim 5, wherein said drive source is a solenoid.

7. The component measuring instrument as set forth in claim 1, wherein said chip retracting mechanism has biasing means such that said chip is returned to a previous position by said biasing means when the operation of said chip retracting mechanism is canceled.

8. The component measuring instrument as set forth in claim 1, wherein

said component measuring instrument comprises a housing for holding said chip and incorporating said puncturing means therein, and

said pressure reducing means puts said containing space in the housing into a reduced-pressure condition.

9. The component measuring instrument as set forth in claim 1, wherein the operation of said puncturing means and the operation of said pressure reducing means can be started substantially simultaneously.

10. The component measuring instrument as set forth in claim 1, wherein said chip retracting mechanism is operated in succession to the operation of said pressure reducing means.

11. The component measuring instrument as set forth in claim 1, comprising moving distance determining means for determining the distance of movement of said chip by said chip retracting mechanism.

12. The component measuring instrument as set forth in claim 1, wherein said contact portion includes an opening provided on the inside of said contact portion such that, when in use, said opening is capable of being closed by the specimen sampling portion.

13. The component measuring instrument as set forth in claim 12, wherein

said specimen sampling portion application portion has a specimen sampling portion application surface, and

the distal end of said contact portion is located at substantially the same horizontal plane as said specimen sampling portion application surface or slightly projecting from the horizontal plane of said specimen sampling portion application surface, in the condition where said chip is mounted in said component measuring instrument.

14. The component measuring instrument as set forth in claim 1, wherein said chip comprises a test paper, and a blood passage for supplying blood to said test paper.

15. The component measuring instrument as set forth in claim 14, wherein said test paper is a test paper for blood sugar measurement.

16. The component measuring instrument as set forth in claim 1, wherein said chip comprises:

a chip main body having a lumen portion; and

said contact portion defines an annularly projecting contact portion which is formed at the distal end of said chip main body and which is adapted to be brought into contact with the specimen sampling portion, wherein

at least a distal end portion of said contact portion decreases in thickness gradually along the direction from the proximal end toward the distal end thereof.